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All Facilities >> Rockefeller University >> Fisher Drug Discovery Resource Center (High Throughput Screening)
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Fraser Glickman
Last Updated: 12/23/2022
The Fisher Drug Discovery Resource Center (DDRC) guides researchers in drug discovery by improving the efficiency of their bioassays, identifying compounds and molecular targets, and in utilizing technologies for the measurement of drug/receptor interactions. The center has a collection of 420,000 compounds, along with semi-automated liquid pipetting devices, computational techniques and supports a broad diversity of bio-assay techniques, typically found in drug discovery programs. The center also has spectroscopic and biophysical instruments for use in studies of the interactions of drugs with their targets.
Services are offerred outside of Rockefeller University
Consulting is offerred outside of Rockefeller University
Biotek EL406 Microtiter Plate Washer
Microplate washer that is equipped for full plate washing along with three reagent dispensers in one and includes washing and dispensing for standard assays, biomagnetic separation and vacuum filtration protocols. [Product Link]
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BioTek MultiFlo FX Multi-Mode Dispenser
Automated multi-mode reagent dispenser for 6- to 1536-well microplates. [Product Link]
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BioTek Synergy Neo2 Hybrid Multi-Mode Microplate Reader
Microplate reader that is designed for a screening laboratory and combines variable bandwidth quad monochromators, sensitive high transmission filter-based optics, laser TRF and up to 4 PMTs to provide fast measurements. [Product Link]
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Molecular Devices ImageXpress High Content Confocal Imaging System
ImageXpress Micro Confocal system is a high-content solution that can switch between widefield and confocal imaging of fixed and live cells. It can capture high quality images of whole organisms, thick tissues, 2D and 3D models, and cellular or intracellular events. The spinning disc confocal and sCMOS camera enable imaging of fast and rare events like cardiac cell beating and stem cell differentiation. With MetaXpress software and flexible options like water immersion objectives to choose from, the system enables many confocal imaging applications from 3D assay development to screening. [Product Link]
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Wyatt DynaPro III Plate Reader
Plate Reader for dynamic light scattering (DLS) and static light scattering (SLS) measurements of the size, molecular weight and interactions of proteins, nanoparticles and other macromolecules in situ in industry-standard microwell plates. No liquid handling occurs after dispensing into the plates, to maximize throughput and minimize sample carryover. [Product Link]
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https://coremarketplace.org/?FacilityID=431Institution
Institution ROR ID: https://ror.org/0420db125Keywords:
USEDit, ABRF, HTSRC, DDRC, drug discovery, bioassays, identifying compounds and targets, drug receptor interaction measurement technology
Resource Type:
service resource, core facility, access service resource
Citation:
Rockefeller University Fisher Drug Discovery Core Facility (RRID:SCR_020985)
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Facility Details
About This Facility
Services and Equipment
Publications
Awards & Associations
Metadata
Other Facilities at this Institution:
