The CoreMarketplace: Genomic Sequencing and Analysis Facility

The GSAF is a full service genomics core, we offer consultations, Next Generation Sequencing and library prep, single cell and spatial transcriptomics and methylation arrays.

Facility Policies

Services are offerred outside of The University of Texas at Austin

Consulting is offerred outside of The University of Texas at Austin

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Services offered:

10x Genomics

RNA Integrity

Sequencing - DNA Sequencing

Sequencing - Next Generation Sequencing (NGS)

Facility Equipment

No additional equipment has been listed

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Publications

Publications associated with this facility (Click To View):

1.) Nice CC, Bell KL, Gompert Z, Lucas LK, Ott JR, Tovar RU, Crump P, Diaz PH (2025 Jan 9). Extensive Admixture Among Karst‐Obligate Salamanders Reveals Evidence of Recent Divergence and Gene Exchange Through Aquifers Ecology and Evolution, 15(1), e70785. . PMCID: 11717725.

2.) Yao J, Xu H, Ferrick-Kiddie EA, Nottingham RM, Wu DC, Ares M Jr, Lambowitz AM (2024 Sep). Human cells contain myriad excised linear intron RNAs with links to gene regulation and potential utility as biomarkers. PLoS genetics, 20(9), e1011416. . PMID: 39325823.

3.) Reed KB, Kim W, Lu H, Larue CT, Guo S, Brooks SM, Montez MR, Wagner JM, Zhang YJ, Alper HS (2024 Aug 27). Evolving dual-trait EPSP synthase variants using a synthetic yeast selection system. Proceedings of the National Academy of Sciences of the United States of America, 121(35), e2317027121. . PMID: 39159366.

4.) Arasappan D, Spears A, Shah S, Mayfield RD, Akula N, McMahon FJ, Jabbi M (2024 Aug 16). Brain transcriptomic signatures for mood disorders and suicide phenotypes: an anterior insula and subgenual ACC network postmortem study. bioRxiv : the preprint server for biology, (), . . PMID: 39185191.

5.) Aldrich JC, Vanderlinden LA, Jacobsen TL, Wood C, Saba LM, Britt SG (2024 Aug 7). Genome-Wide Association Study and transcriptome analysis reveals a complex gene network that regulates opsin gene expression and cell fate determination in Drosophila R7 photoreceptor cells. bioRxiv : the preprint server for biology, (), . . PMID: 39149333.

6.) Jost TA, Gardner AL, Morgan D, Brock A (2024 Jul 4). Deep learning identifies heterogeneous subpopulations in breast cancer cell lines. bioRxiv : the preprint server for biology, (), . . PMID: 39005432.

7.) Gardner AL, Jost TA, Brock A (2024 Jun 2). Computational identification of surface markers for isolating distinct subpopulations from heterogeneous cancer cell populations. bioRxiv : the preprint server for biology, (), . . PMID: 38854060.

8.) Presnell KV, Melhem O, Coleman SM, Morse NJ, Alper HS (2024 Jun). Design and synthesis of synthetic promoters for consistency of gene expression across growth phases and scale in S. cerevisiae. Synthetic and systems biotechnology, 9(2), 330-339. . PMID: 38549617.

9.) Wen X, Xu H, Woolley PR, Conway OM, Yao J, Matouschek A, Lambowitz AM, Paull TT (2024 May 8). Senataxin deficiency disrupts proteostasis through nucleolar ncRNA-driven protein aggregation The Journal of Cell Biology, 223(7), e202309036. . PMCID: 11080644.

10.) Reed KB, d'Oelsnitz S, Brooks SM, Wells J, Zhao M, Trivedi A, Eshraghi S, Alper HS (2024 Apr 19). Fluorescence-Based Screens for Engineering Enzymes Linked to Halogenated Tryptophan. ACS synthetic biology, 13(4), 1373-1381. doi: 10.1021/acssynbio.3c00616. PMID: 38533851.

11.) Reed KB, Brooks SM, Wells J, Blake KJ, Zhao M, Placido K, d'Oelsnitz S, Trivedi A, Gadhiyar S, Alper HS (2024 Apr 12). A modular and synthetic biosynthesis platform for de novo production of diverse halogenated tryptophan-derived molecules. Nature communications, 15(1), 3188. . PMID: 38609402.

