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All Facilities >> Dartmouth Cancer Center >> DCC - Microscopy Shared Resource (Microscopy (Electron, Fluorescence, Optical))
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One Medical Center Drive
Dartmouth Cancer Center, Borwell 338 West
Lebanon, NH 03756
United Stateshttps://cancer.dartmouth.edu/scientists-researchers/microscopy-resourcecite this facility
Radu V Stan
Last Updated: 05/22/2025
Light microscopy imaging facility within the Dartmouth Cancer Center. Services offered: confocal microscopy with Airyscan, multispectral imaging slide scanner, high thoughput brightfield and multichannel fluorescence microscopy of live cells, multichannel TIRF microscopy, photopatterning and microfabrication.
Services are offerred outside of Dartmouth Cancer Center
Consulting is offerred outside of Dartmouth Cancer Center
BioTek Cytation 5 Cell Imaging Multi-Mode Reader
Multi-mode plate reader that offers up to 60x magnification in fluorescence, brightfield, high contrast brightfield, color brightfield and phase contrast for maximum applications reach. The multi-mode detection modules include filter- and monochromator-based fluorescence detection, luminescence and UV-Vis absorbance detection. [Product Link]
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Olympus IX73 Inverted Microscope
Olympus IX73 inverted microscope has been integrated into our IXplore systems. IXplore Systems are designed to provide solutions-based packages that suit your research application needs. [Product Link]
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Olympus IX83 Automated Fluorescence Microscope
The Olympus IX83 inverted microscope has been integrated into our IXplore systems. IXplore Systems are designed to provide solutions-based packages that suit your research application needs. [Product Link]
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Zeiss LSM 800 with Airyscan Confocal Laser Scanning Microscope
Confocal Laser Scanning Microscope with Airyscan detector
No additional equipment has been listed
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https://coremarketplace.org/?FacilityID=1729Institution
Institution ROR ID: https://ror.org/044b05b34Keywords:
USEDit, ABRF, light microscopy imaging, confocal microscopy, photopatterning, microfabrication, fluorescence microscopy, multispectral imaging slide scanner,
Resource Type:
service resource, access service resource, core facility
Citation:
Dartmouth College Microscopy Shared Resource Core Facility (RRID:SCR_023478)
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Mass Spectrometry
Spectroscopy
Brian Jackson
HB 6105 Fairchild Building
Hanover, NH 03755 - United States of America
http://www.dartmouth.edu/~toxmetal/resources/cores/analysis/index.html
RRID:SCR_009777
Analysis of elemental composition of biological tissues and fluids by Inductively Coupled Plasma Mass spectrometry. Analysis of Arsenic species in urine and blood by chromatography-ICP-MS. Laser ablation analysis of tissue sections for imaging of elemental distributions.
This facility provides services outside its institution
This facility provides consulting outside its institution
05/22/2025
Cryo-Electron Microscopy
Electron Microscopy
Microscopy
Outreach
Spectroscopy
Maxime Guinel
Dartmouth College
7605 Remsen
Hanover, NH 03755 - United States of America
RRID:SCR_017754
Dartmouth Electron Microscope Facility facility provides access to scanning (conventional and FEG, ESEM, cryo and EDS, EBSD and direct-write E-beam lithography) and transmission (conventional and FEG and EDS) electron microscopes, scanned probe microscope (AFM), Raman confocal light microscope.
Outside users are welcome.
This facility provides services outside its institution
This facility provides consulting outside its institution
07/23/2018
Biorepository
Torrey Gallagher
One Medical Center Drive
Borwell 708 East
Lebanon, NH 03756 - United States
RRID:SCR_023735
The Dartmouth-Hitchcock Health Biorepository (DH-Biorep) is a unique institutional resource collaboratively run by the Office of Research Operations and the Department of Pathology and Laboratory Medicine that provides services in support of our Research Communities and in alignment with Institutional Review Board (IRB)-approved protocols including Clinical Trials, industry-sponsored, and internal scientific investigations.
