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All Facilities >> Black Hills State University >> South Carolina College of Pharmacy Microarray Core Facility (Genomics / Genome Analysis and Technologies)
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Dept. of Pharmaceutical and Biomedical Sciences, University of South Carolina
715 Sumter Street, CLS 617
Columbia, SC 29208
United Stateshttps://www.sc.edu/study/colleges_schools/pharmacy/research_and_practice/research_centers_and_facilities/microarray_core_facility/index.phpcite this facility
Dr. Diego Altomare
Last Updated: 05/19/2025
Services Provided: The USC Microarray Core Facility (formerly the SCCC DNA Microarray Facility) can conduct RNA quality control, amplification and labeling; conduct array hybridization, scanning and data analysis, and assist customers in all aspects of the design and performance of microarray experiments, using Agilent (pre-made and custom) and Affymetrix arrays. In addition, the facility provides support for quantitation and quality assessment of DNA, RNA and protein on an Agilent 2100 Bioanalyzer.
Hybridization
We provide extensive on site training and support for Agilent and Affymetrix Hybridization Oven users.
Scanning and Data Analysis
Support is provided for microarray scanning and for data analysis with a variety of software packages for both Agilent and Affymetrix platforms.
Analysis of RNA, DNA, Proteins and Cells
Quantity and quality of your RNA, DNA, proteins and cells are determined with the help of an Agilent 2100 Bioanalyzer.
Services are offerred outside of Black Hills State University
Consulting is offerred outside of Black Hills State University
The Facility includes: (1) a Packard Bioscience Biochip Arrayer. Based on Ink jet technology the arrayer has 4 piezoelectric capillary tips that achieve extremely accurate non-contact dispensing. When in operation the glass capillaries of PiezoTip dispensers cruise over a glass slide or other substrate at a height of 500 microns, dispensing droplets of 350 picoliters to a target with a X/Y positional accuracy of 10 microns. The Biochip Arrayer is ideal for the production of extremely high quality arrays of up to about 2,000 spots/slide, custom-made to satisfy the requirements of individual investigators. The arrayer also has enormous flexibility in terms of substrate and spotted product, being able to spot on a variety of materials, and not only nucleic acids but also proteins, peptides, and even bacterial cells; (2) an automatic hybridization system in the form of a 12 position GeneTac HybStation. Up to six protocols can be run simultaneously, which allows for hybridization with uniform, reproducible results and minimal handling of solutions and slides; (3) a hybridization oven and rotator, which are optimized for the hybridization of high-density arrays from Agilent Technologies and a Maui Hybridization System; (4) a Perkin Elmer confocal laser scanner Scan Array Express HT is available for microarray scanning using up to 5 lasers which allow for the detection and quantification of signal from virtually all commercially available fluorochromes including the commonly used Cy3 and Cy5; (5) an Agilent Technologies 2100 Bioanalyzer that allows for the rapid assessment of RNA quality (software available with this instrument assigns an RNA Integrity Number (RIN) to the samples, based on various parameters of RNA integrity; and (6) a powerful 8-tip automated liquid handling system – the Perkin Elmer Multiprobe II - to ensure accuracy and reliability in the handling and arraying of oligonuclotides and cDNAs prior to spotting.
