The CoreMarketplace: UW Transgenic Resources Program (TRP)

1705 NE Pacific St

Dept of Comparative Medicine, HSB I-458

Seattle, WA 98195

United States

http://www.uwtransgenics.org/

Google Maps Location

cite this facility

Primary Contact:

Robert J Hunter

Last Updated: 09/25/2024

Facility RRID

RRID:SCR_017863

Facility Details

The Transgenic Resources Program (TRP) is a core facility that creates transgenic and gene-targeted mice using pronuclear microinjection, targeted ES cell microinjection, and CRISPR-Cas9 gene editing. The TRP also offers mouse rederivation services to create specific pathogen free mice or to revive cryopreserved mouse lines. Additionally, embryo and sperm cryopreservation services are available to provide long-term storage of valuable mouse strains or stocks. Our facility is available to all University of Washington investigators and outside institutions.

Facility Policies

Services are offerred outside of University of Washington

Consulting is offerred outside of University of Washington

Services offered:

Cell Culture

CRISPR

CRISPR Injection Services

CRISPR/Cas Project Design

Embryo Cryopreservation & Recovery Services

ES Cell Electroporation

ES Cell Injection

ES Cell Technology (Mouse)

Transgenics

Facility Equipment

No additional equipment has been listed

Publications

Publications associated with this facility (Click To View):

1.) Guo R, Hua Y, Ren J, Bornfeldt KE, Nair S (2018 Jun 7). Cardiomyocyte-specific disruption of Cathepsin K protects against doxorubicin-induced cardiotoxicity. Cell death & disease, 9(6), 692. doi: 10.1038/s41419-018-0727-2. PMID: 29880809.

2.) Yamamoto K, Miki Y, Sato M, Taketomi Y, Nishito Y, Taya C, Muramatsu K, Ikeda K, Nakanishi H, Taguchi R, Kambe N, Kabashima K, Lambeau G, Gelb MH, Murakami M (2015 Oct 19). The role of group IIF-secreted phospholipase A2 in epidermal homeostasis and hyperplasia. The Journal of experimental medicine, 212(11), 1901-19. . PMID: 26438362.

3.) Chen J, Kaiyala KJ, Lam J, Agrawal N, Nguyen L, Ogimoto K, Spencer D, Morton GJ, Schwartz MW, Dichek HL (2015 Apr). In vivo structure-function studies of human hepatic lipase: the catalytic function rescues the lean phenotype of HL-deficient (hl-/-) mice. Physiological reports, 3(4), . . PMID: 25862097.

4.) Jhingran A, Kasahara S, Shepardson KM, Junecko BA, Heung LJ, Kumasaka DK, Knoblaugh SE, Lin X, Kazmierczak BI, Reinhart TA, Cramer RA, Hohl TM (2015 Jan). Compartment-specific and sequential role of MyD88 and CARD9 in chemokine induction and innate defense during respiratory fungal infection. PLoS pathogens, 11(1), e1004589. doi: 10.1371/journal.ppat.1004589. PMID: 25621893.

5.) Miki Y, Yamamoto K, Taketomi Y, Sato H, Shimo K, Kobayashi T, Ishikawa Y, Ishii T, Nakanishi H, Ikeda K, Taguchi R, Kabashima K, Arita M, Arai H, Lambeau G, Bollinger JM, Hara S, Gelb MH, Murakami M (2013 Jun 3). Lymphoid tissue phospholipase A2 group IID resolves contact hypersensitivity by driving antiinflammatory lipid mediators. The Journal of experimental medicine, 210(6), 1217-34. . PMID: 23690440.

Associations

Metadata

Links

All the links listed resolve to this core profile

https://coremarketplace.org/?FacilityID=675
https://coremarketplace.org/RRID:SCR_017863

Institution

Institution ROR ID: https://ror.org/00cvxb145

SciCrunch Data Imports (data maintained by https://scicrunch.org)

Keywords:

Transgenic, gene, targeted, mice, pronuclear, microinjection, ES cell, CRSPR, Cas9, editing, pathogen, free, cryopreserved, line, embryo, sperm, electroporation, fertilization, service, core, ABRF

Resource Type:

access service resource, service resource, core facility

Citation:

University of Washington Transgenic Resources Program Core Facility (RRID:SCR_017863)

UW Transgenic Resources Program (TRP) (Transgenics)

Primary Contact:

Facility RRID

Facility Details

Facility Policies

(To see more facility information, click the in the upper right)

Services offered:

Facility Equipment

(To see more facility information, click the in the upper right)

Publications

(To see more facility information, click the in the upper right)

Associations

(To see more facility information, click the in the upper right)

Metadata

SciCrunch Data Imports (data maintained by https://scicrunch.org)

Facility Profile QR Code (links to this profile)

(To see more facility information, click the in the upper right)

Contact Robert J Hunter

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UW Transgenic Resources Program (TRP)

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