12.) Panina SB, Schweer JV, Zhang Q, Raina G, Hardtke HA, Kim S, Yang W, Siegel D, Zhang YJ (2024 Apr 12). Targeting of REST with rationally-designed small molecule compounds exhibits synergetic therapeutic potential in human glioblastoma cells. BMC biology, 22(1), 83. . PMID: 38609948.

13.) Warden A, Mayfield RD, Gurol KC, Hutchens S, Liu C, Mukhopadhyay S (2024 Feb 7). Loss of SLC30A10 manganese transporter alters expression of neurotransmission genes and activates hypoxia-inducible factor signaling in mice. Metallomics : integrated biometal science, 16(2), . . PMID: 38285613.

14.) Faske TM, Agneray AC, Jahner JP, Osuna-Mascaró C, Sheta LM, Richardson BA, Leger EA, Parchman TL (2024 Feb 1). Environment predicts the maintenance of reproductive isolation in a mosaic hybrid zone of rubber rabbitbrush. Evolution; international journal of organic evolution, 78(2), 300-314. doi: 10.1093/evolut/qpad207. PMID: 37962379.

15.) Salem NA, Manzano L, Keist MW, Ponomareva O, Roberts AJ, Roberto M, Mayfield RD (2024 Jan). Cell-type brain-region specific changes in prefrontal cortex of a mouse model of alcohol dependence. Neurobiology of disease, 190(), 106361. . PMID: 37992784.

16.) Zuniga A, Han J, Miller-Crews I, Agee LA, Hofmann HA, Drew MR (2024 Jan 1). Extinction Training Suppresses Activity of Fear Memory Ensembles Across the Hippocampus and Alters Transcriptomes of Fear-Encoding Cells. bioRxiv : the preprint server for biology, (), . . PMID: 38260411.

17.) Engels SM, Kamat P, Pafilis GS, Li Y, Agrawal A, Haller DJ, Phillip JM, Contreras LM (2023 Dec 28). Particulate matter composition drives differential molecular and morphological responses in lung epithelial cells PNAS Nexus, 3(1), pgad415. . PMCID: 10754159.

18.) Woolley PR, Wen X, Conway OM, Ender NA, Lee JH, Paull TT (2023 Dec 7). Regulation of transcription patterns, poly-ADP-ribose, and RNA-DNA hybrids by the ATM protein kinase bioRxiv, (), 2023.12.06.570417. . PMCID: 10723464.

19.) Smith CH, Mejia-Trujillo R, Breton S, Pinto BJ, Kirkpatrick M, Havird JC (2023 Nov 3). Mitonuclear Sex Determination? Empirical Evidence from Bivalves. Molecular biology and evolution, 40(11), . . PMID: 37935058.

20.) Ma CH, Kumar D, Jayaram M, Ghosh SK, Iyer VR (2023 Oct). The selfish yeast plasmid exploits a SWI/SNF-type chromatin remodeling complex for hitchhiking on chromosomes and ensuring high-fidelity propagation. PLoS genetics, 19(10), e1010986. . PMID: 37812641.

21.) Bazzi SA, Maguire C, Mayfield RD, Melamed E (2023 Sep 22). Alcohol induces concentration-dependent transcriptomic changes in oligodendrocytes. bioRxiv : the preprint server for biology, (), . . PMID: 37790537.

22.) Roberson EC, Tran NK, Godambe AN, Mark H, Nguimtsop M, Rust T, Ung E, Barker LJ, Fitch RD, Wallingford JB (2023 Sep 20). Hedgehog signaling is required for endometrial remodeling and myometrial homeostasis in the cycling mouse uterus iScience, 26(10), 107993. . PMCID: 10551904.

23.) Deshpande RA, Marin-Gonzalez A, Barnes HK, Woolley PR, Ha T, Paull TT (2023 Sep 16). Genome-wide analysis of DNA-PK-bound MRN cleavage products supports a sequential model of DSB repair pathway choice Nature Communications, 14(), 5759. . PMCID: 10505227.

