Training and support to research with human embryonic and induced pluripotent stem cells (iPSC). Offers opportunity to dissect early human development, generate models of disease, and develop cellular or drug therapeutics.

We are a flow cytometry core facility located at the Faculty of Medicine providing cutting edge instrumentation and expertise to researchers in Ottawa and around the world. We specialize in single-particle analysis of viruses and extracellular vesicles.

Provides unique imaging (JEOL JEM-1400plus) and tissue processing solutions for your research, in partnership with CHEO’s Electron Microscope Laboratory. Provides training for use of the instrument, and training for sample preparation/processing.

The Preclinical Imaging Core (PCIC) Facility offers internal and external clients end-to-end experimental solutions to carry out animal studies requiring in vivo imaging, including consultations, research plan design, protocol development, data collection, analysis, and reporting. PCIC offers modalities like MRI and ultrasound enabling translational research.

The Cell Biology and Image Acquisition (CBIA) Core Facility provides state-of-the-art advanced microscopes, image analysis tools, and technical support to facilitate your microscopy research. We offer consultations to determine the most appropriate microscope for your specific needs and the proper design of your experimental set-up. In addition, we provide comprehensive training and follow-up sessions for all first-time users, ensuring optimal use of the imaging systems. The CBIA Core Facility is located within Roger Guindon Hall at the University of Ottawa. Facility resources are available to all uOttawa principal and adjunct investigators, with pay-per-access fee structure geared towards outside academics, government, NGOs, and industry.

The CBIA core is open from Monday to Friday: 8:00AM to 6:00 PM with after hours access for heavy users. The staff is available during working hours to respond to any issues that may arise while using one of our microscopes or any image analysis issue.

We are a full-service histology laboratory available to faculty, researchers, clinicians and students. The primary mission of the HCF is to provide efficient, high quality and cost-effective histological services for both animal and human tissue. HCF services include paraffin processing and embedding, paraffin and frozen sectioning as well as routine and special histological staining.

The LPHCF laboratory is equipped with:
A Leica Bond III Immunostainer to provide automated immunohistochemistry, in-situ hybridization and immunofluorescence staining
Automated tissue processors for paraffin processing
Automated microtomes for paraffin sectioning
Automated stainer that can be programmed to provide a wide variety of routine and special stains
Cryostats for sectioning frozen tissue
Tissue Microarray machine - Coming Soon!
The LPHCF can also perform manual chromogenic or fluorescent staining (single or multi-color labelling) on frozen and paraffin sections. We also provide full service slide scanning using the newly acquired Axio Scan.Z1 for Brightfield or Fluorescent stained slides at either 20X or 40X magnification.

Experienced personnel in the LPHCF are available for consultation on project/protocol design, technical assistance and training on facility instruments. The Infinity software system is used for all of our histological services and instrument training.

A facility assisting researchers in mammalian genome editing and molecular biology, including CRISPR genetic libraries and screens as well as custom viral vector/particle production. Projects are customized to the researchers needs, from full-service cell line creation to design and cloning.

The Animal Behaviour and Physiology Core facility was established in 2009 and provides a state-of-the-art facility equipped to serve as a time-efficient and cost-effective service for researchers in need of mouse and rat behavioural analyses.

We are a Core Facility of the University of Ottawa and the Ottawa Hospital Research Institute. We provide advice on bioinformatics research design, conduct bioinformatics analysis, and provide support for grant proposals that involve bioinformatics (including conducting pilot studies, support/collaboration letters and methodological text)

Our areas of expertise include:

Analysis of high-throughput sequencing data; single cell (Chromium 10x), RNA-seq (including small RNA), ChIP-seq, ATAC-seq, Hi-C.
Large scale analysis integrating multiple data types
We have experience with many other types of bioinformatics, and/or can refer you to other local exports, depending on your needs. We can also help to arrange for the analysis of your biological samples with local core facilities such as StemCore, the Proteomics Resource Center, or the OHRI Mass Spectrometry Core Facility.

We provide yearly training courses in RNA-seq analysis and Bioinformatics analysis using R as well as individual training and analysis support on request. We maintain a document containing a summary of our sequencing experiment recommendations for client use.

Please contact us to discuss your project and how we might help you: gpalidwor@ohri.ca.

Please note that our hourly rates will be increasing as of June 1, 2022:

$85/hr: OHRI or uOttawa clients (from $80/hr)
$120/hr: external academic clients (from $110/hr)
$140/hr: industry clients (from $110/hr)

All rates are in Canadian Dollars.