Geisel School of Medicine at Dartmouth
1 Medical Center Drive
610W Borwell, HB 7556
Lebanon, NH 03756http://www.dartmouse.org
Last Updated: 04/03/2017
is a not-for-profit core facility funded by the NIH. The mission of DartMouse is to facilitate the development of congenic mice in support of pre-clinical projects across the U.S. Use of DartMouse allows the generation of congenic mice in 5 generations (~1.5 year), vs. 10 generations (~3 years) required by conventional back-crossing. Investigators fill out our accession form and supply mouse tail clippings - from these DartMouse isolates genomic DNA and performs and analyzes complete genome-wide scans. We return data in graphical and spreadsheet formats, and make specific recommendations on breeder selection. In addition to helping investigators create congenic mice, we also provide a background check service to test the genetic purity of your mice. If there is contaminating genome present, we can then help you back-cross onto your inbred strain of interest. Chips use a 1449 SNP array covering the mouse genome with an average density of < 2 cM. Turnaround time from receipt of samples to results is less than 14 business days. Prices are competitive.
DNA extraction service is available for researchers at Dartmouth College and Dartmouth Medical School only.
Services are offerred outside of Geisel School of Medicine at Dartmouth
Consulting is offerred outside of Geisel School of Medicine at Dartmouth
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