24.) Mondal I, Das O, Sun R, Gao J, Yu B, Diaz A, Behnan J, Dubey A, Meng Z, Eskandar E, Xu B, Lu RO, Ho WS (2023 Aug 1). PP2Ac Deficiency Enhances Tumor Immunogenicity by Activating STING-Type I Interferon Signaling in Glioblastoma. Cancer research, 83(15), 2527-2542. . PMID: 37219874.

25.) Ramachandran J, Chen W, Lex RK, Windsor KE, Lee H, Wang T, Zhou W, Ji H, Vokes SA (2023 Jul 17). The BAF chromatin complex component SMARCC1 does not mediate GLI transcriptional repression of Hedgehog target genes in limb buds. bioRxiv : the preprint server for biology, (), . . PMID: 36798239.

26.) Smith CH, Mejia-Trujillo R, Breton S, Pinto BJ, Kirkpatrick M, Havird JC (2023 Jul 7). Mitonuclear sex determination? Empirical evidence from bivalves. bioRxiv : the preprint server for biology, (), . . PMID: 37461691.

27.) Wright ML, Podnar J, Longoria KD, Nguyen TC, Lim S, Garcia S, Wylie D (2023 May 4). Comparison of commercial DNA extraction kits for whole metagenome sequencing of human oral, vaginal, and rectal microbiome samples. bioRxiv : the preprint server for biology, (), . . PMID: 36778319.

28.) Coleman SM, Cordova LT, Lad BC, Ali SA, Ramanan E, Collett JR, Alper HS (2023 Mar). Evolving tolerance of Yarrowia lipolytica to hydrothermal liquefaction aqueous phase waste. Applied microbiology and biotechnology, 107(5), 2011-2025. doi: 10.1007/s00253-023-12393-8. PMID: 36719433.

29.) Yuan SF, Nair PH, Borbon D, Coleman SM, Fan PH, Lin WL, Alper HS (2022 Nov). Metabolic engineering of E. coli for β-alanine production using a multi-biosensor enabled approach. Metabolic engineering, 74(), 24-35. doi: 10.1016/j.ymben.2022.08.012. PMID: 36067877.

30.) Presnell KV, Melhem O, Morse NJ, Alper HS (2022 Oct 21). Modular, Synthetic Boolean Logic Gates Enabled in Saccharomyces cerevisiae through T7 Polymerases/CRISPR dCas9 Designs. ACS synthetic biology, 11(10), 3414-3425. doi: 10.1021/acssynbio.2c00327. PMID: 36206523.

31.) Hillsley A, Santoso MS, Engels SM, Halwachs KN, Contreras LM, Rosales AM (2022 Jul 18). A strategy to quantify myofibroblast activation on a continuous spectrum. Scientific reports, 12(1), 12239. . PMID: 35851602.

32.) Lu H, Diaz DJ, Czarnecki NJ, Zhu C, Kim W, Shroff R, Acosta DJ, Alexander BR, Cole HO, Zhang Y, Lynd NA, Ellington AD, Alper HS (2022 Apr). Machine learning-aided engineering of hydrolases for PET depolymerization. Nature, 604(7907), 662-667. doi: 10.1038/s41586-022-04599-z. PMID: 35478237.

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Associations

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Metadata

Links

All the links listed resolve to this core profile

https://coremarketplace.org/?FacilityID=1209
https://coremarketplace.org/RRID:SCR_021713

Institution

Institution ROR ID: https://ror.org/00hj54h04

SciCrunch Data Imports (data maintained by https://scicrunch.org)

Keywords:

USEDit, ABRF, sequencing core, Sanger Sequencing service, Next Generation Sequencing service, library preparation, quality check service

Resource Type:

core facility, service resource, access service resource

Citation:

University of Texas at Austin Genomic Sequencing and Analysis Core Facility (RRID:SCR_021713)

Genomic Sequencing and Analysis Facility (Genomics / Genome Analysis and Technologies)

Facility LIMS Page

Primary Contact:

Facility RRID

Facility Details

Facility Policies

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Services offered:

Facility Equipment

(To see more facility information, click the in the upper right)

Publications

(To see more facility information, click the in the upper right)

Associations

(To see more facility information, click the in the upper right)

Metadata

SciCrunch Data Imports (data maintained by https://scicrunch.org)

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Genomic Sequencing and Analysis Facility

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