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All Facilities >> Lunenfeld-Tanenbaum Research Institute >> Network Biology Collaborative Centre High-Throughput Screening (High Throughput Screening)
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Lunenfeld-Tanenbaum Research Institute
600 University Avenue
Mount Sinai Hospital, Sinai Health
Toronto, ON M5G 1X5
United States of Americahttps://nbcc.lunenfeld.ca/facilities/high-throughput-screeningcite this facility
Jenny Wang
Last Updated: 06/03/2024
The high-throughput screening facility of the Network Biology Collaborative Centre (NBCC) provides cutting-edge instrumentation and in-depth expertise for the automation of laboratory processes. Directed by Dr. Jeff Wrana, the facility has 2 automated screening platforms and accessory equipment to enable flexible and scalable in vitro and in vivo assays (including organoids).
Our full-service offerings include access to chemical and genome-wide siRNA libraries, assay development and implementation, and data analysis.
Applications include:
drug discovery and lead validation
ELISA-based assays for immune surveillance
protein biomarker discovery using OLINK proteomics technology
multiplexed barcode screening assays
Services are offerred outside of Lunenfeld-Tanenbaum Research Institute
Consulting is offerred outside of Lunenfeld-Tanenbaum Research Institute
BioMek NXp NXp
Beckman Coulter Biomek NXp Robotic Liquid Handler is designed to handle every aspect of liquid handling, pipetting, dilution, dispensing and integration in to one compact unit that will let you add laboratory automation where you need it. This efficient robotic liquid handler is set with a Span-8 pipette model, 4 fixed tip heads and 4 disposables, with rotating gripper and 8 channel liquid level sensing for an efficient and hands-free workflow. This automated workstation has up to 12 deck positions, automated labware positioners, and labware stacking for on deck storage. The open-ended flexibility of this robotic handler helps keep your lab agile and adaptable to your needs. The Beckman Coulter Biomek NXp Automated Workstation has a dispensing volume of between 0.5 ?L - 5,000 ?L and supports labware from tubes to 1,536-well microplates with accurate intra-well pipetting. The Biomek NXP can integrate with third party devices, and is configurable to meet specific applications needs. This automated workstation is computer controlled through the Biomek software, a robust suite that compliments this efficient instrument with methods and capabilities for genomic, drug discovery & basic research workflows. The Biomek software guides users through set up and protocols, quickly and easily through an icon based interface, with data tracking and LIMS connectivity. [Product Link]
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EnVision® 2105 Multimode Plate Reader
The EnVision® 2105 is a multimode microplate reader that provides speed, ultra-high throughput, and maximum sensitivity across all detection technologies.The EnVision 2105 model provides higher sensitivity for time-resolved fluorescence (TRF) applications, and the Enhanced Security software option includes tools to facilitate 21 CFR Part 11 compliance for integration into regulated environments (GxP). [Product Link]
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https://coremarketplace.org/?FacilityID=2809Institution
Institution ROR ID: https://ror.org/01s5axj25Keywords:
ABRF, siRNA libraries, screening platforms and accessory equipment, ELISA, in vitro and in vivo assays, organoids, multiplexed barcode screening assays,
Resource Type:
access service resource, service resource, core facility
Citation:
Lunenfeld-Tanenbaum Research Institute Network Biology Collaborative Centre High-Throughput Screening Core Facility (RRID:SCR_025390)
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