Core provides services to uncover the molecular functions and interactions of proteins, mass spectrometry instrumentation, expertise and guidance from experimental design to data interpretation.

The SSFF provides the following services on a recharge basis to the research community:
o Cell sorting and analysis of BSL-1 and BSL-2 samples, either with or without operator support.
o In-depth training for researchers who want to operate the instruments themselves.
o Consulting with researchers on design and data analysis of flow cytometry experiments.
o Maintaining a site license for FlowJo software (originally developed in the SSFF) for the University at large, providing a 65% savings to the Stanford community.
o Data management services, including on and off-site backups, of all data generated in the Facility for the past 10 years.
In addition the SSFF stays abreast of, and tests, new applications and reagents, and makes the results available to its user base, either through postings or a series of sponsored lectures and seminars.

The Stanford University MicroCT Facility (MCT) is a shared user facility that supports scientific research across various fields such as the earth, materials and biological sciences.

The MCT provides its users with a non-destructive technique to visualize and measure the internal 3D structures and properties of a broad variety of opaque materials

High-performance computing facility. Its resources have been designed to support labs engaged in genetics and bioinformatics research, but are open to anyone on campus. SCG Cluster is optimized to support large memory, single-node threaded applications as well as applications and workflows that require many small files.

Provides services with computing and data information for research proposals, data storage platforms,consultation,computational platforms and resources.Some services relate directly to physical hardware, including hosting and system administration. Hosting largely takes place at Stanford Research Computing Facility data center designed specifically to host high density, power consumptive computing equipment. SRCF is intended to meet research server hosting needs of campus for years to come.

Ecosystems Laboratory provides bench space, laboratory supplies, chemicals, sample preparation equipment, and sample storage space to enhance and facilitate research within Stanford University community.

Core offers qualitative and quantitative characterization of Earth materials by providing optical microscopes for high-resolution imaging of loose materials and thin sections, computational resources for image processing, and bench space for light processing of samples before or after use of the Sample Preparation Lab.

Provides Stanford researchers with expertise, resources, technology, and training to conduct large library screens of small molecules, siRNA, and cDNA. Joint effort between Sarafan ChEM-H and the Department of Chemical and Systems Biology, to provide support and services that are often inaccessible to academic labs.

Advanced 3D printing facility enables digital design, prototyping, and small scale production as integrated innovation hub and shared use facility for innovation and commercialization for investigators spanning the Stanford campus and Silicon Valley.

Provides access to ultrasound, MRI, CT, and PET, instruments developed specifically for small animal work and photoacoustic imaging. All instruments are designed to image living subjects and allow for repeated imaging. The flexibility and rapid analyses of such animal models greatly accelerate the development of molecular imaging strategies.Facility houses surgical procedure room, histology slide scanner that converts glass slides into digital slides using both brightfield and fluorescence, and advanced image analysis workstations.Instruments include MicroPET Imaging Systems,Optical Imaging Systems,UltraSound Imaging System,Photoacoustic Imaging System,X-Ray Computed Tomography Imaging System,Magnetic Resonance Imaging.

Core for understanding Earth surface processes in bedrock, soil, water, and sediment. Interactions between cosmic rays and Earth’s upper atmosphere create unique isotopes both in the atmosphere and in materials on Earth’s surface. By assessing the ratios and/or concentrations of these isotopes, we can get a deeper insight into the exposure age, soil production rate, catchment-averaged erosion, and processes of Earth’s varied landscapes.

Shared analytical facility specialized in areas of radiogenic isotope geochemistry, non-traditional stable isotope geochemistry, and low blank concentration determinations of natural and engineered materials. Provided equipment includes triple-quad ICP-MS (Agilent 8900) with laser ablation intake system (AS RESOlution laser system), multi-collector ICP-MS (Neptune Plus), and specially designed Picotrace metal-free low particulate clean laboratory. Produces high quality isotopic and trace element data. Offers training.

The shared Geomicrobiology analytical facilities consist of four different labs in the Green Earth Sciences Building. Main areas of study are: 1) molecular, bio(geo)chemical, and ecological aspects of the microbial cycling of nitrogen, carbon, and metals in the environment; 2) diversity, distribution, and activity of microorganisms driving greenhouse gas cycling in the ocean and beyond; 3) molecular biomarkers in modern organisms to refine our interpretations of the microbial fossil record.

Core for collaborative human neuroscience research provides access to technology and expertise to high density electroencephalography recording and transcranial magnetic stimulation studies in human subjects.

