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All Facilities >> University of Rochester >> UR Genomics Research Center (URGRC) (Genomics / Genome Analysis and Technologies)
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601 Elmwood Avenue
Wilmot Cancer Center, 3-0771
Rochester, NY 14642
United Stateshttps://www.urmc.rochester.edu/research/rochester-genomics-center.aspxcite this facility
John Ashton
Last Updated: 05/19/2025
The UR Genomics Research Center (GRC), located at the James P. Wilmot Cancer Institute, provides core laboratory support, technical consultation, assistance with experimental design and data analysis for investigators using high-throughput genomic sequencing, genotyping and gene expression in their research programs.
The URGRC currently provides support for RNA-Seq, ATAC-seq, ChIP-Seq, Single Cell RNA-seq, Spatial Transcriptomics, Exome/Genome sequencing, Whole Genome and Reduced Representation Bisulfite Sequencing (WGBS, RRBS), 16S rRNA Sequencing, Small RNA-Seq, Metatranscriptomics, qRT-PCR, processing of RNA/DNA, as well as custom applications and approaches. Bioinformatic analysis support is also available.
Services are offerred outside of University of Rochester
Consulting is offerred outside of University of Rochester
Sequencing - Capillary Sequencing
Sequencing - Next Generation Sequencing (NGS)
10X Genomics Chromium Plus Genetic Analyzer
Genetic analyzer, referred to as Chromium Controller for combining large partition numbers with a diverse barcode library to generate >100,000 barcode-containing partitions. [Product Link]
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Agilent 2100 Bioanalyzer Instrument
This Bioanalyzer Instrument is used for sample quality control of biomolecules. [Product Link]
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Agilent 5300 Fragment Analyzer System
Fragment Analyzer System can separate up to 48 or 96 samples in parallel. [Product Link]
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Covaris E220evolution Focused-Ultrasonicator
Focused ultrasonicator that enables multi sample, batch preparation, capable of processing wide range of sample types and volumes. [Product Link]
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Eppendorf 5075 epMotion Automated Liquid Handling System
System provides precise, accurate alternative to time-consuming manual pipetting and liquid handling tasks. The combination of accelerated operational speed, new software & hardware features and an increased number of worktable positions make the systems best for and flexible laboratory use across a wide range of liquid handling applications. To ensure easy and consistent use, epMotion 5075 employs both Eppendorf's established epBlue software and an new software assistant concept. This supports the programming of applications and ensures that all users can use the system with only initial training. In addition, novel features such as a new CleanCap option, including UV light decontamination and a HEPA filter for purified air, offer new standards of decontamination and sample safety. This is supported even further by an optical sensor that checks labware, liquid levels and tip counts and type at the start of each cycle, hugely decreasing any risk of error during the run. [Product Link]
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Illumina MiSeq System
Access focused applications such as targeted resequencing, metagenomics, small genome sequencing, targeted gene expression profiling, and more. MiSeq reagents enable up to 15 Gb of output with 25 million sequencing reads and 2 × 300 bp read lengths. [Product Link]
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Illumina NextSeq 550 System
With tunable output and high data quality, it provides flexible power you need for whole genome, transcriptome, and targeted resequencing plus ability to scan microarrays including Infinium MethylationEPIC BeadChip and other select BeadChips. [Product Link]
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Illumina NovaSeq 6000 Sequencing System
Unleashes groundbreaking innovations that leverage our technology Now you can get scalable throughput and flexibility for virtually any sequencing method, genome, and scale of project. [Product Link]
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PerkinElmer Sciclone G3 liquid handling robot
Agilent 2200 TapeStation System
Sage Science PippinHT
ABI QuantStudio 12K Flex Real-Time PCR System with autoloader and microfluidic card module
No publications have been associated with this facility
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https://coremarketplace.org/?FacilityID=400Institution
Institution ROR ID: https://ror.org/022kthw22Keywords:
Genomic sequencing, genotyping, gene expression, ABRF, USEDit
Resource Type:
access service resource, core facility, service resource
Citation:
University of Rochester Genomics Research Center Core Facility (RRID:SCR_012359)
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Consultation
Consultations
Data Analysis
Data Analysis And Interpretation
Data Processing
Data Processing And Interpretation
HPLC
HRAM Mass Spectrometry
Label Free Quantitative Proteomics
Labeled Quantitative Proteomics -TMT And Other Labeling
Mass Spectrometry
Mass Spectrometry - Proteins And Peptides
Mass Spectrometry - Small Molecules
Nano-LC-MS -complex Mixtures
Phosphoproteomics
Proteomics
Proteomics Analysis
Quantitative Proteomics - TMT
Sample Preparation
SDS-PAGE
TMT-Quantitation
Training
Untargeted Mass Spectrometry
Proteomics
Kevin Welle, Technical Director
601 Elmwood Avenue
Rochester, NY 14642 - United States
https://www.urmc.rochester.edu/research/mass-spectrometry.aspx
RRID:SCR_023106
The Mass Spectrometry Resource Laboratory (MSRL) provides instrumentation and technical expertise to local researchers seeking to conduct MS-based protein or small molecule assays.
