Facility Details

The Irradiation, Imaging, Microscopy and Animal Cancer Models Shared Resource at Dartmouth Cancer center is an integrated resource offering services in Irradiation, pre-clinical imaging of small and large animals, light and electron microscopy as well as large and small animal cancer models.

The Irradiation Section assists investigators in radiation treatment planning and delivery of ionizing irradiation to cells, rodents and large animals with engineered, transplanted or spontaneous tumors.

The Imaging Section provides technologies for non-invasive, whole-animal imaging of animals used in preclinical research studies.

The Microscopy Section provides access to point scanning confocal microscopy with Airyscan super resolution, conventional bright field and fluorescence light microscopy, high throughput live imaging, automated slide scanning and image analysis resources. The electron microscopy resource provides state of the art scanning , transmission and scanning transmission electron microscopy.

The Animal Cancer Models section supports the generation and utilization of large and small animals for modeling cancer and other human diseases. The section has expertise in generating cancer models using wild type or genetically engineered animals in immunocompetent and immunocompromised backgrounds, as well as mice with a humanized immune system.