Cogentech's Genomic Core Facility (GU) provides professional support for the entire workflow of our customer’s research projects, from counseling on experimental design to functional interpretation of results. Support includes the identification of the most suitable methodology to achieve the experimental aim, quality control of nucleic acid, generation of indexed fragment library, sequencing according to experimental needs and bioinformatic support for selected applications. Customized protocols can be set-up as well. Sequencing data are delivered using a password protected user-friendly web interface. The laboratory is ISO9001 certified.

Cogentech's Proteomics and Metabolomics (P&M) Core Facility provides a full infrastructure for the identification, characterization and quantification of proteins, metabolites and lipids. The Facility includes several instrumental platforms for the separation of those molecules starting from simple or complex samples. The proteomics, metabolomics and lipidomics analysis rely on state-of-the art mass spectrometry coupled with liquid chromatography (LC-MS/MS).

Cogentech's Biological Research Facility (BRF) provides an animal facility in which laboratory mice are maintained and bred for different research programs. The Faciity is committed to apply the Three Rs principle (Replacement, Reduction, Refinement) and pay particular attention to ensure animal welfare. The laboratory is ISO9001 certified.

Cogentech's Integrated Genomics Core Facility (IGU) consists of three state-of-the-art units: Molecular Biology and Sequencing, Histopathology and Bioinformatics. The Molecular Biology group provides expertise in various fields of application: nucleic acid extraction from different matrices, ddPCR and various types of sequencing (customised gene panels, Lowpass WGS, WES, WGS, total RNA-Seq, mRNA Seq, TCR-Seq, 16S Metagenomic Seq, ATAC-Seq, genome-wide methylation profiling). The Bioinformatics unit provides pipelines for the analysis of data produced by all sequencing workflows. In addition, it provides its expertise for the implementation and development of customised pipelines. Finally, the Histopathology unit offers services for slide preparation and staining, image digitisation and laser-capture microdissection. The laboratory is ISO9001 certified.

Cogentech's DNA Sanger Sequencing (DSS) Core Facility offers standard DNA sequencing and assistance for projects using on Sanger sequencing. We also offer the possibility to use fragment analysis for various applications, providing assistance in the pre-and post-analytical phase. The laboratory is ISO9001 certified.

Cogentech's Quantitative PCR (QPCR) Core Facility provides the entire service: from project design, assay selection and development, to data analysi for quantitative analysis of any specific target sequence for gene expression, copy number variation or variant analysis, in low and high-throughput mode. The facility provides analysis using both Real time QPCR and digital PCR. Special protocols for small amounts of starting material have been implemented. The laboratory is ISO9001 certified.

Cogentech's Histopathology (HP) Core Facility provides the entire service: from consultation, to tissue trimming and embedding, cutting, staining, photographic documentation for the evaluation and characterization of normal and pathological tissues from any kind of experimental model system. We also provide Optimization of protocols for new stains or biological specimen. The laboratory is ISO9001 certified.