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Harvard Medical School
240 Longwood Ave.
Building C, room 303
Boston, MA 02115
United Stateshttps://cmi.hms.harvard.eduKelly Arnett
Last Updated: 03/09/2021
The Center for Macromolecular Interactions (CMI) in the department of Biological Chemistry and Molecular Pharmacology at Harvard Medical School provides scientific consultation, training and access to shared biophysical equipment for the characterization and analysis of macromolecules and their complexes.
The facility currently includes instruments measuring molecular interactions and assessing protein quality by Isothermal Titration Calorimetry (ITC), Surface Plasmon Resonance (SPR), Biolayer Interferometry (BLI), MicroScale Thermophoresis (MST), Differential Scanning Fluorimetry (DSF), Circular Dichroism (CD), Analytical Size Exclusion Chromatography with Multi-Angle Light Scattering (SEC-MALS), and Dynamic Light Scattering (DLS).
Services are offerred outside of Harvard Medical School
Consulting is offerred outside of Harvard Medical School
Differential Scanning Fluorimetry (DSF)
Isothermal Titration Calorimetry (ITC)
Biolayer Interferometry (BLI): ForteBio Octet RED384 and BLItz
Surface Plasmon Resonance (SPR): GE Biacore T200
Isothermal Titration Calorimetry (ITC): Microcal ITC200
MicroScale Thermophoresis (MST): NanoTemper Technologies Monolith NT.115pico
Circular Dichroism (CD): Jasco J815 Sprectropolarimeter
Differential Scanning Fluorimetry (DSF): Life Technologies Quant Studio 6
Differential Scanning Fluorimetry using intrinsic protein fluorescence (NanoDSF): NanoTemper Prometheus NT.Plex
Size-exclusion Chromatography with Multi-Angle Light Scattering (SEC-MALS): Wyatt Dawn Heleos and Optilab TrEx for MALS and DLS, with Agilent analytical SEC system
Dynamic Light Scattering (DLS): Wyatt Dynapro Plate Reader III
No publications have been associated with this facility
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https://coremarketplace.org/?FacilityID=997Keywords:
Scientific consultation, training, biophysical equipment, macromolecule characterization, analysis, protein quality, chromatography, USEDit
Resource Type:
Resource, service resource, core facility, access service resource
Citation:
Harvard Medical School Center for Macromolecular Interactions Core Facility (RRID:SCR_018270)
Facility Details
About This Facility
Services and Equipment
Publications
Associations
Metadata
