The CoreMarketplace: Vanderbilt Genome Editing Resource

The Vanderbilt Genome Editing Resource (VGER) provides services, consultation, and collaborations to enable the generation, storage and regeneration of genetically altered mice.

We have many years of experience in generating novel transgenic mouse models and are happy to discuss your project with you.

Facility Policies

Services are offerred outside of Vanderbilt University

Consulting is not offerred outside of Vanderbilt University

(To see more facility information, click the in the upper right)

Services offered:

Animal Husbandry

Assisted Reproductive Technologies (Rodent IVF, ICSI)

CRISPR/Cas Project Design

Embryo Cryopreservation & Recovery Services

Genotyping

Provide Germfree Mice

Rederivation

Repository

Transgenics

Facility Equipment

No additional equipment has been listed

(To see more facility information, click the in the upper right)

Publications

Publications associated with this facility (Click To View):

1.) Trinh LT, Finnel RR, Osipovich AB, Musselman JR, Sampson LL, Wright CV, Magnuson MA (2025 Jan 16). Positive autoregulation of Sox17 is necessary for gallbladder and extrahepatic bile duct formation Development (Cambridge, England), 152(2), dev203033. . PMCID: 11829758.

2.) Gu G, Brown M, Agan V, Nevills S, Hu R, Simmons A, Xu Y, Yang Y, Yagan M, Najam S, Dadi P, Sampson L, Magnuson M, Jacobson D, Lau K, Hodges E (2024 Mar 7). Endocrine islet β-cell subtypes with differential function are derived from biochemically distinct embryonic endocrine islet progenitors that are regulated by maternal nutrients Research Square, (), rs.3.rs-3946483. . PMCID: 10942487.

3.) Nakhe AY, Dadi PK, Kim J, Dickerson MT, Behera S, Dobson JR, Shrestha S, Cartailler JP, Sampson L, Magnuson MA, Jacobson DA (2024 Feb 27). The MODY-associated KCNK16 L114P mutation increases islet glucagon secretion and limits insulin secretion resulting in transient neonatal diabetes and glucose dyshomeostasis in adults. bioRxiv : the preprint server for biology, (), . . PMID: 37546831.

4.) Keller MP, Hawes EM, Schueler KL, Stapleton DS, Mitok KA, Simonett SP, Oeser JK, Sampson LL, Attie AD, Magnuson MA, O'Brien RM (2023 Nov 1). An Enhancer Within Abcb11 Regulates G6pc2 in C57BL/6 Mouse Pancreatic Islets. Diabetes, 72(11), 1621-1628. . PMID: 37552875.

5.) Winn NC, Patel VS, Blair JA, Rodriguez A, Garcia JN, Yang TS, Hasty AH (2023 Oct 1). Deletion of complement factor 5 amplifies glucose intolerance in obese male but not female mice. American journal of physiology. Endocrinology and metabolism, 325(4), E325-E335. . PMID: 37610411.

6.) Cencer CS, Silverman JB, Meenderink LM, Krystofiak ES, Millis BA, Tyska MJ (2023 Mar 9). Adhesion-based capture stabilizes nascent microvilli at epithelial cell junctions. bioRxiv : the preprint server for biology, (), . . PMID: 36945471.

7.) Burman A, Momoh M, Sampson L, Skelton J, Roland JT, Ramos C, Krystofiak E, Acra S, Goldenring JR, Kaji I (2023). Modeling of a Novel Patient-Based MYO5B Point Mutation Reveals Insights Into MVID Pathogenesis. Cellular and molecular gastroenterology and hepatology, 15(4), 1022-1026. . PMID: 36592862.

8.) Wu HJ, Mortlock DP, Kuchtey RW, Kuchtey J (2021 Aug 2). Altered Ocular Fibrillin Microfibril Composition in Mice With a Glaucoma-Causing Mutation of Adamts10. Investigative ophthalmology & visual science, 62(10), 26. . PMID: 34424262.

9.) Shumate KM, Tas ST, Kavalali ET, Emeson RB (2021 Jul). RNA editing-mediated regulation of calcium-dependent activator protein for secretion (CAPS1) localization and its impact on synaptic transmission. Journal of neurochemistry, 158(2), 182-196. doi: 10.1111/jnc.15372. PMID: 33894004.

(To see more facility information, click the in the upper right)

Associations

Cancer Center

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Metadata

Links

All the links listed resolve to this core profile

https://coremarketplace.org/?FacilityID=773
https://coremarketplace.org/RRID:SCR_018826

Institution

Institution ROR ID: https://ror.org/02vm5rt34

SciCrunch Data Imports (data maintained by https://scicrunch.org)

Keywords:

USEDit, genetically altered mice, CRISPR-Cas9 mouse editing, Pronuclear Microinjection of DNAs, Embryo Cryopreservation, Genome Editing Design, sperm Cryopreservation, In vitro Fertilization, , ABRF, ABRF

Resource Type:

core facility, service resource, access service resource

Citation:

Vanderbilt University Genome Editing Resource Core Facility (RRID:SCR_018826)

Vanderbilt Genome Editing Resource (Genomics / Genome Analysis and Technologies)

Quicklinks:

Facility LIMS Page

Primary Contact:

Facility RRID

Additional Citation Identifiers

Facility Details

Facility Policies

(To see more facility information, click the in the upper right)

Services offered:

Facility Equipment

(To see more facility information, click the in the upper right)

Publications

(To see more facility information, click the in the upper right)

Associations

Cancer Center

(To see more facility information, click the in the upper right)

Metadata

SciCrunch Data Imports (data maintained by https://scicrunch.org)

Facility Profile QR Code (links to this profile)

(To see more facility information, click the in the upper right)

Contact Jennifer Skelton

Contact The CoreMarketplace

Vanderbilt Genome Editing Resource

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