Northwestern University
Northwestern University
Evanston, IL 60208-3108
United States of Americahttp://www.nuance.northwestern.edu/biocryo/index.htmlcite this facility
Reiner Bleher
Last Updated: 04/25/2022
The integrated BioCryo Facility provides a comprehensive source for characterization of biological, soft matter, and hybrid samples with TEM (Transmission Electron Microscopy), SEM (Scanning Electron Microscopy), and STEM (Scanning Transmission Electron Microscopy) at cryogenic or at ambient temperature. We provide expertise and access to equipment for cryofixation and processing of frozen hydrated samples by high-pressure freezing and freeze substitution, plunge freezing, freeze fracturing/etching/coating, and cryo/ultramicrotomy. Conventional samples can be processed at ambient temperature with chemical fixation, dehydration, and resin embedment, or critical point drying. We also offer EDX (Energy Dispersive X-ray Spectroscopy) for elemental analysis.
In addition to offering training on instruments and sample preparation techniques, BioCryo staff mentors new users, advises on experimental design, and collaborates with researchers in experiments with challenging and unconventional samples. The BioCryo Facility participates in educational and outreach events, e.g. workshops, seminars, demos, and facility tours.
Services are offerred outside of Northwestern University
Consulting is offerred outside of Northwestern University