This facility does not provide services outside its institution
This facility does not consult outside its institution
06/27/2023
10x Genomics
ATAC-Seq
DNA Analysis
DNA Isolation
Genomics
Genotyping
Metagenomics Analysis
Methylation Analysis
Microarray
Nanopore Sequencing
Nanostring
Nanostring NCounter
Ribosomal Reduction
RNA analysis
RNA Integrity
RNA Isolation
Sequencing - DNA Sequencing
Sequencing - Next Generation Sequencing (NGS)
Single-Cell Analysis
Single-cell Sequencing
Single-molecule Imaging
Spatial Transcriptomics
Whole Exome Sequencing
Whole Genome Sequencing
Genomics / Genome Analysis and Technologies
Fred Kolling
1 Medical Center Dr
Rubin 670
LEBANON, NH 03756 - United States
https://cancer.dartmouth.edu/scientists-researchers/molecular-biology-resource
RRID:SCR_021293
Other CIDs:P30CA023108
P30CA023108-41
Services and instrumentation that enable DNA/RNA extraction and quality control, next-generation sequencing, epigenetic profiling and microarray analysis on a whole-genome scale, from the level organisms to single cells. Sanger Sequencing and Gene Expression assays with the NanoString nCounter Max System. We care for a wide range of molecular biology related instruments available for use by individuals on a walk-up basis.
This facility provides services outside its institution
This facility provides consulting outside its institution
01/31/2025
Affinity Purification Mass Spectrometry (APMS)
Crosslinking Mass Spectrometry
Gel Band Identification
Intact Protein Mass Spectrometry
Interactomics
Label Free Quantitative Proteomics
Mass Spectrometry - Proteins And Peptides
Post Translational Modification Analysis
Proteomics
Quantitative Phosphoproteomics
Quantitative Proteomics - TMT
Targeted Peptide Quantification
Proteomics
Anna Schmoker
1 Medical Center Drive
Rubin 7
Lebanon, NH 02769
RRID:SCR_026076
We offer quantitative and qualitative proteomics services using LC-MS/MS technologies. Our rates include sample preparation from harvested cell pellets, elutions post-enrichment or purification, or gel bands through data acquisition, quantification, and statistical analysis.
This facility provides services outside its institution
This facility provides consulting outside its institution
11/21/2024
Bioinformatics
Owen Wilkins
1 Medical Center Drive
Willamson Translation Research Building
Lebanon, NH 03756 - United States of America
https://sites.dartmouth.edu/cqb/projects-and-cores/data-analytics-core/
RRID:SCR_025383
The Genomics Data Sciences Core (GDSC) at Dartmouth offers comprehensive services to support the bioinformatic, computational, and statistical analysis of genomics data. We maintain a suite of standardized analysis pipelines for common data types like RNA-seq, ATAC-seq, and genome assembly. For more complex datasets, such as single-cell genomics, we provide tailored analysis solutions. Our team assists with all project stages, from experimental design to publication support and data management. Additionally, the GDSC hosts several multi-day bioinformatics workshops designed to introduce fundamental concepts for analysis of genomics data.
This facility provides services outside its institution
This facility provides consulting outside its institution
05/28/2024
2D &
3D Illustration
3D &
4D Image Processing Stations
Acoustic Angiography
Analysis Workstations
Bioluminsecence Imaging
Brightfield Microscope With Axial Sectioning Capability
Brightfield Microscopy
Cell Imaging
Clinical Imaging - Small Animal (luminescence/fluorescence)
Clinical Imaging - Small Animal (X-ray, Ultrasound, microCAT, MRI)
Collaborative Cross Mice
Colony Management
Confocal Microscopy
Confocal/ Super Resolution Microscope
Crossing
Cryo Light Microscopy
Cryo-Electron Microscopy
Cryo-Electron Microscopy Of Vitrified Sections (CEMOVIS)
Cryo-Scanning Electron Microscopy
Differential Interference Contrast Microscopy
EDX
Electron Microscopy
Fabrication
Fluorescence Microscope With Optical Sectioning Capability
Focused Ion Beam (FIB)
Germfree Mice
High-plex Immunofluorescence
Image Aquisition
Image Processing And Analysis
Incucyte
Irradiation
Laser Scanning
Live Cell Imaging
MicroCT
MicroED
Microscopy
Microstructure Characterization
Microtomy/Electron
Molecular Imaging
Multiplex Fluorescence
Radu V Stan
1 Medical Center Drive
Lebanon, NH 03756 - United States
https://cancer.dartmouth.edu/scientists-researchers/irradiation-imaging-microscopy-animal-resource
RRID:SCR_025077
Other CIDs:5P30CA023108
The Irradiation, Imaging, Microscopy and Animal Cancer Models Shared Resource at Dartmouth Cancer center is an integrated resource offering services in Irradiation, pre-clinical imaging of small and large animals, light and electron microscopy as well as large and small animal cancer models.