Core in part of Bioengineering Department at Stanford University and is the main service provider of integrated microfluidic devices on Stanford campus servicing universities and academic institutions.

Provides services for all departments on campus, including library of materials and parts suppliers, arranging for off-campus services such as plating and specialized machining services,help with laboratory and research apparatus and repair of existing equipment, designs from sketches to final assembly by mechanical means (welding, brazing or soldering),computer numerically controlled mill and lathe, electro discharge machining.

Academic cost recovery center, operates number of HPC clusters to enable larger simulations, deeper analyses, and faster computation times than are possible using computers available to individual researchers. Provides mass data storage and archival systems to store data.

Provides creation of biomaterials and drug delivery agents, expertise toward designing and analyzing biomaterials, development of drug delivery devices and formulations, pharmacokinetic and pharmacodynamic studies, and development of materials for biomedical applications.

Houses optical spectroscopy instruments including Fluorolog 3 Fluorimeter,Vertex 70 FTIR with RAM II Raman accessory, Cary 6000i UV/Vis/NIR Spectrometer.

Core for assisting with custom instrumentation and equipment needs at affordable price.Projects devices include microcontrollers, LCD displays, keypad interfaces, serial communication, signal conditioning electronics, analog and digital computer interfaces, photomultiplier tube amplifiers, DC motor, stepper motor and linear motor controllers, servomotors, rotary encoders, timed sequenced equipment, temperature controllers, peltier devices, solenoid valves, actuators, force transducers, profusion chambers, microscope adapters as well as mechanical design and limited machine shop services.

Offers clinical laboratory services including hematology, cytology, serum chemistry, electrolyte analysis, coagulation profiles, fluid analysis, serology/immunology, parasitology, and microbiology; Specializes in diagnostic and research needs of laboratory animals. Committed to improving diagnostics, developing additional reference ranges for various clinical pathology parameters in laboratory animals, and supporting health surveillance and disease management.

Core houses 5 Varian NMR Spectrometers including Inova 300, Varian 400, Neo 400, Inova 600, Inova 500.

Provides guidance, access, and hands-on training for rock preparation, equipment uses, and mineral separation techniques. The most common uses are Powdering samples for geochemical or isotopic analysis;Cutting/drilling/coring rocks for geophysical analysis or generating thin section billets;Separation of zircon and apatite from quartz and feldspar;Soil and/or sediment sieving.

Provides instruments for solid, aquouse and gas sample analyses, quantitative analysis, technical expertise to members of Stanford community.

Facility is equipped with JEOL JXA-8230 SuperProbe electron microprobe. Electron microprobe measures elemental compositions of solid samples by detecting the X-rays emitted on excitation by focused electron beam, down to spatial resolution of about 1 micron. All elements heavier than beryllium can be detected, at concentrations as low as 10s of ppm. Highly quantitative analyses are made using 5 wavelength dispersive X-ray spectrometers (WDS) with calibrations based on known standard materials. Compositional images (maps) can readily be obtained with backscattered electrons (sensitive primarily to mean atomic number), or with WDS or EDS X-ray data. The instrument is adjacent to the Stanford Nanocharacterization Laboratory (SNL), at the west end of the first floor of the McCullough Building.

Stable Isotope Biogeochemistry Laboratory at Stanford University's School of Earth Sciences provides analytical facilities and technical expertise to members of Stanford community who need to determine stable isotope ratios of variety of organic and inorganic materials from both terrestrial and marine environments.

Core for comprehensive examination of evolution of Earth's crust using geochronologic approaches. Provides spectrum of analytical facilities that are all housed within School of Earth, Energy and Environmental Sciences.Provides data to many disciplines throughout geosciences, including tectonics, geodynamics, petrology, geochemistry, geomorphology, sedimentology, stratigraphy, paleontology, and paleoclimatology.

Used to explore new visualization technologies related to study of brain.Provides equipment and expertiese to help with project setup and planning. Hosts adaptive optics system that uses optical principles originally developed for visualizing distant stars to enable high resolution imaging of retina in human subjects.

Provides preclinical Magnetic Resonance Imaging technology and expertise to Stanford community. Offers range of support from full project to independent user operation and training.

Core centralizes process of producing and distributing viral vectors and cDNA plasmids.

Laboratory at Wu Tsai Neursciences Institute provides preclinical discovery platform for central nervous system target validation in preclinical in vivo and in vitro models. Neurobehavioral assessment tools in CNS disease models provide platform for screening and profiling of experimental therapeutics and genetic rodent models. Used to support understanding of human CNS disorders and development of therapeutic interventions.

