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All Facilities >> University of California, San Diego >> UCSD-CMM-Electron Microscopy Core (Microscopy (Electron, Fluorescence, Optical))

UCSD-CMM-Electron Microscopy Core (Microscopy (Electron, Fluorescence, Optical))

Facility Details

About This Facility

Services and Equipment

Publications

Awards & Associations

Metadata

Other Facilities at this Institution:

UCSD - Skaggs School of Pharmacy NMR Facility

UCSD IGM Genomics Center

University of California, San Diego

Cellular & Molecular Medicine, GPL room 218A, 9500 Gilman Drive

La Jolla, CA 92093

United States of America

https://emcore.ucsd.edu/

cite this facility

Primary Contact:

Guillaume Castillon

Last Updated: 02/24/2022

Facility RRID

RRID:SCR_022039

Additional Citation Identifiers

S10OD023527

Facility Details

The UCSD Cellular and Molecular Medicine Electron Microscopy core provides services in sample preparation and imaging by Transmission Electron Microscopy and Correlative Light and Electron Microscopy.

Facility Policies

Services are offerred outside of University of California, San Diego

Consulting is offerred outside of University of California, San Diego

(To see more facility information, click the in the upper right)

Services offered:

Consultations

Correlative Light Electron Microscopy

Electron Microscopy

Image Aquisition

Immuno Electron Microscopy

Microscopy

Microtomy/Electron

Sample Preparation

Transmission Electron Microscopy

Facility Equipment

TECNAI SPIRIT BIOTWIN transmission Electron Microscope
JEOL JEM 1400 plus transmission Electron Microscope

(To see more facility information, click the in the upper right)

Publications

Publications associated with this facility (Click To View):

1.) González-Gamboa I, Caparco AA, McCaskill J, Fuenlabrada-Velázquez P, Hays SS, Jin Z, Jokerst JV, Pokorski JK, Steinmetz NF (2024 Mar 26). Inter-coat protein loading of active ingredients into Tobacco mild green mosaic virus through partial dissociation and reassembly of the virion Scientific Reports, 14(), 7168. . PMCID: 10965923.

2.) Xia W, Veeragandham P, Cao Y, Xu Y, Rhyne TE, Qian J, Hung CW, Zhao P, Jones Y, Gao H, Liddle C, Yu RT, Downes M, Evans RM, Rydén M, Wabitsch M, Wang Z, Hakozaki H, Schöneberg J, Reilly SM, Huang J, Saltiel AR (2024 Jan 29). Obesity causes mitochondrial fragmentation and dysfunction in white adipocytes due to RalA activation Nature Metabolism, 6(2), 273-289. . PMCID: 10896723.

3.) Goldberg G, Coelho L, Mo G, Adang LA, Patne M, Chen Z, Garcia-Bassets I, Mesci P, Muotri AR (2023 Dec 21). TREX1 is required for microglial cholesterol homeostasis and oligodendrocyte terminal differentiation in human neural assembloids. Molecular psychiatry, (), . doi: 10.1038/s41380-023-02348-w. PMID: 38129659.

4.) Cobián Güemes AG, Ghatbale P, Blanc AN, Morgan CJ, Garcia A, Leonard J, Huang L, Kovalick G, Proost M, Chiu M, Kuo P, Oh J, Karthikeyan S, Knight R, Pogliano J, Schooley RT, Pride DT (2023 Dec 14). Jumbo phages are active against extensively drug-resistant eyedrop-associated Pseudomonas aeruginosa infections. Antimicrobial agents and chemotherapy, 67(12), e0065423. . PMID: 37931230.

5.) Venkatraman K, Lee CT, Garcia GC, Mahapatra A, Milshteyn D, Perkins G, Kim KY, Pasolli HA, Phan S, Lippincott-Schwartz J, Ellisman MH, Rangamani P, Budin I (2023 Dec 11). Cristae formation is a mechanical buckling event controlled by the inner mitochondrial membrane lipidome. The EMBO journal, 42(24), e114054. . PMID: 37933600.

6.) Kaneko K, Liang Y, Liu Q, Zhang S, Scheiter A, Song D, Feng GS (2023 Oct 17). Identification of CD133(+) intercellsomes in intercellular communication to offset intracellular signal deficit. eLife, 12(), . . PMID: 37846866.

7.) Venkatraman K, Lee CT, Garcia GC, Mahapatra A, Milshteyn D, Perkins G, Kim KY, Pasolli HA, Phan S, Lippincott-Schwartz J, Ellisman MH, Rangamani P, Budin I (2023 Sep 2). Cristae formation is a mechanical buckling event controlled by the inner membrane lipidome. bioRxiv : the preprint server for biology, (), . . PMID: 36993370.