Staff within the MSRL provide assistance with project design, sample preparation, collection and interpretation of mass spectrometric data.
Common analyses include the identification of unknown proteins, characterization of protein complexes, mapping of post-translational modifications (PTMs) and quantitation of peptides and small molecules from a range of sample types, including complex clinical matrices, tissue extracts and cell lysates.
Specialized MS instrumentation operated and maintained by the core include a Thermo Orbitrap Astral, a timsTOF Ultra, and a Thermo Q Exactive Plus Hybrid Quadrupole-Orbitrap. In addition, the laboratory has access to a variety of automated database searching software including Proteome Discoverer and DIA-NN.
This facility provides services outside its institution
This facility provides consulting outside its institution
12/10/2024
Assay Development
Biochemical Analysis
Consultations
Data Analysis
Data Processing
Discovery Science
HPLC
HRAM Mass Spectrometry
LC-MS
Lipidomics
Mass Spectrometry
Mass Spectrometry - Small Molecules
Metabolomics
Metabolomics Platform
Sample Preparation
Sample Preparations And Metabolic Quenching
Small Molecule Characterization
Stable Isotope Tracing
Training
Untargeted Mass Spectrometry
Metabolomics
Kevin Welle
601 Elmwood Avenue
Medical Center 3-6821
Rochester, NY 14642 - United States
RRID:SCR_024998
Specializing in metabolomic analysis.
This facility provides services outside its institution
This facility provides consulting outside its institution
02/07/2024
Biorepository
Bioshipping
Cold Storage
Christopher Lane
601 Elmwood Avenue
Rochester, NY 14642 - United States
https://www.urmc.rochester.edu/research/cold-storage-core.aspx
RRID:SCR_023197
The Cold Storage Core provides a controlled environment designed for the long-term storage of clinical/research materials in -20ºC or -80ºC freezers and in liquid nitrogen freezers.
This facility provides services outside its institution
This facility provides consulting outside its institution
01/25/2023
Analysis Workstations
Assay Development
Assays and Measurements
Automated Immunoassay Platforms
Cell Imaging
Cell Sorting
Clinical Trial Support
Computational - Application Development
Computational - Bioinformatics
Consultation
Consultations
CyTOF
Cytokine Assays
Data Analysis
Data Analysis And Interpretation
Data Visualization
DNA Analysis
FACS Cell Sorting
Flow Cytometric Analysis
Flow Cytometry Data Analysis
Imaging Flow Cytometry
Imaging Flow Cytomtry
Immune Monitoring
Immunoassay
Light Scattering
Luminex Bead Based Cytokine Assays
Luminex Services
Mass Cytometry
Multi-color Flow Cytometry
Nanosight Nanoparticle Analysis
Protocol Development
RNA Flow Cytometry
Spectral Flow Cytometry
Staining
Training
Flow Cytometry
Matthew Cochran
601 Elmwood Avenue
Rochester, NY 14642 - United States
RRID:SCR_012360
The URMC Flow Cytometry Resource is equipped with a wide array of instrumentation that is rarely matched the world over. This includes 8 traditional analytical cytometers, two full spectrum cytometers, 3 cell sorters, 2 imaging cytometers, a small(nano) particle detection system, a Metabolomics instrument, a BioPlex200, and a mass cytometer.
