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All Facilities >> Medical College of Wisconsin >> MCW-Mellowes Center for Genomic Sciences and Precision Medicine (Genomics / Genome Analysis and Technologies)
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8701 Watertown Plank Rd.
HRC 5th Floor
Milwaukee, WI 53226
United Stateshttps://www.mcw.edu/departments/genomic-sciences-and-precision-medicine-center-gspmccite this facility
Dr. Angela Mathison
Last Updated: 02/10/2024
Saving lives and improving the wellness of individual citizens and the community by advancing genomic sciences and precision medicine.
Pioneering the fields of Omics, Data Science, and Systems Biology to discover and innovate across our four programs.
The Mellowes Center has its roots in the launch of the Human Genome Project and the 1999 founding of the MCW Human and Molecular Genetics Center. The Mellowes Center uses state-of-the-art whole genome sequencing technologies not only to investigate how gene variants impact gene expression but also to define genetic variants associated with both rare and common disease, embryonic development, and the effects of environmental factors and drugs upon gene expression and disease.
Services are offerred outside of Medical College of Wisconsin
Consulting is offerred outside of Medical College of Wisconsin
Data Analysis And Interpretation
Data Processing And Interpretation
Genome/Transcriptome Assembly And Annotation
Agilent 5200 Fragment Analyzer System
Fragment Analyzer System allows you to separate 12 samples in parallel in as little as 15 minutes. [Product Link]
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BioTek Synergy LX Multi-Mode Microplate Reader
Microplate reader with an optic design that provides accurate data in absorbance, fluorescence and luminescence detection modes, enabling many common assays including nucleic acid and protein quantification, ELISA, BCA, Bradford and cell viability. [Product Link]
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Eppendorf 5430R Microcentrifuge
Cross-over Centrifuge 5430 and 5430 R combine the best features of a microcentrifuge (small footprint) and multipurpose centrifuge (versatility) in one instrument. These centrifuges spin rotors for Eppendorf tubes and PCR strips as you would expect from any microcentrifuge. But that's not all. In a compact size, Centrifuge 5430 and 5430 R also accommodate rotors for microplates and 15/50 mL conical tubes. Now, the rotor program has been expanded with additional Eppendorf QuickLock rotors. This includes 48-place rotors (1.5/2.0 mL), a 16-place rotor for Eppendorf Tubes 5.0 mL and a swing-bucket rotor (24 × 1.5/2.0 mL). With their unmatched versatility, Centrifuge 5430 and Centrifuge 5430 R are the flagship products among the Eppendorf microcentrifuge portfolio. Available as keypad or knob variant [Product Link]
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Illumina MiSeq System
Access focused applications such as targeted resequencing, metagenomics, small genome sequencing, targeted gene expression profiling, and more. MiSeq reagents enable up to 15 Gb of output with 25 million sequencing reads and 2 × 300 bp read lengths. [Product Link]
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Illumina NovaSeq 6000 Sequencing System
Unleashes groundbreaking innovations that leverage our technology Now you can get scalable throughput and flexibility for virtually any sequencing method, genome, and scale of project. [Product Link]
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Miltenyi gentleMACS Octo Dissociator with Heaters Tissue Dissociator
Benchtop instrument for fully automated and standardized tissue dissociation or homogenization of up to eight samples. Equipped with eight individual heating units and gentleMACS Programs. [Product Link]
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Perkin Elmer Chemagic 360 Genetic isolation Workstation
Nucleic Acid Extractor for Medium to High Throughput. Based on our patented chemagen magnetic bead technology the chemagic 360 instrument represents the best solution for nucleic acid isolation in a huge variety of research market segments including but not limited to Biobanking/Human Genetics, HLA Typing, Virus and Bacteria Detection. Experience the revolutionary compact benchtop design of our newly developed chemagic 360 Nucleic Acid Extractor. Based on the well-established chemagen Technology, the system offers a flexible solution for different sample processing and throughput needs. Configurable with three kinds of chemagic Rod Heads (see table below) the system can process sample volumes from 10 ?l 10 ml. [Product Link]
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Perkin Elmer Zephy G3 NGS liquid handler
Benchtop liquid handler designed to automate construction of 48 to 96 next generation sequencing libraries per day. [Product Link]
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Qiagen Tissue Lyser II RNA/DNA Purification
RNA and DNA purification analyzer that disrupts biological samples through high speed shaking in plastic tubes with stainless steel, tungsten carbide, or glass beads. [Product Link]
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Sage Science BluePippin system
Used for DNA Size Selection for Next-Gen Sequencing, with Pulsed-Field (100bp ? 50kb).BluePippin has the DNA capabilities of the Pippin Prep, plus the extra benefit of pulsed-field electrophoresis for resolving and collecting high molecular weight DNA. For long-range genomic applications, high-pass filtering allows users to collect all fragments above a size threshold set by the user. Target sizes or ranges of sizes are entered in software, and fractions are collected in buffer. Up to 5 samples/gel cassette may be run, with no possibility of cross contamination. [Product Link]
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Facility Details
About This Facility
Services and Equipment
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