The Irradiation Section assists investigators in radiation treatment planning and delivery of ionizing irradiation to cells, rodents and large animals with engineered, transplanted or spontaneous tumors.
The Imaging Section provides technologies for non-invasive, whole-animal imaging of animals used in preclinical research studies.
The Microscopy Section provides access to point scanning confocal microscopy with Airyscan super resolution, conventional bright field and fluorescence light microscopy, high throughput live imaging, automated slide scanning and image analysis resources. The electron microscopy resource provides state of the art scanning , transmission and scanning transmission electron microscopy.
The Animal Cancer Models section supports the generation and utilization of large and small animals for modeling cancer and other human diseases. The section has expertise in generating cancer models using wild type or genetically engineered animals in immunocompetent and immunocompromised backgrounds, as well as mice with a humanized immune system.
This facility provides services outside its institution
This facility provides consulting outside its institution
02/29/2024
Microscopy (Electron, Fluorescence, Optical)
Radu V Stan
1 Medical Center Drive
Borwell 318W
Lebanon, NH 03756 - United States of America
https://cancer.dartmouth.edu/scientists-researchers/microscopy-resource
RRID:SCR_025076
Other CIDs:5P30CA023108
The facility provides state of the art imaging instrumentation and analysis software along with training and expertise to ensure their proper and efficient use. Instrumentation and technologies available to users include: (i) Zeiss LSM800 AIRYSCAN confocal microscope, a point scanning confocal system with high sensitivity GaAsP detectors allows confocal imaging of live cells, fixed cells, and tissues. It has full stage environmental control (temperature, gas and humidity) and autofocus, allowing long time lapse experiments of live cells. The Airyscan 32-detector array allows super resolution imaging. The system is integrated by Zen software allowing 3-D reconstruction, co-localization, deconvolution and image tiling. (ii) PerkinElmer / Akoya Vectra 3.0 Automated Quantitative Pathology Imaging System is a brightfield and fluorescence whole slide scanner with multi-spectral acquisition and spectral unmixing capabilities, allows highly multiplexed biomarker imaging on tissues sections and cells. (iii) Agilent/BioTek Cytation 5 with BioSpa8 live-cell microscopy system for fluorescence and phase contrast microscopy suitable for high throughput and long-term studies of cell-cell interaction, cell proliferation, survival and migration. The system enables time-lapsed images and kinetic measurements from living cells over many days with up to eigth multi-well plates imaged independently. (iv) Olympus IX-83 ZDC2 microscope equipped with a PRIMO UV light-based bioengineering device for micropatterning and microfabrication. (v) Olympus IX73 Inverted Fluorescence Microscope: has a wide assortment of fluorescence filters and objectives allowing high quality image capture of slides/multi-well plates using immunohistochemistry (IHC) or fluorescence readily is achieved. Image analysis software hosted on appropriately powered workstations with cloud connectivity for high capacity storage provided by Dartmouth College: HALO3, Inform, Volocity, AutoDeblur, Image-J / Fiji.
The shared resource also provides state of the art instrumentation for transmission and scanning electron microscopy, housed in the Dartmouth Electron Microscopy Facility (director M. Guinel, PhD). Instrumentation avaiable: (vii) FEI Talos F200i (200kV TEM and STEM electron microscope (TEM), equipped for micro-analysis, and cryo-EM.
(viii) FEI Helios CX5 dual beam FIB-SEM system allowing high resolution electron and ion beam imaging, ion beam milling and automated imaging of biological samples for 3D reconstruction. The system is also equipped with three X-ray microanalysis detectors allowing elemental analysis of the specimens. The facility has instruments for specimen preparation for transmission and scanning electron microscopy including ultramicrotomes (Leica Ultracut UC6 and UC7), critical point dryer (Samdri-970), Leica ACE 600 coater and ThermoFisher Vitrobot..
