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Mary Beth Donnelley Clinical Pharmacology Core Facility

Northwestern University

303 E. Chicago Ave.

Ward Bldg, Room 13-208A

Chicago, IL 60611-3008

United States of America

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Primary Contact:

Michael Avram

Last Updated: 11/06/2018

Facility RRID


Facility Details

The mission of the Mary Beth Donnelley Clinical Pharmacology Core Facility is to provide state-of-the-art clinical pharmacologic support to Northwestern University investigators as an integral part of bench-to-bedside drug development.  The Clinical Pharmacology Core provides pharmacokinetic support for preclinical and clinical studies of cancer chemotherapeutic agents, analgesics, and other small molecules.  Expertise includes optimizing the design, conduct, analysis, interpretation, and reportage of pharmacokinetic studies.  Small molecule concentrations in plasma and other body fluids are measured using an Agilent HPLC system linked to an Applied Biosystems API 3000 triple quadrupole mass spectrometer.  Drug concentration histories are fitted to various compartmental pharmacokinetic models using commercially available and specialized software. For more information about this facility, click here.

Facility Policies

Services are offerred outside of Northwestern University