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CryoEM & Advanced BioEM - Nanotechnology Materials Core @ MIT

500 Main Street

Room 76-037

Cambridge, MA 02139

United States

https://ki-sbc.mit.edu/nanotechnology-materials/pricing

Google Maps Location

cite this facility

Primary Contact:

Abigail Lytton-Jean

Last Updated: 02/12/2025

Facility RRID

RRID:SCR_018674

Additional Citation Identifiers

P30-CA140512P30CA014051-39

Facility Details

We provide services and instrumentation for imaging and characterization of bio- and nanomaterials with a strong focus on biological sample preparation. Some instruments are available for independent use. We also provide full service TEM, cryoTEM, SEM/FIB and cryoSEM/FIB, cryoFluorscence, sample preparation and imaging. Additionally, we conduct CLEM and cryoCLEM workflows utilizing cryoFluorescence, cryoSEM and cryoFIB with a focus on bio samples. In some cases the endpoint imaging is in the SEM/FIB (2D or 3D volumeEM). In other instances samples are transferred to one of a selection of cryoTEMs. We also provide immunoEM. In addition to imaging services we provide training on instruments for independent user access to: SEM, TEM, rheometer, AFM, DLS, and Spectradyne (counting & sizing nanoparticles). Our instruments and services are available to both non-profit and for-profit entities.

Funding Info

NIH - 09/26/2015 - Nanotechnolgy

is_active:

No

budget_end:

04/30/2016

date_added:

09/26/2015

agency_code:

NIH

fiscal_year:

2015

project_num:

2P30CA014051-44

award_amount:

$173,158.00

budget_start:

07/09/2015

org_name:

MASSACHUSETTS INSTITUTE OF TECHNOLOGY

org_state:

MA

org_country:

UNITED STATES

org_zipcode:

021421029

primary_duns:

001425594

abstract_text:

A major focus of the Koch Institute is the development of new materials systems and biomedical devices for biomarker detection, imaging modalities, and targeted therapies and vaccines. Center Members are employing a wide range of materials for these goals, including synthetic polymers and copolymers, synthetic and naturally derived peptides and proteins, polysaccharides, inorganic and organic nanoparticles, and colloidal systems. It is essential that Center Members can conduct high resolution and surface imaging, and chemical and physical analyses of these materials. In the current period, a Nanotechnology Materials Core was established with the support of CCSG Developmental Funds and non-renewable support from MIT. The Core is located in custom designed space within the new Koch Institute building, and has a wide range of state-of-the-art instrumentation for imaging, physical, chemical and mechanical analyses, and an expert staff. In the upcoming period, the Nanotechnology Materials Core will continue to offer a wide range of state-of-the-art characterization capabilities that are essential to the Koch Institute mission. Thus, CCSG funds are requested to support the continued operation of the Nanotechnology Materials Core as an established Shared Resource.

project_title:

Nanotechnolgy

contact_pi_name:

HAMMOND, PAULA T

total_cost:

$173,158.00

Facility Policies

Services are offerred outside of Massachusetts Institute of Technology

Consulting is offerred outside of Massachusetts Institute of Technology