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All Facilities >> Stowers Institute for Medical Research >> SIMR Genome Engineering (Genomics / Genome Analysis and Technologies)
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1000 East 50th Street
Kansas City, MO 64110
United Stateshttps://www.stowers.org/technology-centers/genome-engineeringcite this facility
Kym Delventhal
Our core supports genome engineering using CRISPR technology. We provide services to generate knockouts, insertions, deletions, and point mutations in various organisms. Services for genome engineering include guideRNA design, homology-directed repair template design, production of modified mammalian cell lines, preparation of reagents for delivery to embryos, and mutation detection by targeted deep sequencing.
Pooled screening is also coordinated and supported by our team. We acquire, prepare, and validate pooled libraries as an Institute resource. In coordination of our pooled screen workflow, we work with other teams to track the progress of these projects. Once resulting cell populations from the screen are delivered, our team does genomic DNA purification, target amplification, and preparation for NGS.
We now offer a TAIL-PCR service to identify the location of random integration events. We have successfully identified locations in killifish, fly, zebrafish, and sea anemone.
Lastly, our team is responsible for maintaining and distributing the clone and vector collections for the Institute.
Services are not offerred outside of
Consulting is offerred outside of Stowers Institute for Medical Research
Last Updated: 05/19/2025
No additional equipment has been listed
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https://coremarketplace.org/?FacilityID=1216Institution
Institution ROR ID: https://ror.org/04bgfm609Keywords:
USEDit, ABRF, genome engineering, CRISPR technology, pooled libraries, genomic DNA purification, target amplification, and preparation for NGS
Resource Type:
access service resource, service resource, core facility
Citation:
Stowers Institute for Medical Research Genome Engineering Core Facility (RRID:SCR_021729)
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Mass Spectrometry
Proteomics
Michael Washburn,Michaella Rekowski
3901 Rainbow Blvd
Hemenway building room 1058
Kansas City, KS 66160 - United States of America
RRID:SCR_025893
Mass spectrometry based proteomics
This facility provides services outside its institution
This facility provides consulting outside its institution
10/11/2024
Clinical Imaging - Small Animal (X-ray, Ultrasound, microCAT, MRI)
Functional Brain Imaging
Magnetic Resonance Imaging (MRI)
Justine Karungi
3901 Rainbow Blvd.
Kansas City, KS 66160 - United States of America
http://www.kumc.edu/school-of-medicine/hoglund-brain-imaging-center.html
RRID:SCR_017920
The Hoglund Brain Imaging Center (HBIC) occupies a free-standing 11,500 sq. ft. research-based imaging facility on the University of Kansas Medical Center (KUMC) campus. HBIC provides outstanding imaging capabilities, including magnetic resonance imaging, magnetoencephalolgraphy, electroencephalography, magnetocardiography, and ultrasound, to complement the existing biomedical research community at KUMC and nearby universities. HBIC brings scientists from diverse disciplines such as neurology, neurosurgery, radiology, nephrology, cardiology, psychiatry, psychology, preventive medicine, nursing, physiology, biochemistry, anatomy, medical physics, engineering, and computer science together in a highly collaborative and integrative environment. A further strength of the HBIC is its close proximity to the KU Hospital, providing optimal access for research participants.
HBIC provides an outstanding team of world-class scientists who are developing new imaging methods, a group of excellent staff who support collaborations, and a unique combination of state-of-the-art equipment. As well as brain development, aging, and decision making, the Hoglund Brain Imaging Center supports investigations into Alzheimer's disease, traumatic brain injury, stroke, multiple sclerosis, cancer, polycystic kidney disease, obesity, diabetes, anxiety disorders, depression, smoking and addiction and several others.
The HBIC provides considerable support to investigators through a strong faculty with broad expertise in cognitive neuroscience, neurobiology, biomedical physics, and computing, together with a support team of technologists, nurses, research associates, and research assistants. Through strong collaborations, these individuals assist with study design, collection of data, analysis, and interpretation of results. The HBIC also supports investigators with new technique development, feasibility studies, pilot funding, preparing grant applications and manuscripts, and compliance.
This facility provides services outside its institution
This facility provides consulting outside its institution
12/05/2017
LC-MS
Nano-LC-MS -complex Mixtures
Sample Preparation
Proteomics
Sean Riordan
2411 Holmes St
MG-101
Kansas City, MO 64108 - United States
RRID:SCR_027679
Other CIDs:1S10OD032451-01A1
The UMKC Proteomics Core Facility is a federally funded facility committed to advancing scientific research by delivering high-quality proteomic data at competitive rates. Our mission is to empower researchers in the Kansas City area and beyond with accurate, reliable, and timely proteomics analysis contributing to breakthroughs that enhance our understanding of biology and improve human health. Through our dedication to cutting-edge technology, exceptional service, and rigorous quality standards, we strive to become a premier proteomics resource for the scientific community.
This facility provides services outside its institution
This facility provides consulting outside its institution
11/17/2025
Confocal Microscopy
Confocal/ Super Resolution Microscope
Near Super-resolution Confocal Microscopy
Quantum Imaging
STED Nanoscopy
Stem Cells
Widefield Microscopy
Stem Cell
Luis Acevedo Hueso
Riggs Ln,
Overland Park, KS 66212 - United States
Quantum Medical
Quantum Medical Devices, Imaging and Diagnostics.
Microscopy
This facility provides services outside its institution
This facility provides consulting outside its institution
06/20/2025
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