The CoreMarketplace: Penn State COM Biomolecular NMR

Our mission is to facilitate investigators to use multiple modern NMR applications, including structure elucidation of small molecules, triple resonance experiments of biomolecules, fragment-based drug discovery, metabolomic and tissue analyses.

Facility Policies

Services are offerred outside of Penn State College of Medicine

Consulting is offerred outside of Penn State College of Medicine

(To see more facility information, click the in the upper right)

Services offered:

Consultation

Data Analysis

Data Analysis And Interpretation

Data Processing

Data Processing And Interpretation

Metabolomics

NMR Medicinal Chemistry Support

NMR Quality Control For Biologic Drugs

Nuclear Magnetic Resonance (NMR)

Structural Biology

Structure Determination

Facility Equipment

Bruker 500 MHz NMR

Bruker 600 MHz NMR

No additional equipment has been listed

(To see more facility information, click the in the upper right)

Publications

Publications associated with this facility (Click To View):

1.) Ye Y, Liang X, Wang G, Bewley MC, Hamamoto K, Liu X, Flanagan JM, Wang HG, Takahashi Y, Tian F (2024 Mar 15). Identification of membrane curvature sensing motifs essential for VPS37A phagophore recruitment and autophagosome closure Communications Biology, 7(), 334. . PMCID: 10942982.

2.) Ye Y, Bewley MC, Wang HG, Tian F, Flanagan JM (2024 Mar). What's in an E3: role of highly curved membranes in facilitating LC3-phosphatidylethanolamine conjugation during autophagy. Autophagy, 20(3), 709-711. . PMID: 38032155.

3.) Ye Y, Tyndall ER, Bui V, Tang Z, Shen Y, Jiang X, Flanagan JM, Wang HG, Tian F (2021 Jan 14). An N-terminal conserved region in human Atg3 couples membrane curvature sensitivity to conjugase activity during autophagy. Nature communications, 12(1), 374. . ID: 33446636.

4.) Fu R, Gill RL Jr, Kim EY, Briley NE, Tyndall ER, Xu J, Li C, Ramamurthi KS, Flanagan JM, Tian F (2015 Nov 11). Spherical nanoparticle supported lipid bilayers for the structural study of membrane geometry-sensitive molecules. Journal of the American Chemical Society, 137(44), 14031-14034. . ID: 26488086.

5.) Tash BR, Bewley MC, Russo M, Keil JM, Griffin KA, Sundstrom JM, Antonetti DA, Tian F, Flanagan JM (2012 Jul 3). The occludin and ZO-1 complex, defined by small angle X-ray scattering and NMR, has implications for modulating tight junction permeability. Proceedings of the National Academy of Sciences of the United States of America, 109(27), 10855-60. . ID: 22711802.

6.) Wang X, Tash B, Flanagan JM, Tian F (2011 Feb). RDC derived protein backbone resonance assignment using fragment assembly. Journal of biomolecular NMR, 49(2), 85-98. . ID: 21191805.

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Associations

ABRF

Association of Biomolecular Resource Facilities

(To see more facility information, click the in the upper right)

Metadata

Links

All the links listed resolve to this core profile

https://coremarketplace.org/?FacilityID=1469
https://coremarketplace.org/RRID:SCR_023244

SciCrunch Data Imports (data maintained by https://scicrunch.org)

Keywords:

USEDit, ABRF, NMR applications, small molecules, triple resonance experiments, drug discovery, metabolomic and tissue analyses,

Resource Type:

core facility, access service resource, service resource

Citation:

Penn State College of Medicine Biomolecular NMR Core Facility (RRID:SCR_023244)

Penn State COM Biomolecular NMR (Nuclear Magnetic Resonance)

Primary Contact:

Facility RRID

Facility Details

Facility Policies

(To see more facility information, click the in the upper right)

Services offered:

Facility Equipment

(To see more facility information, click the in the upper right)

Publications

(To see more facility information, click the in the upper right)

Associations

ABRF

(To see more facility information, click the in the upper right)

Metadata

SciCrunch Data Imports (data maintained by https://scicrunch.org)

Facility Profile QR Code (links to this profile)

(To see more facility information, click the in the upper right)

Contact Fang Tian

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Penn State COM Biomolecular NMR

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