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All Facilities >> Rhode Island Hospital >> COBRE for Skeletal Health and Repair - Molecular Biology Core
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Rhode Island Hospital
1 Hoppin St.
Coro West, Suite 402A
Providence, RI 02903
United States of Americahttp://www.orthoinstitute.org/research/osteoporosisQian Chen, Ph.D.
Last Updated: 03/02/2012
The COBRE for Skeletal Health and Repair in the Rhode Island Hospital enables clinicians and basic scientists, engineers and biologists to work side-by-side on multidisciplinary research, helping us to better understand cartilage and joint health mechanisms and develop strategies for the prevention and treatment of skeletal joint diseases.
Specific Aims:
-Provide sophisticated, state-of-the-art instrumentation in microscopic imaging and molecular analysis to different projects in the COBRE.
-Provide technical support and expert consultation in tissue, cell, and molecular, analysis to multidisciplinary users including biologists, clinicians and engineers.
-Provide training of cutting edge techniques in molecular and morphological analysis to investigators for achieving specific research objectives.
-Facilitate collaborations among different laboratories and disciplines through utilizing common equipment and analyzing techniques.
Services are offerred outside of Rhode Island Hospital
A list of the major equipment available in the Core is listed as follows:
-Nikon 90i Upright Research Microscope (fully automatic stage with digital deconvolution)
-Nikon Eclipse TS-100F Inverted Microscope with Phase Contrast/FITC/RFP
-Nikon Y-THR-L Tri-headed Teaching Microscope
-Leica KL 1500 Dissection Microscope with Polaroid Camera
-GloMax 20/20 Luminometer System + Printer
-VisEn FMT Fluorescence In Vivo Imaging System
-Luminex 200 System
-Scanco three-dimensional (3-D) microcomputed tomography (µCT)-40
-Faxitron X-Ray Machine
-Li-COR Odyssey Infrared Imager
-UVP Biochemi System (Bioimaging System with Epichemi Darkroom)
-Thermo Shandon Finesse Automatic Microtome and Heater Control Thermostat
-Leica CM1800 Cryostat
-Nanodrop ND100
-Thermo Biogate Spetrophotometer
-Qiagen QIAxcel
-Qiagen QIAgility
-Bio-Rad CFX96 Real-time System
-DNA Engine Opticon 2
-Verti 96 Well Thermal Cycler
-Bio-Rad C-1000 Thermal Cycler
-Bio-Rad S-1000 Thermal Cycler
-Labnet Multigene Thermal Cycler
-Labnet HERMLE 2400 Centrifuge
-Isotemp Vacuum Oven Model 280A
-Isotemp Hybridization Oven with Rotisserie Motor
-Sorvall Legend X1R Centrifuge with Rotors
-Sorvall Discovery 100SE Ultraspeed Centrifuge with Rotors
-Fisher Bench-Top Centrifuge CL2
-Eppendorf Microcentrifuge 5424 (X3)
-Orbital Microplate Shaker
-VWR 12L Shaking Water Bath
-Fisher Scientific PowerGen125 Homogenizer Package
-BioRad Sub-Cell Electrophoresis Systems
-Trans-blot Electrophoretic Transfer Cell Complete Unit
-Packard Tri-Carb 2900TR Liquid Scintillation Analyzer
-AGFA CP1000 Film Developer
-Various 4 Degrees Refrigerator and Minus 20 and Minus 80 Freezers
-Nuaire CO2 Water-Jacketed Incubators
-Nuaire Class II Type A/B3 Biological Safety Cabinets
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