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Protein Production & Analysis

Sanford-Burnham Medical Research Institute

10901 N. Torrey Pines Rd.

La Jolla, CA 92037

United States of America

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Primary Contact:

Andrey Bobkov, Ph.D.

Last Updated: 08/20/2012

Facility Details

Variety of protein production services including cloning, expression optimization, development of protein purification protocols, and protein preparation. E. coli, insect (SF9, baculovirus) and mammalian (293) systems are available for protein expression. Our analytical services are focused on biophysical characterization of structural and functional properties of proteins in solution, under native, non-denaturing conditions. We can perform quality control of protein samples (folding, stability, aggregation, etc.); characterize protein conformation and shape in solution; and measure protein binding to proteins, peptides, small molecules and other ligands (including determination of equilibrium (Kd) and kinetic rate (kon, koff) constants, stoichiometry, binding enthalpy and entropy).

Facility Policies

Services are offerred outside of Sanford-Burnham Medical Research Institute

Consulting is offerred outside of Sanford-Burnham Medical Research Institute