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https://coremarketplace.org/?FacilityID=234Institution
Institution ROR ID: https://ror.org/03fng6237Keywords:
USEDit, ABRF, RNA quality control, amplification and labeling, array hybridization, scanning and data analysis, microarray experiments
Resource Type:
service resource, access service resource, core facility
Citation:
University of South Carolina at Columbia College of Pharmacy Microarray Core Facility (RRID:SCR_022211)
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Analysis Workstations
Bioluminsecence Imaging
Brightfield Microscopy
Cell Culture
Cell Imaging
Clinical Imaging - Small Animal (luminescence/fluorescence)
Clinical Imaging - Small Animal (X-ray, Ultrasound, microCAT, MRI)
Confocal Microscopy
Digital PCR
Electron Microscopy
FACS Cell Sorting
Flow Cytometric Analysis
Flow Cytometry
H&
E Staining
Histology
Image Aquisition
Immunofluorescence
Immunohistochemistry
In-vivo Imaging
Laser Capture Microdissection
Lattice Lightsheet
Light-sheet Microscopy
Live Cell Imaging
Microarray
MicroCT
Microscopy
Molecular Imaging
Multiphoton Microscopy
Negative Staining For TEM
Optical Imaging
Paraffin Embedding
Plate Reader
Real-time qPCR
Scanning Electron Microscopy
Staining
Tissue Culture
Transmission Electron Microscopy
Ultrasonic Imaging
Biotechnology
Austin Worden
6311 Garners Ferry Rd
Building 1, Room B60
Columbia, SC 29209 - United States
RRID:SCR_024955
Mission: By providing state-of-the-art biomedical instrumentation, the IRF seeks to facilitate the expansion of scientific knowledge and discovery in the USC School of Medicine Columbia and main campus research environments.
Purpose: As an integral component of the research and teaching mission of the University of South Carolina School of Medicine, the IRF houses several major pieces of state-of-the-art biotechnological equipment that provide investigation ranging from single cell and molecular level analysis to whole animal imaging. Additionally, the IRF maintains a full range of ancillary equipment available for sample preparation, image enhancement, and data analysis.
This facility provides services outside its institution
This facility provides consulting outside its institution
10/10/2024
Genotyping
Library Services
Sequencing - DNA Sequencing
Sequencing - Next Generation Sequencing (NGS)
Dr. Cynthia Anderson
1200 University Blvd, Unit 9008
Spearfish, SD 57799-9008 - United States of America
http://www.bhsu.edu/Default.aspx?alias=www.bhsu.edu/westcore
The Western South Dakota DNA Core Facility (WestCore) was established in 2003 as part of the South Dakota Biomedical Research Infrastructure Network (SD-BRIN). We complement the Proteomics and Genomics BRIN core facilities.
Our primary services include nucleic acid sequencing, genotyping, marker development and library construction. Priority is given to SD-BRIN/INBRE research, but services are also provided to non-BRIN/INBRE university researchers as well as government agencies and some private organizations.
Westcore is a fully staffed laboratory with automated DNA instrumentation, and has a federally approved quality management plan.
This facility provides services outside its institution
This facility provides consulting outside its institution
04/04/2017
Cell Imaging
Cell Sorting
Confocal Microscopy
Electron Microscopy
Flow Cytometric Analysis
Histology
Immunohistochemistry
Laser Capture Microdissection
Microscopy
Optical Imaging
Ultrasonic Imaging
Bob Price
School of Medicine
6439 Garner's Ferry Road
Columbia, SC 29208 - United States of America
The Instrumentation Resource Facility (IRF) is an integral component of the research and teaching mission of the University of South Carolina School of Medicine (USC SOM). Located within the facility are several major pieces of state-of-the-art biomedical research equipment that provide techniques ranging from whole animal through single cell imaging to analysis at the molecular level. The IRF also houses a full range of ancillary equipment that is available for sample preparation. In addition to serving as a resource for acquisition of primary data, the IRF also has the capacity for image enhancement and related data analysis.
The mission of the IRF is to provide state-of-the-art biomedical research instrumentation for use in the USC SOM and USC main campus research environments. As time and resources permit, outside use of the facility is also permitted and encouraged. Technical assistance and training are available in most areas of research sponsored in the IRF. The flowchart below presents broad categories of instrumentation that are available in the IRF and subsequent pages present specific information concerning instrument configurations, training and rules for the use of instruments, the appropriate IRF staff to contact for the use of various pieces of equipment, and pricing.
This facility provides services outside its institution
This facility provides consulting outside its institution
05/08/2013
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