analytical ultracentrifuges (Beckman XL-I and XL-A) XL-A

Centrifuge with in-solution characterization of proteins, oligomers, aggregates, particles, colloids, and small structures. It allows for In-solution testing in native conditions. It measures the relative change in the distribution of molecular weights, providing an efficient way to measure heterogeneity, stoichiometry and self-associating systems. [Product Link]

RRID:SCR_019567

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BioTek Synergy Neo2 Hybrid Multi-Mode Microplate Reader

Microplate reader that is designed for a screening laboratory and combines variable bandwidth quad monochromators, sensitive high transmission filter-based optics, laser TRF and up to 4 PMTs to provide fast measurements. [Product Link]

RRID:SCR_019765

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Formulator by Formulatrix liquid handler for preparing crystallization reservoirs

Liquid handler specifically designed for Protein Crystallography that uses patented microfluidic technology to dispense up to 34 different ingredients. A 96-nozzle dispensing chip can dispense any volume of any ingredient of any viscosity into any well. [Product Link]

RRID:SCR_019920

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General Electric AKTA FPLC System, Protein Purification System

Purification system intended for microgram-scale protein purifications in Tricorn columns up to milligram-scale using HiTrap and HiScreen columns. For fast protein liquid chromatography of tens of grams of protein,can be used with flow rates up to 150 mL/min. This high flow rate is necessary when working with high-flow resins in large columns. Columns can even be packed at flow rates as high as 300 mL/min. System reduces hands-on time so that you can spend less time purifying proteins and more time focusing on your results. Easily switch between different users and applications. To get you up and running quickly, methods are easily created by dragging and dropping predefined templates in UNICORN 7. Purification of protein to sufficiently high yield and purity can be a time- and resource-consuming process. To address fast and efficient protein purification, Can be set up in different ways to handle multistep purification. With an additional column valve up to 10 columns can be connected enabling automation of several samples and steps. [Product Link]

RRID:SCR_019958

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Jasco 1500 1500

J-1500 allows for the maximum flexibility to upgrade your CD system with different measurement techniques. While the standard measurement modes are CD, LD, and absorbance, up to four simultaneous modes can be measured when combined with a wide range of sampling accessories. These accessories can measure a variety of samples, from liquids to films to solid-states. Temperature control systems can be coupled with multi-position cells to run thermal melts, providing researchers with CD and thermodynamic data sets for conformational and folding studies. Automated high-throughput CD can obtain measurements on up to 192 samples without user intervention, saving both time and money. Kinetic and protein dynamics studies can be performed with our dedicated stopped-flow systems that can measure both CD and fluorescence. The wavelength range has also been significantly extended, allowing measurements to be obtained in both the vacuum-UV and NIR spectral regions using the standard PMT detector (163 950 nm) and an optional InGaAs detector (up to 1600 nm). Additional features now allow researchers to optimize their parameter specifications in order to obtain data with the highest resolution and S/N performance for a specific application set. [Product Link]

RRID:SCR_020147

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Microcal ITC 200 Isothermal Titration Calorimeter

Isothermal titration calorimeter for label free, in solution, study of biomolecular interactions. It delivers measurement of binding parameters with minimum of 10 ug sample. [Product Link]

RRID:SCR_018590

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Cytiva Biacore T-200 SPR

Surface plasmon resonance