The CoreMarketplace: HUC-Genomics

The Genomics Core Facility provides services using several different next-generation sequencing platforms. Applications supported include:

Whole-genome and transcriptome sequencing of non-model organisms
Amplicon sequencing for metagenomic studies
Differential expression analysis of mRNA and miRNA
Degradome sequencing
ChIP and RIP sequencing

Facility Policies

Services are offerred outside of Pennsylvania State University

Consulting is offerred outside of Pennsylvania State University

(To see more facility information, click the in the upper right)

Services offered:

10x Genomics

DNA Analysis

Full Genome CDNA Screening

Genomics

Genotyping

Metagenomics Analysis

Sequencing - Capillary Sequencing

Sequencing - DNA Sequencing

Sequencing - Next Generation Sequencing (NGS)

Single-cell Sequencing

Whole Exome Sequencing

Whole Genome Sequencing

Facility Equipment

Illumina MiSeq System

Access focused applications such as targeted resequencing, metagenomics, small genome sequencing, targeted gene expression profiling, and more. MiSeq reagents enable up to 15 Gb of output with 25 million sequencing reads and 2 Ã— 300 bp read lengths. [Product Link]

RRID:SCR_020134

cite this instrument

Illumina NextSeq 1000 and NextSeq 2000 Sequencing Systems

Benchtop sequencers that allow you to explore new science across variety of current and emerging applications, with higher efficiency and fewer restraints. [Product Link]

RRID:SCR_020140

cite this instrument

PacBIO SEQUEL IIe

No additional equipment has been listed

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Publications

Publications associated with this facility (Click To View):

1.) Ortigas-Vasquez A, Bowen CD, Renner DW, Baigent SJ, Zhang Y, Yao Y, Nair V, Kennedy DA, Szpara ML (2025 Feb 11). High-Fidelity Long-Read Sequencing of an Avian Herpesvirus Reveals Extensive Intrapopulation Diversity in Tandem Repeat Regions bioRxiv, (), 2025.02.10.637388. . PMCID: 11844383.

2.) Rios KT, McGee JP, Sebastian A, Gedara SA, Moritz RL, Feric M, Absalon S, Swearingen KE, Lindner SE (2025 Jan 8). Widespread release of translational repression across Plasmodium’s host-to-vector transmission event PLOS Pathogens, 21(1), e1012823. . PMCID: 11750109.

3.) Nichols RG, Davenport ER (2024 Dec 16). Clade-specific long-read sequencing increases the accuracy and specificity of the gyrB phylogenetic marker gene mSystems, 10(1), e01480-24. . PMCID: 11748558.

4.) Quinlan GM, Hines HM, Grozinger CM (2024 Dec 13). Leveraging Transcriptional Signatures of Diverse Stressors for Bumble Bee Conservation Molecular Ecology, 34(3), e17626. . PMCID: 11754722.

5.) Locatelli NS, Kitchen SA, Stankiewicz KH, Osborne CC, Dellaert Z, Elder H, Kamel B, Koch HR, Fogarty ND, Baums IB (2024 Nov 20). Chromosome-level genome assemblies and genetic maps reveal heterochiasmy and macrosynteny in endangered Atlantic Acropora BMC Genomics, 25(), 1119. . PMCID: 11577847.

6.) Seemiller LR, Goldberg LR, Sebastian A, Siegel SR, Praul C, Zeid D, Albert I, Beierle J, Bryant CD, Gould TJ (2024 Nov). Alcohol and fear conditioning produce strain-specific changes in the dorsal hippocampal transcriptome of adolescent C57BL/6J and DBA/2J mice. Alcohol, clinical & experimental research, 48(11), 2022-2034. doi: 10.1111/acer.15440. PMID: 39279663.

7.) Locatelli NS, Baums IB (2024 Aug 22). Genomes of the Caribbean reef-building corals Colpophyllia natans, Dendrogyra cylindrus, and Siderastrea siderea bioRxiv, (), 2024.08.21.608299. . PMCID: 11370458.

8.) McKinley LN, Meyer MO, Sebastian A, Chang BK, Messina KJ, Albert I, Bevilacqua PC (2024 Jul 11). Direct testing of natural twister ribozymes from over a thousand organisms reveals a broad tolerance for structural imperfections. bioRxiv : the preprint server for biology, (), . . PMID: 39026743.

9.) Kulesza E, Thomas P, Prewitt SF, Shalit-Kaneh A, Wafula E, Knollenberg B, Winters N, Esteban E, Pasha A, Provart N, Praul C, Landherr L, dePamphilis C, Maximova SN, Guiltinan MJ (2024 Jun 26). The cacao gene atlas: a transcriptome developmental atlas reveals highly tissue-specific and dynamically-regulated gene networks in Theobroma cacao L. BMC plant biology, 24(1), 601. . PMID: 38926852.

10.) Pearce DL, Edson JE, Jennelle CS, Walter WD (2024 May 17). Evaluation of DNA yield from various tissue and sampling sources for use in single nucleotide polymorphism panels Scientific Reports, 14(), 11340. . PMCID: 11101418.

11.) Rios KT, McGee JP, Sebastian A, Moritz RL, Feric M, Absalon S, Swearingen KE, Lindner SE (2024 Feb 1). Global Release of Translational Repression Across Plasmodium’s Host-to-Vector Transmission Event bioRxiv, (), 2024.02.01.577866. . PMCID: 10862809.

(To see more facility information, click the in the upper right)

Associations

ABRF

Association of Biomolecular Resource Facilities

NERLSCD

Northeast Regional Life Science Core Directors

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Metadata

Links

All the links listed resolve to this core profile

https://coremarketplace.org/?FacilityID=1779
https://coremarketplace.org/RRID:SCR_023645

Institution

Institution ROR ID: https://ror.org/04p491231

SciCrunch Data Imports (data maintained by https://scicrunch.org)

Keywords:

USEDit, ABRF, Whole-genome and transcriptome sequencing of non-model organisms, Amplicon sequencing for metagenomic studies, Differential expression analysis of mRNA and miRNA, Degradome sequencing, ChIP and RIP sequencing,

Resource Type:

access service resource, core facility, service resource

Citation:

Pennsylvania State University Huck Institutes of the Life Sciences Genomics Core Facility (RRID:SCR_023645)

HUC-Genomics

Primary Contact:

Facility RRID

Facility Details

Facility Policies

(To see more facility information, click the in the upper right)

Services offered:

Facility Equipment

(To see more facility information, click the in the upper right)

Publications

(To see more facility information, click the in the upper right)

Associations

ABRF

NERLSCD

(To see more facility information, click the in the upper right)

Metadata

SciCrunch Data Imports (data maintained by https://scicrunch.org)

Facility Profile QR Code (links to this profile)

(To see more facility information, click the in the upper right)

Contact Craig Praul

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HUC-Genomics

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