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Washington University School of Medicine
St. Louis, MO 63110
United States of AmericaBrian Faddis
Last Updated: 10/26/2012
The Center provides coordinated evaluation of function, anatomy and pathology of research models of the auditory and vestibular systems and promotes related translational and clinical research. Four subcores (Functional Testing, Histology, Microscopy & Digital Imaging, and Clinical/Translational Research) provide services to both member and non-member researchers. The RCAVS was designed to conduct rapid functional and anatomical evaluations of new research models that might impact the auditory and vestibular sciences. New genetic manipulations are regularly screened for functional deficits and the anatomic correlates of those deficits. Due to the sensitivity of auditory and vestibular testing, any models suspected to impact development/growth, neural/synaptic transmission and aging are encouraged to consider evaluation by our center.
The RCAVS Functional Testing Core provides state-of-the-art auditory and vestibular functional testing for appropriate animal models of development, aging, disease and sensory function. The core works seamlessly with Histology and Imaging Cores to provide anatomical correlates of functional results when desired.
Services are offerred outside of Washington University School of Medicine
Consulting is offerred outside of Washington University School of Medicine
Four sub-cores provide seamless integration of services to allow a rapid functional and anatomical evaluation of mouse models for auditory and vestibular research. Very briefly these cores and their services include:
1. Functional Testing Core--ABR, DPOAE, VOR and single unit recording;
2. Histology Core--wide variety of tissue processing for light and electron microscopy;
3. Microscopy & Digital Imaging Core--confocal microscopy, digital SEM and TEM, and image analysis;
4. Clinical & Translational Research Core--IRB, data management and biostatistical support
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