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All Facilities >> University of Rhode Island >> RI-INBRE Molecular Informatics Core (Data Science)
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7 Greenhouse Road, College of Pharmacy
Kingston, RI 02881
United Stateshttps://web.uri.edu/riinbre/mic/cite this facility
Christopher Hemme
Last Updated: 02/11/2025
The RI-INBRE Molecular Informatics Core provides services in sequencing (Illumina MiSeq, Sanger), bioinformatics analysis, access to molecular modeling software, and development of virtual reality applications. We are an NIH Data Sciences Core for Biomedical Research serving the Rhode Island community and are able to provide services to both biomedical and environmental researchers.
is_active:
Yesbudget_end:
04/30/2025date_added:
05/11/2024agency_code:
NIHfiscal_year:
2024project_num:
2P20GM103430-24award_amount:
$210,658.00budget_start:
05/09/2024org_name:
UNIVERSITY OF RHODE ISLANDorg_state:
RIorg_country:
UNITED STATESorg_zipcode:
028810811primary_duns:
144017188abstract_text:
RI-INBRE Data Science – Molecular Informatics Core (MIC) Project Summary The overarching goal of the Rhode Island IDeA-Network of Biomedical Research Excellence (RI-INBRE) program is to improve institutional capacity for biomedical research excellence and student experiential training in the State of Rhode Island. The RI-INBRE Data Science – Molecular Informatics Core (MIC) provides biomedical data science services to RI-INBRE and the broader research community. In this renewal application, the MIC will restructure to reflect the expanded role of data science in biomedical research. The focus areas of the MIC will extend well beyond bioinformatics and include biomedical data science, next-generation sequencing, and 3D science visualization. Our model allows for future growth into new research areas, such as cloud computing and machine learning/artificial intelligence, to meet the current and future research needs of the RI biomedical community. We will provide bioinformatics and biomedical data science expertise, consulting, analysis, and training to investigators in and out of the RI-INBRE network. Given the rapid pace of emerging data science technologies, an essential goal of the MIC is to keep investigators and students informed of current technologies and methodologies via multiple outreach and training efforts. The MIC will collaborate with the RI- INBRE Centralized Research Core Facility to streamline and unify the omics data generation and analysis pipelines to increase efficiency and improve user experience. The MIC will serve as a liaison between users and other data science cores in the state and regional partners to ensure network investigators are apprised of available services and have access to a comprehensive slate of data science tools. These MIC initiatives will provide biomedical investigators with critical data science resources and training during the renewal period. This will promote biomedical research career development and collaborations that will fuel economic growth in the biotechnology, pharmaceutical, and life sciences industries in RI.project_title:
Data Science Corecontact_pi_name:
HEMME, CHRISTOPHER LEEtotal_cost:
$210,658.00Services are offerred outside of University of Rhode Island
Consulting is offerred outside of University of Rhode Island
Computational - Bioinformatics
Data Analysis And Interpretation
Genome/Transcriptome Assembly And Annotation
Applied Biosystems 3130 Genetic Analyzer
The Applied Biosystems® 3130 (4-capillary) Genetic Analyzer is an electrophoresis device for the low to medium throughput laboratories that provides industry-leading performance and sophisticated automation capabilities. It can run a wide variety of sequencing and fragment analysis applications including microsatellite analysis, AFLP, LOH, SNP validation, and SNP screening. Maintenance time is reduced by eliminating manual syringe washing and filling with automated polymer delivery. The 3130 can increase your data quality for sequencing and fragment analysis applications – longer read length, and higher resolution with shorter run times. The 3130 can increase laboratory productivity and turnaround time by processing 96- or 384-well plates with a four-capillary array. [Product Link]
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BioAnalyzer 2100
2100 Bioanalyzer system is an established automated electrophoresis tool for the sample quality control of biomolecules. The 2100 Bioanalyzer instrument, together with the 2100 Expert Software and Bioanalyzer assays, provide highly precise analytical evaluation of various samples types in many workflows, including next generation sequencing (NGS), gene expression, biopharmaceutical, and gene editing research. Digital data is provided in a timely manner and delivers objective assessment of sizing, quantitation, integrity and purity from DNA, RNA, and proteins. Minimal sample volumes are required for an accurate result, and the data may be exported in a many different formats for ease-of-use. [Product Link]
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Illumina MiSeq System
Access focused applications such as targeted resequencing, metagenomics, small genome sequencing, targeted gene expression profiling, and more. MiSeq reagents enable up to 15 Gb of output with 25 million sequencing reads and 2 × 300 bp read lengths. [Product Link]
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We have access to the URI Bluewaves computing cluster and cloud resources for larger scale bioinformatics analyses.
We have a small lab with two PC's and 3 laptops used for molecular modeling (2 Spartan licenses, 2 Molecular Operating Environment licenses) and VR/AR app development (HTC Vive, HTC Cosmos, Looking Glass holodisplay, etc). We also have access to the College of Pharmacy 3D printer for printing of macromolecule structures.
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https://coremarketplace.org/?FacilityID=3Institution
Institution ROR ID: https://ror.org/013ckk937Keywords:
Analysis, interpretation, nucleotide, amino acid, sequence, protein, domain, structure, service, 3D visualization, modeling, USEDit
Resource Type:
core facility, service resource, access service resource
Citation:
Rhode Island INBRE Molecular Informatics Core Facility (RRID:SCR_017685)
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Facility Details
About This Facility
Services and Equipment
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Awards & Associations
Metadata
Other Facilities at this Institution: