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Arpege (Pharmacology (Analytical, Research))

Institut de Génomique Fonctionnelle

c/o IGF, 141 rue de la Cardonille




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Primary Contact:

Damien Maurel

Last Updated: 06/26/2023

Facility RRID


Facility Details

ARPEGE is specialized in the functional and structural analysis of protein complexes. This facility offers the possibility to characterize all types of molecular interactions: ligand-target binding, protein-protein interactions, signal transduction, and signalling complexes. The facility staff members are skilled specialists in luminescence-based techniques and in receptor biology.

Application portfolio:

- Analysis of cell signalling, by measuring signal transduction,
- Ligand-target binding (pharmacological analysis, affinity, selectivity),
- Protein-protein interactions (oligomerization, effectors...),
- Activation of signalling pathways (G proteins, GRK, arrestins & internalization),
- Intracellular production of second messengers (cAMP, IP1, Ca2+),
- Phosphorylation of signalling proteins (ERK, AKT...),
- Measurement of global cell functions and of different cell parameters (proliferation, migration, invasion...).

Facility Policies

Services are offerred outside of Institut de Génomique Fonctionnelle

Consulting is offerred outside of Institut de Génomique Fonctionnelle