8.) Liang W, Sagar S, Ravindran R, Najor RH, Quiles JM, Chi L, Diao RY, Woodall BP, Leon LJ, Zumaya E, Duran J, Cauvi DM, De Maio A, Adler ED, Gustafsson ÅB (2023 Aug 18). Mitochondria are secreted in extracellular vesicles when lysosomal function is impaired Nature Communications, 14(), 5031. . PMCID: 10439183.

9.) Liang W, Sagar S, Ravindran R, Najor RH, Quiles JM, Chi L, Diao RY, Woodall BP, Leon LJ, Zumaya E, Duran J, Cauvi DM, De Maio A, Adler ED, Gustafsson ÅB (2023 Aug 18). Mitochondria are secreted in extracellular vesicles when lysosomal function is impaired. Nature communications, 14(1), 5031. . PMID: 37596294.

10.) Zhao Y, Caron C, Chan YY, Lee CK, Xu X, Zhang J, Masubuchi T, Wu C, Bui JD, Hui E (2023 Jun 13). cis-B7:CD28 interactions at invaginated synaptic membranes provide CD28 co-stimulation and promote CD8(+) T cell function and anti-tumor immunity. Immunity, 56(6), 1187-1203.e12. . PMID: 37160118.

11.) xia W, Veeragandham P, Cao Y, Xu Y, Rhyne T, Qian J, Hung CW, Zhao P, Jones Y, Gao H, Liddle C, Yu R, Downes M, Evans R, Ryden M, Wabitsch M, Reilly S, Huang J, Saltiel A (2023 Jun 2). Obesity-dependent increase in RalA activity disrupts mitochondrial dynamics in white adipocytes Research Square, (), rs.3.rs-2923510. . PMCID: 10312969.

12.) Xia W, Veeragandham P, Cao Y, Xu Y, Rhyne T, Qian J, Hung CW, Zhao P, Jones Y, Gao H, Liddle C, Yu R, Downes M, Evans R, Ryden M, Wabitsch M, Reilly S, Huang J, Saltiel A (2023 Jun 2). Obesity-dependent increase in RalA activity disrupts mitochondrial dynamics in white adipocytes. Research square, (), . . PMID: 37398165.

13.) Sako Y, Sato-Kaneko F, Shukla NM, Yao S, Belsuzarri MM, Chan M, Saito T, Lao FS, Kong H, Puffer M, Messer K, Pu M, Cottam HB, Carson DA, Hayashi T (2023 Apr 21). Identification of a Novel Small Molecule That Enhances the Release of Extracellular Vesicles with Immunostimulatory Potency via Induction of Calcium Influx. ACS chemical biology, 18(4), 982-993. . PMID: 37039433.

14.) Sako Y, Sato-Kaneko F, Shukla NM, Yao S, Belsuzarri MM, Chan M, Saito T, Lao FS, Kong H, Puffer M, Messer K, Pu M, Cottam HB, Carson DA, Hayashi T (2023 Apr 11). Identification of a Novel Small Molecule That Enhances the Release of Extracellular Vesicles with Immunostimulatory Potency via Induction of Calcium Influx ACS Chemical Biology, 18(4), 982-993. . PMCID: 10127211.

15.) Liang W, Diao RY, Quiles JM, Najor RH, Chi L, Woodall BP, Leon LJ, Duran J, Cauvi DM, De Maio A, Adler ED, Gustafsson ÃSB (2023 Feb 13). The Small GTPase Rab7 Regulates Release of Mitochondria in Extracellular Vesicles in Response to Lysosomal Dysfunction. bioRxiv : the preprint server for biology, (), . . PMID: 36824711.

16.) Sit I, Quirk E, Hettiarachchi E, Grassian VH (2022 Dec 13). Differential Surface Interactions and Surface Templating of Nucleotides (dGMP, dCMP, dAMP, and dTMP) on Oxide Particle Surfaces. Langmuir : the ACS journal of surfaces and colloids, 38(49), 15038-15049. . PMID: 36445255.

17.) Vijayakumar S, Nasr SH, Davis JE, Wang E, Zuidema JM, Lu YS, Lo YH, Sicklick JK, Sailor MJ, Ray P (2022 Dec 8). Anti-KIT DNA Aptamer-conjugated Porous Silicon Nanoparticles for the Targeted Detection of Gastrointestinal Stromal Tumors Nanoscale, 14(47), 17700-17713. . PMCID: 9744628.

