primary_duns:
066811191
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All Facilities >> University of Vermont >> UVM VBRN Proteomics Facility (Proteomics)
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Ying Wai Lam
Last Updated: 01/15/2025
VBRN Proteomics Facility is supported by INBRE funding (P20GM103449) and is located in the Marsh Life Science Building at the University of Vermont. It occupies 1,408 ft2 of lab, data processing unit, office, and consultation space. The Proteomics Facility enables investigators to use an array of state-of-the-art mass spectrometry-based techniques for proteomics experiments, ranging from routine protein identification, post-translational modification characterization and finding protein interacting partners, to large-scale quantitative proteomics analyses using stable isotopes (dimethyl labeling, SILAC, TMT). Since its inception in 2006, the facility has analyzed over 20,000 samples and supported close to 180 publications (https://vbrn.org/proteomics-publications/). The facility personnel train investigators in experimental design and proteomics methods, while assisting with data interpretation, manuscript preparation, and grant submission. Our user base includes investigators from UVM and from institutions in 15 states.
A summary of the facility’s impact on the development of the network can be found at https://vbrn.org/proteomics-impact/.
Core Facility website: https://vbrn.org/proteomics/
is_active:
Yesbudget_end:
05/31/2025date_added:
06/01/2024agency_code:
NIHfiscal_year:
2024project_num:
5P20GM103449-23award_amount:
$425,364.00budget_start:
06/01/2024org_name:
UNIVERSITY OF VERMONT & ST AGRIC COLLEGEorg_state:
VTorg_country:
UNITED STATESorg_zipcode:
054051704primary_duns:
066811191abstract_text:
PROTEOMICS CORE - Summary The mission of the Vermont Genetics Network (VGN) Proteomics Core is to provide high-quality, timely, and affordable service to network clients for state-or-the-art proteomic analyses. Previously, Vermonters had to use mass spectrometry facilities outside of the state, often at high prices and with low priority service. The VGN Core has changed that. In addition to supporting faculty research, the Core also supports the outreach, education, and training of students in the development of contemporary proteomics skills that will prepare them for graduate-level research training or entry into the biomedical workforce. Since 2006, the Core has been providing mass spectrometry expertise and services to the research community. The staff consults with investigators during experimental design, assists with sample preparation, and provides data (in collaboration with Bioinformatics Core staff) so that network investigators can collect and use the data in publications and be competitive for extramural funding. The Core also provides unique educational outreach opportunities to students through the integration of the proteomics course module into classes and use of proteomics in their VGN-funded research. The component is innovative in that students have hands-on experience with the state-of-the-art proteomics technologies and learn to interpret proteomics data derived from their samples analyzed by the Core. The major aims of the Core are: Provide high quality and timely proteomics services to network faculty and students; establish new proteomics methodologies for the benefit of the network and other clients; sustain the Core by refining its operating procedures; and work with the Administrative Core to assess Core operations.project_title:
Proteomics Corecontact_pi_name:
LAM, YING WAItotal_cost:
$425,364.00is_active:
Nobudget_end:
05/31/2024date_added:
06/03/2023agency_code:
NIHfiscal_year:
2023project_num:
5P20GM103449-22award_amount:
$425,370.00budget_start:
06/01/2023org_name:
UNIVERSITY OF VERMONT & ST AGRIC COLLEGEorg_state:
VTorg_country:
UNITED STATESorg_zipcode:
054051704primary_duns:
066811191abstract_text:
PROTEOMICS CORE - Summary The mission of the Vermont Genetics Network (VGN) Proteomics Core is to provide high-quality, timely, and affordable service to network clients for state-or-the-art proteomic analyses. Previously, Vermonters had to use mass spectrometry facilities outside of the state, often at high prices and with low priority service. The VGN Core has changed that. In addition to supporting faculty research, the Core also supports the outreach, education, and training of students in the development of contemporary proteomics skills that will prepare them for graduate-level research training or entry into the biomedical workforce. Since 2006, the Core has been providing mass spectrometry expertise and services to the research community. The staff consults with investigators during experimental design, assists with sample preparation, and provides data (in collaboration with Bioinformatics Core staff) so that network investigators can collect and use the data in publications and be competitive for extramural funding. The Core also provides unique educational outreach opportunities to students through the integration of the proteomics course module into classes and use of proteomics in their VGN-funded research. The component is innovative in that students have hands-on experience with the state-of-the-art proteomics technologies and learn to interpret proteomics data derived from their samples analyzed by the Core. The major aims of the Core are: Provide high quality and timely proteomics services to network faculty and students; establish new proteomics methodologies for the benefit of the network and other clients; sustain the Core by refining its operating procedures; and work with the Administrative Core to assess Core operations.project_title:
Proteomics Corecontact_pi_name:
LAM, YING WAItotal_cost:
$425,370.00Services are offerred outside of University of Vermont
Consulting is offerred outside of University of Vermont
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Thermo Fisher LTQ Orbitrap Discovery Mass Spectrometer
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Thermo LTQ Orbitrap XL ETD Hybrid Ion Trap-Orbitrap Mass Spectrometer
Thermo Scientific LTQ Orbitrap XL ETD Hybrid Ion Trap-Orbitrap Mass Spectrometer can be used to identify, characterize and quantify proteins and peptides using. This instrument is a comprehensive solution for a range of proteomics applications including complex PTM analysis; intelligent sequencing of peptides; top-down and middle-down analysis; label-free quantitation; or quantitation using stable isotope labeling methods such as TMT and iTRAQ. [Product Link]
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Thermo LTQ XL Linear Ion Trap Mass Spectrometer
Ion trap mass spectrometer with Agilent 1100 HPLC system is used for a variety of studies including metabolite identification, stability testing, degradation products, and high-abundance quantitation. [Product Link]
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Thermo Q Exactive Plus Hybrid Quadrupole-Orbitrap Mass Spectrometer
Q Exactive Plus Hybrid Quadrupole-Orbitrap Mass Spectrometer has increased performance and new options that enhance applications from confident DMPK qual/quan screening studies to characterization of intact monoclonal antibodies. [Product Link]
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Thermo Scientific Orbitrap Fusion Tribrid Mass Spectrometer
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Leap Technologies HDX workflow station HDx-3 PAL
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Institution ROR ID: https://ror.org/0155zta11Keywords:
USEDit, mass spectrometry, proteomics technology, protein, biomedical sample, protein analysis, peptide, measurement, experimental design, ABRF
Resource Type:
core facility, service resource, access service resource
Citation:
Vermont University Proteomics Core Facility (RRID:SCR_018667)
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Facility Details
About This Facility
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