The Genomics Core hopes to provide a centralized resource working to take the difficulty out of Next Generation Sequencing projects for both novice and experienced users alike. To accomplish this we provide assistance in all facets of experimentation from design to data analysis including grant and manuscript preparations. We are a facility that offers NGS, Sanger, Informatics and Genotyping services based off of the Illumina platform.

The Case Center for Imaging Research (CCIR) exists to help further the study of imaging. Within the CCIR, the Imaging Research Core provides a comprehensive suite of preclinical and clinical imaging instrumentation and techniques developed in-house by our leading imaging scientists.

The Core services the CWRU and University Hospitals research communities, researchers and industry partners throughout University Circle and Northeast Ohio, and across the country.

The Imaging Research Core offers the expertise, infrastructure, and environment that can help turn your research into a reality.

Engineers in the Polymer Core work closely with physicians, surgeons, and researchers throughout Cleveland Clinic to provide extensive services on medical device design, prototype and evaluation. We help our inventors to “prove the concept” of their novel inventions, which will ultimately benefit our patients. We also help research groups at Lerner Research Institute to fabricate or repair research instruments, which are not commercially available, such as cell culture fixture, test instruments, etc.

Electronics Core is electronics design, development and repair facility which specializes in proof-of-concept design and prototyping, and early stage development of medical devices and laboratory research instrumentation. Services include system design, schematic capture, printed circuit board layout, board fabrication, assembly and testing.

Core provides biomechanical testing of biological structures and biomaterials. Allows investigators to conduct research of mechanical properties of existing biological structures and constructs, as well as to quantify potential for new technologies and clinical advancements. Robotic simulators are built around the simVITRO software platform and are designed for in vitro simulation of major joints including knee, spine, foot, ankle, hip, shoulder, elbow, wrist and more. Provides testing capabilities for range of biomechanical modalities and will offer expert advice and support for development of new test protocols, innovative techniques for instrumentation and data collection. Modalities include tissues, joints, and multi-articular units, such as foot or spine segments.

Mechanical Core provides variety of fabrication, customization and repair services for mechanical devices and equipment. Offers precision machining of metals and plastics, welding of structural and exotic metals, instrument refurbishing and mechanical repair.

Core provides mechanical and biomedical engineering expertise and services. Specializes in early-stage development and proof-of-concept prototypes. Utilizes 3D modeling, 3D printing, nitinol shape setting, and laser cutting to design and fabricate custom medical devices, test fixtures, and CT/MRI-based anatomy models.

Core provides investigators with resource for quantitative studies of cells, extracellular vesicles, and single-cell gene transcriptome analyses. Offers sample acquisition and analysis, cell sorting, and consultation for experimental design, interpretation and troubleshooting.

Core offers services in areas of peptide synthesis, peptide modification, purification and quality analysis, N-terminal protein sequencing by Edman degradation, and biomolecular interaction analysis and equilibrium and kinetic measurements.