18.) Sit I, Quirk E, Hettiarachchi E, Grassian VH (2022 Nov 29). Differential Surface Interactions and Surface Templating of Nucleotides (dGMP, dCMP, dAMP, and dTMP) on Oxide Particle Surfaces Langmuir, 38(49), 15038-15049. . PMCID: 9753757.

19.) Park DJ, Duggan E, Ho K, Dorschner RA, Dobke M, Nolan JP, Eliceiri BP (2022 Nov 5). Serpin-loaded extracellular vesicles promote tissue repair in a mouse model of impaired wound healing Journal of Nanobiotechnology, 20(), 474. . PMCID: 9636779.

20.) Park DJ, Duggan E, Ho K, Dorschner RA, Dobke M, Nolan JP, Eliceiri BP (2022 Nov 5). Serpin-loaded extracellular vesicles promote tissue repair in a mouse model of impaired wound healing. Journal of nanobiotechnology, 20(1), 474. . PMID: 36335351.

21.) Waggoner LE, Kang J, Zuidema JM, Vijayakumar S, Hurtado AA, Sailor MJ, Kwon EJ (2022 Sep 21). Porous Silicon Nanoparticles Targeted to the Extracellular Matrix for Therapeutic Protein Delivery in Traumatic Brain Injury. Bioconjugate chemistry, 33(9), 1685-1697. . PMID: 36017941.

22.) González-Gamboa I, Caparco AA, McCaskill JM, Steinmetz NF (2022 Sep 16). Bioconjugation Strategies for Tobacco Mild Green Mosaic Virus. Chembiochem : a European journal of chemical biology, 23(18), e202200323. . PMID: 35835718.

23.) Monroy-Borrego AG, Steinmetz NF (2022 Aug 30). Three methods for inoculation of viral vectors into plants Frontiers in Plant Science, 13(), 963756. . PMCID: 9468707.

24.) Waggoner LE, Kang J, Zuidema JM, Vijayakumar S, Hurtado AA, Sailor MJ, Kwon EJ (2022 Aug 26). Porous Silicon Nanoparticles Targeted to the Extracellular Matrix for Therapeutic Protein Delivery in Traumatic Brain Injury Bioconjugate chemistry, (), 10.1021/acs.bioconjchem.2c00305. . PMCID: 9492643.

25.) González-Gamboa I, Caparco AA, McCaskill JM, Steinmetz NF (2022 Aug 3). Bioconjugation Strategies for Tobacco Mild Green Mosaic Virus Chembiochem : a European journal of chemical biology, 23(18), e202200323. . PMCID: 9624232.

26.) Mantri Y, Sit I, Zhou J, Grassian VH, Jokerst JV (2022 May 5). Photoacoustic Enhancement of Ferricyanide-Treated Silver Chalcogenide-Coated Gold Nanorods. The journal of physical chemistry. C, Nanomaterials and interfaces, 126(17), 7605-7614. . PMID: 36249163.

27.) Mantri Y, Sit I, Zhou J, Grassian VH, Jokerst JV (2022 Apr 21). Photoacoustic Enhancement of Ferricyanide-Treated Silver Chalcogenide-Coated Gold Nanorods The journal of physical chemistry. C, Nanomaterials and interfaces, 126(17), 7605-7614. . PMCID: 9563653.

28.) Monroy-Borrego AG, Steinmetz NF (2022). Three methods for inoculation of viral vectors into plants. Frontiers in plant science, 13(), 963756. . PMID: 36110356.

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Associations

(To see more facility information, click the in the upper right)

Metadata

Links

All the links listed resolve to this core profile

https://coremarketplace.org/?FacilityID=1324
https://coremarketplace.org/RRID:SCR_022039

Institution

Institution ROR ID: https://ror.org/0168r3w48

SciCrunch Data Imports (data maintained by https://scicrunch.org)

Keywords:

USEDit, ABRF, imaging service, sample preparation service, Transmission Electron Microscopy

Resource Type:

access service resource, service resource, core facility

Citation:

University of California at San Diego Electron Microscopy Core Facility (RRID:SCR_022039)

UCSD-CMM-Electron Microscopy Core (Microscopy (Electron, Fluorescence, Optical))

Primary Contact:

Facility RRID

Additional Citation Identifiers

Facility Details

Facility Policies

(To see more facility information, click the in the upper right)

Services offered:

Facility Equipment

(To see more facility information, click the in the upper right)

Publications

(To see more facility information, click the in the upper right)

Associations

(To see more facility information, click the in the upper right)

Metadata

SciCrunch Data Imports (data maintained by https://scicrunch.org)

(To see more facility information, click the in the upper right)

Contact Guillaume Castillon

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UCSD-CMM-Electron Microscopy Core

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