The CoreMarketplace: UMMS Deep Sequencing Core

The Deep Sequencing Core provides a next-generation sequencing (NGS) platform for investigators using Massively Parallel Sequencing by Synthesis, or "Deep Sequencing". The core analyzes genomic DNA, DNA fractions (e.g. ChIP), cDNA, RNA, and many other library types, including 10X Chromium and NanoString, using an Illumina NovaSeq 6000 or MiSeq/MiSeq Dx. The Deep Sequencing Core provides assistance with sample preparation (also a service offering) and bioinformatics analysis. The Core offers sequencing on a Pacific Biosciences Sequel II as well through the PacBio Core Enterprise.

Facility Policies

Services are offerred outside of University of Massachusetts Medical School

Consulting is offerred outside of University of Massachusetts Medical School

(To see more facility information, click the in the upper right)

Services offered:

Assays and Measurements

ATAC-Seq

ChIP-Seq

Computational - Bioinformatics

Molecular Construct Services

Nucleic Acid Extraction

RNA analysis

RNAseq

Sequencing - DNA Sequencing

Sequencing - Next Generation Sequencing (NGS)

Single-cell Sequencing

Whole Exome Sequencing

Whole Genome Sequencing

Facility Equipment

Agilent 5300 Fragment Analyzer System

Fragment Analyzer System can separate up to 48 or 96 samples in parallel. [Product Link]

RRID:SCR_019411

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Illumina MiSeq System

Access focused applications such as targeted resequencing, metagenomics, small genome sequencing, targeted gene expression profiling, and more. MiSeq reagents enable up to 15 Gb of output with 25 million sequencing reads and 2 Ã— 300 bp read lengths. [Product Link]

RRID:SCR_020134

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Illumina MiSeqDx System

FDA regulated, CE IVD marked, NGS platform for in vitro diagnostic IVD testing. [Product Link]

RRID:SCR_020137

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Illumina NovaSeq 6000 Sequencing System

Unleashes groundbreaking innovations that leverage our technology Now you can get scalable throughput and flexibility for virtually any sequencing method, genome, and scale of project. [Product Link]

RRID:SCR_020150

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Pacific Biosciences Sequel II

Long-read sequencer

Pacific BioSciences Sequel II