University of Pennsylvania
United States of Americahttps://www.med.upenn.edu/cores/assets/user-content/documents/HTSC_overview_27May2015.pdfcite this facility
Sara Cherry
Last Updated: 06/15/2022
Core provides distribution of lentivirus based shRNA and cDNA plasmid DNA clones; technical expertise in developing biological assays (i.e. biochemical-, cell-, and high-content) in miniaturized, multiwell microtiter plates that are laboratory automation compatible; high-throughput chemical and functional genomic screening, including data analysis and interpretation. Our goal is to use cutting biological models to discover genes and small molecules that enable scientists to further study functions of poorly understood proteins, signaling pathways, and cells in complex biological process relevant to human physiology and disease.