Facility Details

The BioMicro Center is an integrated genomics/bioinformatics facility located at MIT. The core has robust genomics technologies including Illumina HiSeq2000, NextSeq500 and MiSeq sequencing instruments as well as PacBio Sequel and Oxford Minion. The BioMicro Center has significant experience in preparing Illumina libraries for high-throughput sequencing samples using several different methods In addition, the BioMicro Center supports numerous additional technologies including an Agilent BioAnalyzer, AATI Fragment Analyzer, AATI FemtoPulse, three Roche LC480 qPCR machines, automated liquid handling through two Tecan Evo150s, TTP Labtech Mosquito HV. The center also supports 10X Chromium and single cell work using NamoCell single cell dispenser and custom oligo synthesis using a Dr.Oligo 192.

The BioMicro Center also supports robust informatics and bioIT tools. With six PhD level bioinformaticists on staff and three BioIT specialists, the Center has the experience and staff to handle the informatics and IT challenges. The core administers ~2PB of data storage on several platforms, including a 600TB Isilon server. The core also hosts a 400 processor Dell cluster and a Dell Quad Core 2950 application server for Illumina sequencing and bioinformatic applications. All application servers and storage servers are interconnected by 1gigabyte private networks or by fiber optic lines and are administered by IT staff that are part of the BioMicro Center. The servers are configurable to provide secure data storage for clinical data if required.

The BioMicro Center serves the Koch Instistute as the Genomics Core and the Bioinformatics and Computing Core and the MIT Center for Environmental Health Sciences as part of the Genomics and Imaging Core Facilities