The LC/MS Proteomics Core Facility‘s (PCF) mission is to provide well-maintained, state-of-the-art instrumentation and fundamental proteomics expertise to the Brown University and Rhode Island scientific communities. We aim to be a focal point of intellectual activity in proteomics by enabling nationally recognized proteomics research within Rhode Island. We welcome inquiries from scientists and teachers seeking information regarding how we may assist them in furthering their research and educational goals. The facility‘s function is catalyzed by its Administrative Directors, Faculty advisor, responsible Facility Director, and a knowledgeable advisory committee. Together their research interests are based on the pursuit and implementation of proteomics approaches to biological inquiry.

As an NSF EPSCoR-funded laboratory, the Proteomics Facility has a broadly inclusive philosophy to ensure rapid and equal access to the facility‘s services for the entire Rhode Island research community. In addition to the acquisition of new instrumentation, the Proteomics Core Facility will undertake research in emerging proteomic techniques to maintain a productive and professional level of service. The PCF has a strong commitment to be at the leading edge of current and developing technologies and provides consultative services to users.

The Genomics Core Facility, located at 70 Ship Street, Room 109, provides state-of-the-art genomics and proteomics equipment and services to researchers at Brown University, the entire Rhode Island research community and external customers.

The facility offers DNA/RNA shearing, sample QC, Affymetrix microarray, qPCR services and provides assistance with experimental design, trouble shooting, and data analysis. Please see our menu for detailed information on the services offered, instruments available and current rates.

The core is available to students, staff and faculty at Brown as well as researchers from RI-EPSCoR institutions. Training is provided for new users. We welcome investigators to contact us regarding our services.

The purpose of this facility is to provide technical assistance to Brown researchers by performing flow cytometry-based analysis and sorting. The facility has a 4-laser, 19-parameter BD FACSAria III for flow and sorting applications.

The Structural Biology Core Facility at Brown University provides state-of-the art equipment for researchers at Brown University and the surrounding area. Our instruments can be used for structural modeling in crystals and in solution, using X-ray diffraction and scattering, as well as magnetic resonance.

The Leduc Bioimaging Facility, open to all investigators, provides equipment and training dedicated to high-resolution imaging in the life sciences. The facility includes a Transmission Electron Microscope, a Scanning Electron Microscope, two Fluorescence Microscopes, a Fluorescence Stereomicroscope, three Confocal Laser Scanning Microscopes, a Multiphoton Microscope, and software for image analysis. The facility also maintains equipment for sample preparation, including a critical point dryer, sputter coater, and microtomes for ultrathin sectioning.