The Great Lakes Genomics Center exists to support researchers developing and using genomic data for ecology and environmental health. We do this by providing sequencing and gene expression technologies and service for ecology, environment and human health researchers, as well as a support system for analysis and discussion of issues surrounding the use of genomic technologies for environmental health.
We are a small facility that focuses on applying genomic techniques to environmental and ecological research. We provide access to instruments and training needed for genomic research as well as sequencing and ddPCR. Our facility contains an Illumina MiSeq, BioRad ddPCR system, RT-PCR machines, and a BioTek Synergy H4 multi-mode plate reader. Available bioinformatics software includes CLC-Genomics Workbench and DNAStar, and we have access to state of the art computational resources both in lab and on the main UW Milwaukee campus.

The Bioinformatics Core offers bioinformatics consultation, training, and data analysis to help investigators analyze and understand the large-scale biological datasets required from different platforms, including next generation sequencing, array-based technologies and mass spectrometry. We collaborate closely with other shared resources on joint projects and offer end-to-end bioinformatics assistance, spanning experiment design, data analysis, result interpretation and delivery. Our capabilities encompass the development and operation of standard and advanced data processing pipelines, covering tasks such as bulk next-generation sequencing analysis (e.g., RNA-Seq, DNA-Seq, methyl-Seq, and ChIP-Seq), single-cell analysis, transcriptome and genome annotation, variant detection and interpretation and metagenomics.
Our team members have extensive experience in bioinformatics, biostatistics, genomics, genetics, transcriptomics and translational informatics in human, animal and microbial systems. Our expertise includes big data analysis, statistical analysis, machine learning, neuro network, software development and high-performance computing. Our approach prioritizes scientific collaboration, going beyond mere service provision to leverage our skills and knowledge for the success of your projects.
Furthermore, we offer support for grant applications, including key personnel involvement, support letters, and analytical method write-ups.

Core forms network of laboratories dedicated to advancing biomedical research by providing access to specialized services, advanced equipment, and expert staff.
Services include Bioinformatics, Biorepository, Flow Cytometry, Grant Application Support, Histology, Hybridoma, Microscopy, Molecular and Single Cell Biology, Protein Shared Instrumentation,Thrombosis and Hemostasis, Viral Vector.

The Biostatistics Shared Resource supports the spectrum of cancer-related research activities, including: experimental design, sample size calculation, randomization, analysis plans, data analysis, grant and manuscript preparation, full clinical trial support, and innovative targeted methods development.

This multidisciplinary facility provides access to human stem cells, 3D organoids, and other human-relevant disease models to support more predictive drug discovery, improved safety and toxicity assessment, and deeper mechanistic insight. Leveraging organoid and microphysiological platforms, the core enables next-generation therapeutics and “clinical trial-in-a-dish” approaches that advance biomedical innovation and precision medicine.

For information, email: organoids@mcw.edu

The MCW Cancer Center Cell Therapy Shared Resource (CTSR) focuses on curing cancer through innovative and effective cell therapies. The CTSR provides 1) state-of-art processing and production of cell therapy products for clinical use, 2) expertise in the translation of cellular therapies to the clinic, and 3) cutting-edge instrumentation supporting the development of novel immunotherapy strategies and insights on mechanisms of action for effective therapies.

The SBSR consists of the Protein Purification unit and the Structure Determination unit. The Protein Purification unit produces homogeneous, high-quality proteins well suited for downstream biophysical studies and structure determination. The Structure Determination unit employs X-ray crystallography, Cryo-EM, and advanced AI-assisted analytical tools for structure determination and imaging.