This facility provides services outside its institution
This facility provides consulting outside its institution
02/27/2024
Computational - Bioinformatics
Computational - Biostatistics
Data Analysis
Data Analysis And Interpretation
Data Processing
Data Processing And Interpretation
Data Visualization
Metagenomics Analysis
Methylation Analysis
Power Analysis
Single-Cell Analysis
Owen Wilkins
Geisel School of Medicine at Dartmouth
1 Medical Center Dr
Lebanon, NH 03756 - United States
https://cancer.dartmouth.edu/scientists-researchers/biostatistics-bioinformatics-shared-resource
RRID:SCR_023683
We offer comprehensive statistical and bioinformatic analysis, consultation, collaboration, and technical services.
This facility provides services outside its institution
This facility provides consulting outside its institution
06/14/2023
Assay Development
Clinical Trial Support
Immunohistochemistry
Staining
Tissue Embed
Tissue MicroArray
Whole Slide Imaging
Amber Barrows
One Medical Center Drive
Lebanon, NH 03756 - United States
https://cancer.dartmouth.edu/scientists-researchers/pathology-shared-resource
RRID:SCR_023479
Dartmouth-Hitchcock Medical Center / Geisel School of Medicine
This facility provides services outside its institution
This facility does not consult outside its institution
04/18/2023
Assay Development
Assays and Measurements
Bioanalytical LC MS/MS
Bioshipping
Consultations
Pharmacokinetics
Plate Reader
Sample Preparation
Lionel D. Lewis
322 W Borwell Buildiing, Section of Clinical Pharmacology
Dartmouth Cancer Center, One Medical Center Drive
Lebanon, NH 03756 - United States
https://cancer.dartmouth.edu/scientists-researchers/clinical-pharmacology
RRID:SCR_000873
The Clinical Pharmacology (CP) Shared Resource has been in operation since 1993 and supports Dartmouth Cancer Center (DCC) investigators in the design, performance, data analysis, and interpretation of pharmacology objectives in preclinical (in vivo and ex vivo), clinical and epidemiological studies at the lowest cost and highest value possible.
This facility provides services outside its institution
This facility provides consulting outside its institution
04/01/2023
Assay Development
Assays and Measurements
Cell Culture
Cell Sorting
Clinical Research
Clinical Trial Support
Cytokine Assays
Data Analysis
FACS Cell Sorting
Flow Cytometric Analysis
Flow Cytometry Data Analysis
Immune Monitoring
Immunoassay
Luminex Bead Based Cytokine Assays
Luminex Services
Multi-color Flow Cytometry
Spectral Flow Cytometry
Tissue Culture
Flow Cytometry
Dan Mielcarz
710 Rubin Building
Lebanon, NH 03756 - United States of America
RRID:SCR_019165
We carry out customized end-point assays using human WB/PBMCs for clinical trials; ELISPOT, multiplex cytokine analysis, cell energy analysis, blood processing and cryopreservation.
We carry out up to 20-color flow cytometry phenotyping and up to 11-color FACS cell subset sorting. We are available for consultation, data analysis, and we offer a 5-lecture Flow Cytometry training course.
This facility provides services outside its institution
This facility provides consulting outside its institution
10/13/2022
Animal Husbandry
Cell Culture
Embryo Cryopreservation & Recovery Services
Genotyping
Necropsy
Rederivation (Mouse)
Surgical Services
Tissue Culture
Transgenics
Transgenics
Steve Fiering
1 Medical Center drive
DHMC
Lebanon, NH 03756 - United States of America
https://cancer.dartmouth.edu/scientists-researchers/mouse-modeling
RRID:SCR_021284
The mouse modeling supports the generation and utilization of genetically modified mice. We design and produce genetic constructs with the following methods: yeast and E.coli 'recombineering', ES cell targeting (transfection, drug selection, and expansion).
We produce transgenic mice: DNA injections into oocytes, ES cell injections into blastocysts. We also provide humanized immune system mouse models.
