The IGC Mass Spectrometry Facility at the University of Edinburgh offers expert-led proteomics, metabolomics, and lipidomics services to academic and industrial researchers. With over 16,000 citations and 180+ publications, we bring world-class analytical capability and biological expertise to your research questions.
We specialise in working with precious and low-input samples — including single-cell proteomics, deep visual proteomics from FFPE tissue, and integrated multiomics from a single sample. Every project is supported from experimental design through to full bioinformatic analysis and biological interpretation.
Our Three Pillars:
Proteomics: from bulk expression to single-cell and spatial resolution
Metabolomics: precise identification and isotope tracing of metabolic pathways
Lipidomics: high-accuracy profiling of cellular lipid landscapes and signalling
Our Speciality: Spatial, Single-Cell and Integrated Multiomics: proteins, metabolites and lipids from the same precious sample.
Facility Policies
Services are offerred outside of
Consulting is offerred outside of this institution
The timsTOF SCP (single-cell proteomics) is mass spectrometer from Bruker. Ultra-high sensitivity instrument for quantitative single cell biology research with unbiased, deep single-cell 4D-Proteomics, immunopeptidomics, epiproteomics and PTM analysis. It features an additional separation in the tims cell where ions get separated according to their ion mobility, leading to collision cross-section values.Allows the analysis of hundreds of samples with minimal sample load (<200 ng) at sequencing speeds exceeding 100 Hz. [Product Link]
Automatic Magnetic Bead Cell Isolation System. Benchtop instrument for the purification and extraction of DNA, RNA, proteins, and cells in laboratory settings. It uses magnetic particle technology to handle medium to high throughput processing of 24 or 96 samples per run, providing a more efficient and consistent alternative to manual methods. [Product Link]
Thermo Q Exactive Plus Hybrid Quadrupole-Orbitrap Mass Spectrometer
Q Exactive Plus Hybrid Quadrupole-Orbitrap Mass Spectrometer has increased performance and new options that enhance applications from confident DMPK qual/quan screening studies to characterization of intact monoclonal antibodies. [Product Link]
Thermo Scientific Orbitrap Astral Zoom Mass Spectrometer
Spectrometer includes: Fast Ion Filter, Bent Trap for Pre-Accumulation, High-speed Quadrupole, Faster Stepped Collision Energy, Enhanced Dynamic Range mode, TMT HR mode, low input mode, Enhanced Spectral Processing, support for Hybrid DIA experiments, and expanded BioPharma option including Thermo Scientific™ Astral™ analyzer support for top-down and middle-down measurements. Used to accelerate deep proteomics and single-cell analysis. Combines fast scan rates with high-resolution, accurate-mass (HRAM) measurements to detect more proteins, analyze thousands of cells daily, and improve precision oncology or clinical biomarker discovery. [Product Link]
Thermo Scientific Orbitrap Fusion Lumos Tribrid Mass Spectrometer
Spectrometer performs analysis including low level PTM analysis, multiplexed relative quantitation using isobaric tags, intact protein characterization, and MSn analysis of small molecules. System incorporates the brightest ion source, segmented quadrupole mass filter with improved selectivity and ion transmission, Advanced Vacuum Technology, and ETD HD. [Product Link]
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