This facility provides services outside its institution
This facility provides consulting outside its institution
01/23/2023
Martin Pavelka, PhD
601 Elmwood Avenue
University of Rochester Medical Center
Rochester, NY 14642 - United States
RRID:SCR_023178
The Biosafety Level 3 (BSL3) core facility is available for use by any researcher at the university whose work requires the manipulation of biological agents that may cause serious or potentially lethal disease as a result of exposure by the inhalation route.
This facility does not provide services outside its institution
This facility does not consult outside its institution
01/20/2023
Biological photography/Photomicrography
Cell Imaging
Consultation
Consultations
Cryo-Electron Microscopy
Electron Microscopy
Image Aquisition
Immuno Electron Microscopy
Microscopy
Microtomy/Electron
Sample Preparation
Scanning Electron Microscopy
Transmission Electron Microscopy
Microscopy (Electron, Fluorescence, Optical)
Karen Bentley
601 Elmwood Avenue
Box 626
Rochester, NY 14642 - United States
https://www.urmc.rochester.edu/research/electron-microscope.aspx
RRID:SCR_012366
The Electron Microscopy Resource supports ultra-structural interrogation of tissues, biologic solutions and nanomaterials for investigators utilizing transmission electron microscopy (TEM), scanning electron microscopy (SEM) and cryo-TEM.
This facility provides services outside its institution
This facility provides consulting outside its institution
01/19/2023
Cell Imaging
Confocal Microscopy
Data Analysis
Laser Capture Microdissection
Microscopy
Molecular Imaging
Multiphoton Microscopy
Optical Imaging
Linda Callahan
575 Elmwood Ave
University of Rochester Medical Center
Rochester, NY 14621 - United States of America
http://www.urmc.rochester.edu/confocal-conventional-microscopy/index.cfm
RRID:SCR_023177
This is URMCs resource for Conventional (Brightfield) microscopy and confocal microscopy.
This facility provides services outside its institution
This facility provides consulting outside its institution
01/20/2023
Assays and Measurements
Blood Processing
Cell Culture
Cell Imaging
Cell Sorting
Computational - Application Development
Flow Cytometric Analysis
Imaging Flow Cytomtry
Mass Cytometry
Outreach
Protocol Development/Clinical Trial Coordination
Spectral Flow Cytometry
Tissue Culture
Sally A. Quataert
David H. Smith Center for Vaccine Biology and Immunology
601 Elmwood Ave., P.O. Box 609
Rochester, NY 14642 - United States of America
https://www.urmc.rochester.edu/rochester-human-immunology-center.aspx
RRID:SCR_018670
Modern immunological techniques are sophisticated and powerful, and can be applied effectively to many basic and clinical projects. However, it is difficult for any one investigator to become expert in all of these complex techniques and expertise in immunology is typically spread across different Departments. The Human Immunology Center (HIC) within the David H. Smith Center for Vaccine Biology and Immunology has been established to acquire, refine and develop expertise in cutting-edge techniques and to support applications in Human Immunology research. The HIC is designed with capabilities to enhance multi-disciplinary research initiatives catalyzing key clinical and basic immunology research in vaccines, HIV/AIDS, autoimmunity, allergy/asthma, transplantation as well as cancer immunology.
This facility provides services outside its institution
This facility provides consulting outside its institution
01/07/2020
Cell Imaging
Cell Sorting
Flow Cytometric Analysis
Timothy Bushnell
601 Elmwood Ave, Box 703
MRBX 1-11314
Rochester, NY 14642 - United States of America
The goal and mission of the Center for Pediatric Biomedical Research flow facility is to develop, validate and implement polychromatic flow cytometric protocols to support and enrich the research programs of CPBR faculty. This flow facility will focus on the development of experimental and unique protocols to breach previously unexplored avenues of experimentation with flow cytometry.
Our current instrumentation includes:
(1) a 3-laser (488, 633 and 355 nm) 12-color LSR-II with high throughput sampler system.
(2) a 3-laser (488, 633 and 405 nm) 13-color FACSAria cell sorter with ACDU system. This system is validated for BSL-2 sorting.
(3)a 3-laser (488, 653 and 405 nm) Amnis Imagestream imaging cytometer with extended depth of focus module.
Training, consulting and collaboration with investigators (internal and external)is available.
This facility does not provide services outside its institution
This facility does not consult outside its institution
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