Search the CoreMarketplace
Searching
All Facilities >> University of Kentucky >> Center for Molecular Medicine Organic Synthesis Core
Facility Details
About This Facility
Services and Equipment
Publications
Awards & Associations
Metadata
University of Kentucky
Lexington, KY 40536
United States of Americahttps://cobre.med.uky.edu/im-organic-synthesis-coreTrevor Creamer
Last Updated: 01/25/2018
The Organic Synthesis Core provides biological investigators with access to “small†organic compounds that allow investigators to probe important biological questions relevant to the molecular basis of human medicine.
The core maintains an open-door policy for consultation. In a collaborative process, the Core designs specific small molecules and tailors these small molecules to include suitable functional groups for linkage to proteins, peptide-nucleic-acid (PNA) mimics or to suitable markers for the detection and monitoring of a particular drug or natural product. Tailoring includes the incorporation of fluorescent tags, photoactive groups, non-radiogenic labels (e.g., deuterium) or radiolabels, as needed. The laboratory maintains equipment needed for organic synthesis and utilizes infrared, ultraviolet, mass spectrometry and nuclear magnetic resonance instrumentation to characterize adducts and to establish their purity. The Core also assists investigators with the characterization and purification of compounds acquired from other sources. The Core does not synthesize compounds available from commercial sources.
Training opportunities are available for graduate students, technicians and postdoctoral fellows from other research groups who wish to learn a particular technique and subsequently import it into their research group. The core provides access to equipment: melting point devices, low-pressure distillation equipment, photochemical apparatus, specialized glassware and chromatographic systems not generally available in biochemical laboratories and provides access to this equipment to any investigators who need it.
Services are offerred outside of University of Kentucky
Consulting is not offerred outside of University of Kentucky
No equipment has been listed
No publications have been associated with this facility
Keywords:
This facility has not been assigned an RRID
Resource Type:
This facility has not been assigned an RRID
Citation:
This facility has not been assigned an RRID
Your Email:
Your Phone (optional):
Message: