Core provides expertise in Next Generation Sequencing (NGS) technologies to provide users with full spectrum of genomic services, including microarray analysis (ie genotyping and methylation arrays), NGS library preparation, short-read and long-read sequencing, genotyping.

GLP-certified animal pathology laboratory house within A*STAR iCORE provides research facilitation to A*STAR Research Institutes, Universities, Health sectors, Major pharmaceutical companies, and SMEs in Singapour. Staffed by highly experienced professionals and supported by robust infrastructures, the laboratory delivers valuable pathological insights that contribute to research projects, grant applications, and scientific publications across diverse disciplines. The laboratory was previously known as Advanced Molecular Pathology Laboratory (AMPL).

iCORE Proteomics, previously known as Advanced Proteomics Platform (A~PROMPT) provides proteomics service for research in Singapore. Services include instrumentation use,
Protein ID, Whole proteome ID, Targeted proteomics, Labelled free quantitation proteomics (LFQ), TMT proteomics, Post-Translational Modifications proteomics (phospho/Ubi PTM), Clinical proteomics, DIA-proteomics.

Core offers expertise and support in imaging, light microscopes and techniques for imaging across the length scales a at high spatiotemporal resolution. Provides regular practical training courses in microscopy and image analysis.

Core provides service for one-stop spatial biology solutions from sample handling to high-end spatial data generation. Serves as a specialized bridge between laboratory research and clinical application (immuno-patho translation). Offers services in general histology, spatial transcriptomics and spatial proteomics. It primarily focuses on experiment designing, optimisation, spatial proteomic staining and imaging, allowing assay customisation, development and validation.