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All Facilities >> University of Notre Dame >> University of Notre Dame Keck Center for Transgene Research Core Facility
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Transgenics
University of Notre Dame
United Stateshttps://transgene.nd.edu/cite this facility
Francis J. Castellino
Core develops and uses gene-targeting technology to investigate pathophysiological roles of genes of blood coagulation, anticoagulation, and fibrinolytic pathways in hemostasis, with associated relevance to embryonic development, cancer, infection, and inflammation.
Last Updated: 08/13/2024
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https://coremarketplace.org/?FacilityID=2891Institution
Institution ROR ID: https://ror.org/00mkhxb43Keywords:
ABRF, gene-targeting technology, pathophysiological roles of genes, blood coagulation, anticoagulation, fibrinolytic pathways, hemostasis, embryonic development, cancer, infection, inflammation
Resource Type:
access service resource, core facility, service resource
Citation:
University of Notre Dame Keck Center for Transgene Research Core Facility (RRID:SCR_025588)
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Analytical Ultracentrifugation
Antibody Characterization
Automated Liquid Handling
Biological Mechanism
Bioluminsecence Imaging
Circular Dichroism (CD)
Consultation
Crystal Optimization
Data Analysis And Interpretation
Differential Scanning Fluorimetry (DSF)
DNA Analysis
Drug Discovery
Experimental Design
Fragment-based Drug Discovery
Fragment-based Screening
High-throughput Screening
Image Aquisition
Image Processing And Analysis
Isothermal Titration Calorimetry (ITC)
Molecular Imaging
Monoclonal Antibody
Phosphor Imaging
Protein Crystallization
Protein Extraction/Purification
Protein Production
Protocol Development
Real-time qPCR
RNA analysis
Sample Preparation
Shared Instrumentation Oversight & Maintenance
Small Molecule Compound Screening
Spectroscopy
Structural Biology
Surface Plasmon Resonance (SPR)
Thermal Analysis
Training
X-Ray Crystallography
Biophysics
Giselle Jacobson
446C Stepan Chemistry Hall
Notre Dame, IN 46556 - United States
RRID:SCR_023867
Other CIDs:1S10OD028553-01
1S10OD036273-01
1S10OD038334-01
The Biophysics Instrumentation Core (BIC) Facility offers sophisticated instrumentation dedicated to characterizing biomolecular conformations and interactions, as well as equipment for the isolation and purification of macromolecules for subsequent detailed biophysical analysis.
This facility provides services outside its institution
This facility provides consulting outside its institution
04/29/2026
10X Genomics Single Cell
10x Genomics Xenium Spatial Transcriptomics
ABI3730XL Sanger Sequencing And Fragment Analysis
Bioinformatics Analysis
BluePippin Automated Size Selection
Custom And Specialty NGS Workflows
High-intensity Acoustic Shearing
Illumina MiSeq Sequencing
Illumina NextSeq Sequencing
Illumina RNA/DNA NGS Library Construction
RNA/DNA Quality Control
Visium HD Spatial Transcriptomics
Melissa Stephens
019 Galvin Life Science
Notre Dame, IN 46556 - United States
RRID:SCR_025555
The Genomics & Bioinformatics Core Facility (GBCF) at Notre Dame serves a diverse research community that spans basic biomedical research in human disease, vector disease research, population genomics, and environmental genomics. Utilizing Illumina sequencing, single-cell analysis, and spatial transcriptome analysis, we offer comprehensive solutions designed to acquire data for a broad range of applications including metagenomics, cancer genomics, microbial genomics, transcriptomics, and epigenomics for both model and non-model systems. Applying robust bioinformatics tools and biocomputing resources, we offer guidance and analysis workflows specifically tailored to your needs.
This facility provides services outside its institution
This facility provides consulting outside its institution
02/11/2025
Mass Spectrometry
RRID:SCR_025596
Core provides analysis of large and small molecules using several ionization methods, low or high resolution, hyphenated techniques, proteomics, and metabolomics.
This facility does not provide services outside its institution
This facility does not consult outside its institution
08/13/2024
Magnetic Resonance
RRID:SCR_025599
Core supports research in chemistry, biochemistry, molecular biology, engineering and related fields. The MRRC operates six solution-state NMR spectrometers (400 to 800 MHz), a solid-state 300 MHz NMR instrument, and an X-band EPR spectrometer. Most instruments are equipped with sample changers for increased sample throughput.
This facility does not provide services outside its institution
This facility does not consult outside its institution
08/13/2024
Animal Facilities (Zebrafish, Fly, Mouse, Vivarium)
RRID:SCR_025552
Home to virtually all laboratory animals. Services include Procurement, Animal care, Breeding, Training,Limited procedures for research.
This facility does not provide services outside its institution
This facility does not consult outside its institution
08/13/2024
2D & 3D Illustration
3D & 4D Image Processing Stations
3D Visualization
Analysis Workstations
Animal Training
Biochemical Analysis
Biological Mechanism
Biological photography/Photomicrography
Body Composition
Cell Imaging
Clinical Imaging - Small Animal (luminescence/fluorescence)
Clinical Imaging - Small Animal (X-ray, Ultrasound, microCAT, MRI)
Computed Tomography (CT)
Computer-assisted Neuron Tracing And Analysis
Confocal Microscope With FCS/FLIM Capabilities
Confocal Microscopy
Confocal/ Super Resolution Microscope
Consultation
Consultations
Correlative Light Electron Microscopy
Cryostat Histology
Customized Protocols
Data Analysis
Data Analysis And Interpretation
Data Processing
Data Processing And Interpretation
Data Visualization
Deconvolution
Drug Discovery
Electron Microscopy
Fluorescence Lifetime
Fluorescence Microscope With Optical Sectioning Capability
Focused Ion Beam (FIB)
Functional Brain Imaging
H&E Staining
Hi
Imaging (Cell, Molecular, PET, Translational)
Sarah Chapman
340 McCourtney Hall
Notre Dame, IN 46556 - United States
RRID:SCR_022743
The NDIIF provides an integrated suite of sophisticated microscopes and imaging stations that enable expert users to address the most complex modern research problems and, equally important, expert staff, including technicians and research specialists, to guide the non-expert users. The facility offers imaging expertise in Electron Microscopy, Optical Microscopy, In Vivo Imaging, and Histology.
This facility provides services outside its institution
This facility provides consulting outside its institution
07/14/2023
Facility Details
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