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All Facilities >> Texas A&M University >> Laboratory for Synthetic-Biologic Interactions
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Justin Smolen
Last Updated: 10/10/2024
The Laboratory for Synthetic-Biologic Interactions (LSBI) is a research facility housed in the Department of Chemistry. The LSBI is designed to be a multi-user laboratory supporting major research initiatives within the Chemistry Department, the university and extending to the broader academic and industrial scientific communities. Fifteen instruments are currently available on a fee-for-use basis, and others may be made available on case-by-case considerations.
Services are offerred outside of Texas A&M University
Consulting is offerred outside of Texas A&M University
Clinical Imaging - Small Animal (luminescence/fluorescence)
Confocal Microscope With FCS/FLIM Capabilities
Data Analysis And Interpretation
Data Processing And Interpretation
Horiba FluoroMax 4 Spectrofluorometer
FluoroMax family, with its all reflective optics and photon counting was the first to bring the sensitivity of a modular fluorometer to a tabletop fluorescence instrument. It's a compact spectrofluorometer, yet offers the ultimate sensitivity in fluorescence investigations as well as features not found in most table-top fluorescence detection systems. The FluoroMax series consists of the FluoroMax-4, the latest generation of the original, high performance tabletop fluorometer, which offers extended performance with detection of emission spectra out to 1700 nm and (TCSPC) Time Correlated Single Photon Counting lifetime measurements as short as 25ps. [Product Link]
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Molecular Devices SpectraMax M5 Multimode Plate Reader
Microplate Reader delivers single mode reader performance and can be equipped to read volumes as low as 2uL in one multimode reader package. The dual monochromator optics allow the widest range of applications to be utilized for bioresearch and drug discovery applications, all without the need to change filters. For fluorescence intensity, time resolved fluorescence, and fluorescence polarization assays, the SpectraMax M5 Microplate Reader optical design provides the highest level of flexibility. Users can select from top or bottom read modes for improved sensitivity for solution and cell-based assays. Assays can be better optimized by scanning across a range of wavelengths in increments as small as 1 nm. Up to 4 wavelength pairs can be read in one protocol for endpoint and kinetic measurements, allowing for fast setup of FRET and TR-FRET assays. For luminescence, the SpectraMax M5 Microplate Reader utilizes a dedicated luminescence photomultiplier tube (PMT), providing the user the maximum signal and lowest background possible for glow luminescence reporter gene assays. The SpectraMax M5 utilizes a single monochromator design for UV/VIS Absorbance, allowing the user to maximize sensitivity and tunability, and also uses patented PathCheck Pathlength Measurement Technology: the only temperature independent pathlength correction for microplates. The M5 can read volumes down to 2uL with the uMax Low Volume Plate. [Product Link]
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Olympus FV1000 Confocal Microscope
Next generation imaging system designed for high resolution, confocal observation of both fixed and living cells.FV1000 offers advances in confocal system performance while providing the speed and sensitivity required for live cell imaging with minimal risk of damage to living specimens.In addition, the FV1000 offers a revolutionary synchronized laser scanning system called the SIM Scanner. While one laser stimulates, the second laser simultaneously provides high-resolution imaging. This coordination of laser stimulation and imaging makes the FV1000 an ideal choice for FRAP, FLIP and photoactivation. [Product Link]
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Olympus IX70 Inverted Fluorescence Tissue Culture Microscope
Inverted fluorescence tissue culture microscope capable of imaging specimens in brightfield, darkfield, phase contrast, hoffman modulation contrast, fluorescence, and differential interference contrast modes. [Product Link]
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Bruker Bruker LUMOS II Imaging Micro-FTIR
Micro-FTIR system for rapid hyperspectral imaging in the mid-IR range. Equipped with FPA detectors for rapid imaging in transmission, reflectance, and ATR modes. Ideal for microplastics detection and classification, material chemical mapping at the micron scale, and mapping chemical differences across biological tissues. Capable of automation with Python to increase throughput and reduce cost of operation.
Shimadzu IR Prestige 21 FTIR
Shimadzu AIM 8800 FTIR Microscope
Biolin Attension Tensiometer
Mettler Toledo DMA 1
ATS Rheosystems Black Pearl Viscometer
Biolin Q-Sense QCM-D
B&W Tek i-Raman
PicoQuant FluoTime 100 TCSPC
Zetasizer Nano ZS DLS
Shimadzu UV-2550
Bruker Xtreme 4MP
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https://coremarketplace.org/?FacilityID=1358Institution
Institution ROR ID: https://ror.org/01f5ytq51Keywords:
USEDit, ABRF, synthetic biologic interactions
Resource Type:
access service resource, core facility, service resource
Citation:
Texas A and M University Laboratory for Synthetic Biologic Interactions Core Facility (RRID:SCR_022287)
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