In addition we offer start to finish experiment services to assist your many needs, please ask for more info
There are many technician services (animal husbandry, IP and IV injections, blood drawing, necropsy and surgeries- embryo transfers, ovariectomy, vasectomy, tumor removal
This facility provides services outside its institution
This facility provides consulting outside its institution
06/01/2021
DNA Analysis
Genotyping
Microarray
Nucleic Acid Extraction
Matthew Ranson
1 Medical Center Drive
610W Borwell, HB 7556
Lebanon, NH 03756 - United States of America
RRID:SCR_017756
DartMouseâ„¢ is a not-for-profit core facility funded by the NIH. The mission of DartMouse is to facilitate the development of congenic mice in support of pre-clinical projects across the U.S. Use of DartMouse allows the generation of congenic mice in 5 generations (~1.5 year), vs. 10 generations (~3 years) required by conventional back-crossing. Investigators fill out our accession form and supply mouse tail clippings - from these DartMouse isolates genomic DNA and performs and analyzes complete genome-wide scans. We return data in graphical and spreadsheet formats, and make specific recommendations on breeder selection. In addition to helping investigators create congenic mice, we also provide a background check service to test the genetic purity of your mice. If there is contaminating genome present, we can then help you back-cross onto your inbred strain of interest. Chips use a 1449 SNP array covering the mouse genome with an average density of < 2 cM. Turnaround time from receipt of samples to results is less than 14 business days. Prices are competitive.
This facility provides services outside its institution
This facility provides consulting outside its institution
04/03/2017
BioBanking
Nucleic Acid Extraction
Protocol Development/Clinical Trial Coordination
Tom Palys
1 Medical Center Drive
HD 7927, Rubin 7
Lebanon, NH 03756 - United States of America
The Center for Molecular Epidemiology Biorepository Core of the Geisel School of Medicine at Dartmouth utilizes a combination of manual and advanced robotic liquid handing processes, as well as traditional and state-of-the art automated archival storage strategies (e.g. ambient temperature, 4°C, -20°C, -80°C, and liquid nitrogen) to provide standardized services to the to members of the research community. The Biorepository manages a broad range of adult, child and infant specimen types, such as blood and its components, urine, nails, meconium, stool, placenta, breastmilk, DNA and RNA, as well as various environmental samples. Specimen processing services include blood fractionation, lymphocyte isolation, aliquoting of specimens for archival storage, human and microbiome nucleic acid extraction, quantification and normalization, tissue separation and fixation, specimen retrieval, shipping and referral management services. The Biorepository Core also plays a critical role in the development of new projects by working with investigators to pilot and establish methods for collection, processing, archiving and subsequent referral of study specimens. The Biorepository has processed roughly over 21,000 adult and infant specimens and archived over 100,000 aliquots. The Biorepository also manages the Dartmouth Biospecimen Storage Facility, a secure, off-site facility dedicated to long term storage of specimens, providing 24 hour/7 day a week, real-time video surveillance, continuous and redundant monitoring of freezer temperatures and emergency response to users.
This facility provides services outside its institution
This facility provides consulting outside its institution
09/02/2016
Data Analysis
Heather Carlos
Norris Cotton Cancer Center
One Medical Center Drive
Lebanon, NH 03756 - United States of America
The primary mission of the GeoSpatial Resource is to support the implementation of geospatial analysis for cancer research. Our goal is to provide expert consultation and collaboration for research projects of in behavior, epidemiology, and health services research. The GeoSpatial Resource also strives to educate members of the community in different aspects of geospatial analysis by providing courses through TDI and at Dartmouth College. We can provide assistance with acquisition of spatial data, project design, spatial analysis and mapping.
This facility provides services outside its institution
This facility does not consult outside its institution
03/01/2012
Clinical Assessment (Hematology, Clinical Chemistries, etc.)
Mass Spectrometry
Lionel Lewis
1 Medical Center Drive
Lebanon, NH 03756 - United States of America
The Clinical Pharmacology Shared Resource operates in the Borwell Research Building at DHMC. In addition, to the biorepository function of our resource we also have bioanalytical hardware and computer hardware and state-of-the-art commercial software programs for application to individual and population-based pharmacokinetic and pharmacodynamic modeling, and modeling drug in vitro and in vivo combination drug effects.
This facility provides services outside its institution
This facility does not consult outside its institution
02/08/2012
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