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Mass Spectrometry Resource Laboratory (Proteomics)

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Primary Contact:

Brad Smith

Last Updated: 01/19/2023

Facility RRID

RRID:SCR_023106

Facility Details

The Mass Spectrometry Resource Laboratory (MSRL) provides instrumentation and technical expertise to local researchers seeking to conduct MS-based protein or small molecule assays.

Staff within the MSRL provide assistance with project design, sample preparation, collection and interpretation of mass spectrometric data.

Common analyses include the identification of unknown proteins, characterization of protein complexes, mapping of post-translational modifications (PTMs) and relative quantitation of peptides and small molecules from a range of sample types, including complex clinical matrices, tissue extracts and cell lysates.

Specialized MS instrumentation operated and maintained by the core include a Fusion Lumos Tribrid Orbitrap and a Thermo Q Exactive Plus Hybrid Quadrupole-Orbitrap. In addition, the laboratory has access to a variety of automated database searching software as well as resources to facilitate discovery-based proteomics projects.

Facility Policies

Services are offerred outside of University of Rochester Medical Center

Consulting is offerred outside of University of Rochester Medical Center