The CoreMarketplace: UA CBC Molecular Structures Core (MSC)

University of Arizona

1306 E. University Blvd

Tucson, AZ 85719

United States of America

https://cbc.arizona.edu/rss/molecular-structures-core

cite this facility

Quicklinks:

https://coremarketplace.org/UACBCMSC https://coremarketplace.org/RRID:SCR_022888

Facility LIMS Page

https://ua.ilab.agilent.com/service_center/show_external/4415?name=cbc-molecular-structures-core

Primary Contact:

Vlad Kumirov

Last Updated: 11/09/2022

Facility RRID

RRID:SCR_022888

Facility Details

The Molecular Structures Core (MSC) enables researchers to determine the structures and dynamics, or motions, of large biomolecules such as proteins and DNA to understand how they interact with each other and with small molecules such as drugs.

Facility Policies

Services are offerred outside of University of Arizona

Consulting is not offerred outside of University of Arizona

Services offered:

Nuclear Magnetic Resonance (NMR)

Protein NMR

Facility Equipment

No additional equipment has been listed

Publications

Publications associated with this facility (Click To View):

1.) François-Moutal L, Scott DD, Ambrose AJ, Zerio CJ, Rodriguez-Sanchez M, Dissanayake K, May DG, Carlson JM, Barbieri E, Moutal A, Roux KJ, Shorter J, Khanna R, Barmada SJ, McGurk L, Khanna M (2022 May 17). Heat shock protein Grp78/BiP/HspA5 binds directly to TDP-43 and mitigates toxicity associated with disease pathology. Scientific reports, 12(1), 8140. doi: 10.1038/s41598-022-12191-8. ID: 35581326.

2.) Francois-Moutal L, Scott DD, Khanna M (2021 Aug 5). Direct targeting of TDP-43, from small molecules to biologics: the therapeutic landscape. RSC chemical biology, 2(4), 1158-1166. doi: 10.1039/d1cb00110h. ID: 34458829.

3.) Schoenle MV, Li Y, Yuan M, Clarkson MW, Wilson IA, Peti W, Page R (2021 Jun 2). NMR Based SARS-CoV-2 Antibody Screening. Journal of the American Chemical Society, 143(21), 7930-7934. doi: 10.1021/jacs.1c03945. ID: 34018723.

4.) Torgeson KR, Clarkson MW, Kumar GS, Page R, Peti W (2020 Oct 2). Cooperative dynamics across distinct structural elements regulate PTP1B activity. The Journal of biological chemistry, 295(40), 13829-13837. . ID: 32737198.

5.) Lixa C, Clarkson MW, Iqbal A, Moon TM, Almeida FCL, Peti W, Pinheiro AS (2019 Oct 15). Retinoic Acid Binding Leads to CRABP2 Rigidification and Dimerization. Biochemistry, 58(41), 4183-4194. doi: 10.1021/acs.biochem.9b00672. ID: 31566355.

Associations

Metadata

Links

All the links listed resolve to this core listing

https://coremarketplace.org/?FacilityID=1585
https://coremarketplace.org/RRID:SCR_022888

SciCrunch Data Imports (data maintained by https://scicrunch.org)

Keywords:

USEDit, ABRF, determine structures and dynamics, determine motions, large biomolecules, small molecules interaction

Resource Type:

access service resource, service resource, core facility

Citation:

University of Arizona Molecular Structures Core Facility (RRID:SCR_022888)

UA CBC Molecular Structures Core (MSC) (Molecular Structure and Modeling)

Quicklinks:

Facility LIMS Page

Primary Contact:

Facility RRID

Facility Details

Facility Policies

(To see more facility information, click the in the upper right)

Services offered:

Facility Equipment

(To see more facility information, click the in the upper right)

Publications

(To see more facility information, click the in the upper right)

Associations

(To see more facility information, click the in the upper right)

Metadata

SciCrunch Data Imports (data maintained by https://scicrunch.org)

(To see more facility information, click the in the upper right)

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Contact Vlad Kumirov

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UA CBC Molecular Structures Core (MSC)

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