Provides space and equipment for collaborative pilot projects between engineers and neuroscientists, workshops, training classes and product demonstrations as requested by members of Wu Tsai Neuro. Facility provides tissue culture suite with two biosafety cabinets, CO2 incubators, centrifuge and fluorescent microscope, in vivo procedure suite to allow animal surgeries, four curtained electrophysiological rig/microscope areas, two microscope rooms, -20C and -80C freezers and 4C cabinets for temporary sample storage.

MSKC is main gateway for Stanford faculty and students interested to study biological molecules using SLAC X-ray facilities and other major bioimaging facilities.

Provides scientific expertise and instrumentation for measurement of small molecules such as metabolites and lipids to ChEM-H and Stanford communities. Leverages expertise in mass spectrometry and allied techniques to understand biology of small molecules both metabolites and xenobiotics and to apply that understanding to advances in human health.

Service center and teaching lab focusing on molecular structural-functional studies. Jointly established by Sarafan ChEM-H, School of Engineering and SLAC National Accelerator Laboratory. Provides Stanford researchers with expertise, training and instruments for techniques in spectroscopy, bioimaging, crystallography, and scattering and diffraction.

Core for drug discovery and prototyping. Provides chemical probes for biological pathways and supports small molecule custom synthesis.Provides expertise in medicinal chemistry to biologists and clinicians at Stanford. Expertise in each step of drug development process, including hit generation, drug design and optimization, and clinical selection. Provides instrumentation to support synthesis, purification and analysis of small molecules.

Group of service centers (Nanofabrication, Electron & Ion Microscopy, X-ray & Surface Analysis and Soft & Hybrid Materials) that include Stanford Nanocharacterization Laboratory, Nanopatterning Cleanroom, Ginzton Microfab, and Soft and Hybrid Materials Facility. Core provides shared scientific instrumentation, laboratory facilities, and expert staff support.

Electronics Shop where researchers can access and share expertise to build specialized electronics. Offers support to electronic sub-system design for researchers across campus in departments of Physics, Applied Physics, Electrical Engineering, Psychology, Psychiatry and Behavioral Sciences and Bioengineering.Provides expertise from independently using tools to requesting turnkey solution.

One of four labs that are part of nano@stanford, under NSF National Nanotechnology Coordinated Infrastructure program. SNF includes cleanroom housing tools for device fabrication, satellite labs supporting Metal Organic Chemical Vapor Deposition,Experimental Fabrication methods and electronics shop for Systems Prototyping. SNF supports researchers in applications ranging from medicine and biology to fundamental physics and astronomy.

Interdisciplinary laboratory designed for study of human subjects.Lab resources are available to all Stanford GSB faculty and PhD students to support research that uses human participants, whether your focus is organizational behavior, behavioral marketing, political economics, or behavioral economics.Assists with research by programming study, posting study to one or more of the available subject pools, paying participants, running participants through experiments in the lab, or creating study materials.Engages with faculty members and doctoral students in preparing and carrying out human subjects research, both in-person laboratory experiments and online survey research.Provides expert consultation on behavioral experiments, and implementations of technology in behavioral research, such as eye-tracking, psychophysiology, and other specialized technology used in research with human subjects.

Provides resources and services to support business related research and teaching at Stanford University. As part of GSB Research Hub, helps foster scholarship, teaching, and innovation by committing to access, dissemination, creation, and preservation of information and knowledge.

The Human Immune Monitoring Center (HIMC) is designed to be a comprehensive source for immune monitoring services for clinical and translational studies. Goals of the HIMC include:
-To provide standardized, state-of-the art immune monitoring assays at the RNA, protein, and cellular level.
-To test and develop new technologies for immune monitoring.
-To efficiently archive, report, and mine data from immune monitoring studies, so as to increase the value of the data and to assist in biomarker discovery.
The HIMC uses an online database for integration of data from the standard HIMC assays, along with de-identified clinical and demographic data.

