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All Facilities >> University of New England >> UNE-Rodent Behavior Core (Behavioral Research)
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11 Hills Beach Road
Biddeford, ME 04005
United States207-602-2773
https://une.edu/research/cobre/behavioralcite this facility
Denise Giuvelis
Last Updated: 05/02/2024
The Behavior Core provides a comprehensive approach to the research needs of the Center for Pain Research investigators, UNE researchers, and the external research community using the highest level of expertise, training, and instrumentation. The core provides in-house validation of cutting-edge models of pain and relevant co-morbidities to advance the pain field and early-stage drug discovery.
Services provided include (but are not limited to) the following:
- General Behavioral Phenotyping: Observational Screens, Motor Function
- Pain/Sensory Testing: Thermal, Mechanical, Chemical
- Additional Neurobehavioral Tests: Psychiatric, Addiction, Learning and Memory
- Surgical Models: Neuropathic pain, Post-operative pain
- Miscellaneous Systems: GI Transit, DXA/x-ray scans, and AI video analysis
- Necropsy Services: Perfusions and Post-mortem tissue collection
Other Services:
- Consultation in choosing behavioral test and statistical tests for assessing results
- Training in rodent handling, instrumentation, and behavior or surgical techniques
- Staff expertise includes surgical methods for producing pain models; dosing of drugs/anesthetics including central, systemic and localized administration; and tissue extractions
Services are offerred outside of University of New England
Consulting is offerred outside of University of New England
The Behavior Core is fully equipped for sterile rodent surgeries including SomnoFlo isoflurane vaporizers, a Leica operating microscope, heating pads, surgical instruments and instrument sterilizer in our facility.
In addition to surgical equipment, the core provides numerous instrumentation for behavioral assessments of multiple pain components, including the affective dimensions of pain and pain-suppressed behaviors as well as AI video analysis in an open-field type chamber.
Testing options for thermal & tactile sensitivities in mice and rats include: Thermal - hot water baths, hot/cold plate, and two Plantar Hargreaves apparatuses. Tactile - differential weight bearing assays, and either electronic or manual von Frey filaments with appropriate plastic chambers. We also have a thermal place preference test and COY conflict avoidance test.
Anxiety/Depression testing equipment for mice and rats include: an elevated plus-maze, tail-suspension, and forced swim chambers.
Coordination and activity tests to determine pain-suppressed behaviors: IITC Life Science Rotorod, running wheels, a Coulbourn TRU SCAN open field monitoring system, and a DigiGait Imaging System for treadmill gait analysis.
Motivational state testing equipment for mice and rats include: custom conditioned place preference/aversion chambers, operant chambers, and tub for Morris water maze experiments.
For learning and memory experiments, a Noldus-Ethovision Video Tracking equipment and software allows users to assess animal performance in a number of mazes as well as the novel object recognition test.
In addition to behavioral tests, we offer a wide expertise in a variety of related fields: optogenetics (TeleOpto system), blood collection for PK studies, colony management (breeding strategies, animal identification and tail snips) and necropsy services (perfusions and post-mortem tissue collection).
Please visit our website for a full list of our capabilities.
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https://coremarketplace.org/?FacilityID=758Institution
Institution ROR ID: https://ror.org/02n2ava60Keywords:
Technical, expertise, training, instrument, assess, behavior, function, nervous, system, acute, chronic, pain, mechanism, phenotypin, motor, learning, memory, cardiovascular, neurobehavioral, respiration, animal, training, genotyping, allele, gene, transgenic, mouse, line, PCR, primer, design, service, core, ABRF
Resource Type:
access service resource, core facility, service resource
Citation:
New England University Behavioral and Genotyping Core Facility (RRID:SCR_017883)
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