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University of Pennsylvania Perelman School of Medicine Human Immunology Core Facility

University of Pennsylvania

United States of America

https://pathbio.med.upenn.edu/hic/site/

Primary Contact:

Eline Luning Prak

Last Updated: 06/15/2022

Facility RRID

RRID:SCR_022380

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Facility Details

The Human Immunology Core (HIC) provides wet bench expertise and infrastructure support for early phase clinical trials and other investigations. The HIC offers online ordering of purified cell subsets from HLA-typed healthy human apheresis donors. HIC staff are internally and externally qualified to perform blood (PBMC) and tissue processing for viable cryopreservation following validated standard operating procedures. The HIC also offers a wide range of immunological assays including digital ELISA, ELISA, ELISPOT, Luminex, flow cytometry and immune repertoire profiling (NGS of BCR and TCR rearrangements in bulk and single cell formats). The HIC offers investigators expertise and guidance in study design, sample processing, regulatory compliance, immunology assay design and validation, data analysis and presentation, and grant writing support.