Facility Details

The facility headed by Dr. Hong Cao has allowed UMMS scientists a unique opportunity to apply the tools and principles of chemistry to understand the processes of living cells.

The screening facility assists researchers in developing high-throughput (HT) screening assays, performs HT screens of chemical libraries to identify new small molecules that can be used to probe biological processes of interest.

The facility coordinates the screening efforts of UMMS researchers, providing access to diverse chemical libraries and state-of-the art instruments including robotic compound transfer, liquid-handling equipment, imagers and plate readers.

The information from all screens performed at the facility is collected and stored in a central database.

The Cheminformatics database allows researchers to rapidly evaluate and compare results of their screens and can also be used in the future to classify the function of lead structures and biological targets.