The CoreMarketplace: VAI

Full service Next Generation Sequencing, single cell Genomics, and Spatial Transcriptomics facility. Provides experimental design support, library generation, and Illumina and Nanopore Sequencing.

Facility Policies

Services are offerred outside of Van Andel Institute

Consulting is offerred outside of Van Andel Institute

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Services offered:

Reduced Representation Bisulfite Sequencing

Sequencing - Next Generation Sequencing (NGS)

Single-cell Sequencing

Spatial Transcriptomics

Whole Exome Sequencing

Whole Genome Sequencing

Facility Equipment

10X Genomics Chromium X

single cell nanofluidic instrument

10X Genomics CytAssist

Histology/Spatial Transcriptomics

Element Aviti

Sequencing Instrument

Element Aviti

Sequencing Instrument

Illumina iScan System

BeadArray/Microarray

Illumina NovaSeq 6000

Sequencer

Nanostring GeoMx DSP Spatial Profiler

Spatial Transcriptomics

No additional equipment has been listed

(To see more facility information, click the in the upper right)

Publications

Publications associated with this facility (Click To View):

1.) Vatsa N, Brynildsen JK, Goralski TM, Kurgat K, Meyerdirk L, Breton L, DeWeerd D, Brasseur L, Turner L, Becker K, Gallik KL, Bassett DS, Henderson MX (2024 Oct 22). Network analysis of α-synuclein pathology progression reveals p21-activated kinases as regulators of vulnerability bioRxiv, (), 2024.10.22.619411. . PMCID: 11526907.

2.) Xue Z, Qin L, Xuan H, Luo K, Huang M, Xie L, Su Y, Xu L, Harsh J, Dale B, Shi X, Chen X, Kaniskan HÜ, Jin J, Wen H (2024 Aug 28). A potent and selective ENL degrader suppresses oncogenic gene expression and leukemia progression Science Advances, 10(35), eado1432. . PMCID: 11352836.

3.) Guak H, Weiland M, Ark AV, Zhai L, Lau K, Corrado M, Davidson P, Asiedu E, Mabvakure B, Compton S, DeCamp L, Scullion CA, Jones RG, Nowinski SM, Krawczyk CM (2024 Jul 24). Transcriptional programming mediated by the histone demethylase KDM5C regulates dendritic cell population heterogeneity and function Cell reports, 43(8), 114506. . PMCID: 11416765.

4.) Kochmanski J, Virani M, Kuhn NC, Boyd SL, Becker K, Adams M, Bernstein AI (2024 Apr 29). Developmental origins of Parkinson’s disease risk: perinatal exposure to the organochlorine pesticide dieldrin leads to sex-specific DNA modifications in critical neurodevelopmental pathways in the mouse midbrain bioRxiv, (), 2024.04.26.590998. . PMCID: 11092502.

5.) Chomiak AA, Tiedemann RL, Liu Y, Kong X, Cui Y, Wiseman AK, Thurlow KE, Cornett EM, Topper MJ, Baylin SB, Rothbart SB (2024 Mar 27). Select EZH2 inhibitors enhance viral mimicry effects of DNMT inhibition through a mechanism involving NFAT:AP-1 signaling Science Advances, 10(13), eadk4423. . PMCID: 10971413.

6.) Goralski TM, Meyerdirk L, Breton L, Brasseur L, Kurgat K, DeWeerd D, Turner L, Becker K, Adams M, Newhouse DJ, Henderson MX (2024 Mar 26). Spatial transcriptomics reveals molecular dysfunction associated with cortical Lewy pathology Nature Communications, 15(), 2642. . PMCID: 10966039.

7.) Tiedemann RL, Hrit J, Du Q, Wiseman AK, Eden HE, Dickson BM, Kong X, Chomiak AA, Vaughan RM, Hebert JM, David Y, Zhou W, Baylin SB, Jones PA, Clark SJ, Rothbart SB (2024 Feb 16). UHRF1 ubiquitin ligase activity supports the maintenance of low-density CpG methylation. bioRxiv : the preprint server for biology, (), . . PMID: 38405904.

8.) Booms A, Pierce SE, van der Schans EJ, Coetzee GA (2024 Jan 17). Parkinson’s disease risk enhancers in microglia iScience, 27(2), 108921. . PMCID: 10845915.

9.) Panzeri I, Fagnocchi L, Apostle S, Tompkins M, Wolfrum E, Madaj Z, Hostetter G, Liu Y, Schaefer K, Chih-Hsiang Y, Bergsma A, Drougard A, Dror E, Chandler D, Schramek D, Triche TJ Jr, Pospisilik JA (2023 Sep 15). Developmental priming of cancer susceptibility bioRxiv, (), 2023.09.12.557446. . PMCID: 10515831.

10.) Pérez-Mojica JE, Enders L, Lau KH, Lempradl A (2023 Sep 7). Single-embryo RNA sequencing for continuous and sex-specific gene expression analysis on Drosophila STAR Protocols, 4(3), 102535. . PMCID: 10493594.

11.) Paul EN, Carpenter TJ, Fitch S, Sheridan R, Lau KH, Arora R, Teixeira JM (2023 Jul 3). Cysteine-rich intestinal protein 1 is a novel surface marker for human myometrial stem/progenitor cells Communications Biology, 6(), 686. . PMCID: 10317972.

12.) Goralski T, Meyerdirk L, Breton L, Brasseur L, Kurgat K, DeWeerd D, Turner L, Becker K, Adams M, Newhouse D, Henderson MX (2023 May 17). Spatial transcriptomics reveals molecular dysfunction associated with Lewy pathology bioRxiv, (), 2023.05.17.541144. . PMCID: 10245657.

13.) Paul EN, Carpenter TJ, Fitch S, Sheridan R, Lau KH, Arora R, Teixeira JM (2023 Mar 18). Cysteine-Rich Intestinal Protein 1 is a Novel Surface Marker for Myometrial Stem/Progenitor Cells bioRxiv, (), 2023.02.20.529273. . PMCID: 10054937.

(To see more facility information, click the in the upper right)

Associations

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Metadata

Links

All the links listed resolve to this core profile

https://coremarketplace.org/?FacilityID=1600
https://coremarketplace.org/RRID:SCR_022913

Institution

Institution ROR ID: https://ror.org/00wm07d60

SciCrunch Data Imports (data maintained by https://scicrunch.org)

Keywords:

USEDit, ABRF, Next Generation Sequencing, single cell Genomics, Spatial Transcriptomics facility

Resource Type:

service resource, access service resource, core facility

Citation:

Van Andel Institute Genomics Core Facility (RRID:SCR_022913)

VAI - Genomics Core (Genomics / Genome Analysis and Technologies)

Primary Contact:

Facility RRID

Facility Details

Facility Policies

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Services offered:

Facility Equipment

(To see more facility information, click the in the upper right)

Publications

(To see more facility information, click the in the upper right)

Associations

(To see more facility information, click the in the upper right)

Metadata

SciCrunch Data Imports (data maintained by https://scicrunch.org)

Facility Profile QR Code (links to this profile)

(To see more facility information, click the in the upper right)

Contact Marie Adams

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VAI - Genomics Core

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