The Cell Sciences Imaging Facility (CSIF) provides high resolution, state-of-the-art technologies for imaging and analyzing the molecular and structural organization of cells and tissue. The facility offers sophisticated and demanding microscopy techniques (e.g. STORM, TIRF, SIM, FLIM, LLS, gSTED, airyscan, lightning, 2-photon live cell imaging, photo-activation and uncaging, array tomography, immuno-electron microscopy, high pressure freezing...) to Stanford University and industry researchers. The CSIF is organized into three imaging cores: the Fluorescence Microscopy Core (FMC) which houses multi-photon, confocal and deconvolution microscopes, codex services and image analysis software, the Electron Microscopy Core (EMC), which houses high resolution scanning and transmission electron microscopes and the Array Tomography Core (ATC) that provides complete array tomography services. The CSIF, in addition to its Director, Jon Mulholland, is staffed by 7 research associates that manage the instruments, provide expertise and training in electron and light microscopy.

DARC facility engages directly with faculty members, preparing large scale datasets, assisting with data analysis, and consulting on research design. Provides expertise on machine learning, text processing, and cloud services. DARC team also supports Yen compute environment, linux cluster designed for data intensive workloads in business research.

Beyond making available state-of-the-art, user-friendly facilities and services, the laboratory enables education, methods development, and new applications development, designed to meet the rapidly evolving needs of researchers.

Capabilities cover both small molecules and biomolecules: chemistry and drug discovery support, intact proteins, targeted quantitation, semi-targeted and targeted metabolomics, and proteomics including protein identification, protein network analysis, protein crosslinking studies, post-translational modifications, tissue analysis, quantitative proteomics, bioinformatics and more. Please contact SUMS to discuss these or other custom projects.

The Protein and Nucleic Acid (PAN) facility is a multifaceted biotechnology fee-for-service laboratory combining technology with expertise in genomics and protein analytics to support biological and biomedical research by providing a diverse array of services to not only the Stanford research community but also other non-profits and biopharmaceutical organizations. The services provided include:
- Gene Expression Analysis
- Microarrays (Full service)
- Real-time PCR (Full service or investigator use)
- Pyrosequencing using PyroMark technology for methylation analysis and sequence variation analysis(Full service or investigator use)
- Biomolecular Interaction Analysis (Surface Plasmon Resonance; Biacore)
- DNA Sequencing
- Oligonucleotide Synthesis
- Protein Sequencing
- Peptide Synthesis
- Protein Identification
- Mass Spectrometry
Each of our services is staffed and maintained by highly experienced and dedicated scientists. We can provide as much assistance as needed, from the initial study design through all the procedures needed for an experiment to the final interpretation and analysis of data. Our services include standard assays, as well as customized services. We are always interested in developing new assays, or adapting existing established assays to address a specific research question.

The Stanford Magnetic Resonance Laboratory (SMRL) is a core research service center within the Stanford University School of Medicine. The facility provides research instrumentation and expertise in the area of solution-phase, high resolution Nuclear Magnetic Resonance (NMR) spectroscopy.

The research focus of SMRL is primarily in the study of biological macromolecules, but also include other systems such as polymers, minerals, soils, and extracts.

Translational Applications Service Center (TASC) is a comprehensive shared resource center for conducting interdisciplinary studies to accelerate the pace of advances in patient therapy and diagnosis by enhancing basic research in the early stages of translation.

TASC provides expert technical assistance and support to support to obtain and analyze data from molecular , proteomic, and genomic research studies. It also offers its users PeggySue, a SimpleWestern platform from ProteinSimple: a state of the art nano-fluidic Immunoassay (NIA) technology for defining protein signatures and measuring proteomic response to targeted therapies in rare clinical specimens.


Services provided by TASC include:

* Charge (NIA) and Size-Based (SimpleWestern) Protein Separation Nano ImmunoAssay on PeggySue

* Assay development and optimization, set-up, data analysis

* Sample processing:
DNA/RNA/protein isolation from tissue, cells, paraffin block sections, fine needle aspirates (FNAs)

* Blood processing for NIA (PBMC isolation, serum, plasma)

* Cell culture services:
Culturing primary cells and cell-lines

* Assay development for detection and validation of Circulating Tumor Cells (CTCs) from blood.

* Cryopreservation and sample banking

* Technical consulting/individual training

The Neuroscience Microscopy Service (NMS) provides access to state-of-the-art light microscopy equipment (confocal, super-resolution, two-photon, and widefield microscopes). Image analysis workstations with Imaris, NeuroLucida, MatLab and Fiji software are also available. NMS provides one-on-one training on all equipment.

This facility provides a wide variety of commonly used software for biomedical researchers. Software categories includes microarray analysis, sequence analysis, pathway analysis, graphics, visualization, statistical analysis, and more. Linux/Solaris servers and a multi-terabyte disk array are also available.