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All Facilities >> University of Oklahoma Health Sciences Center >> Laboratory for Molecular Biology and Cytometry Research
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975 NE 10th Street
BRC1317
Oklahoma City, OK 73104
United Stateshttps://research.ouhsc.edu/Core-Facilities/Laboratorycite this facility
Last Updated: 05/19/2025
The OUHSC Laboratory for Molecular Biology and Cytometry Research (LMBCR) is an academic core facility offering a wide range of services involving DNA, protein, and whole cell analysis. Services include sequencing (custom PCR, plasmid and DNA, RNA, 16s, miRNA, ChIP ) and microsatellite detection via the Illumina MiSeq or SeqStudio capillary sequencer. Expression analysis can also be performed using the Nanostring nCounter SPRINT platform. Our services also include Mass Spectrometry and Proteomics using the Waters Synapt with 2D UPLC. We provide both qualitative and quantitative analysis of protein samples (cell lysate, IP, in solution) as well as simple protein identification from solution or gel slice. The Flow and Imaging division offers BSL2 cell sorting, flow cytometry, Luminex, and confocal imaging. All services are offered to OUHSC researchers, other external academic entities and industry.
Services are offerred outside of University of Oklahoma Health Sciences Center
Consulting is not offerred outside of University of Oklahoma Health Sciences Center
Computational - Bioinformatics
Sequencing - Capillary Sequencing
Sequencing - Next Generation Sequencing (NGS)
Stratedigm 96 well flow cytometers, BD FACsAria Fusion (BSL2), FACsJazz cell sorter(BSL2), Leica SP8 confocal with white light laser and live cell chamber, FACSCalibur, Nikon TE2000-E, Leica SP2_NP confocal microscope, BioPlex 200
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https://coremarketplace.org/?FacilityID=164Institution
Institution ROR ID: https://ror.org/0457zbj98Keywords:
USEDit, ABRF
Resource Type:
access service resource, service resource, core facility
Citation:
University of Oklahoma Health Sciences Center Laboratory for Molecular Biology and Cytometry Research Core Facility (RRID:SCR_021345)
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Cell Imaging
Confocal Microscope With FCS/FLIM Capabilities
Confocal Microscopy
Data Analysis
Data Analysis And Interpretation
Data Processing
Data Processing And Interpretation
Data Visualization
Deconvolution
Electron Microscopy
Image Aquisition
Image Processing And Analysis
Immunofluorescence
In-vivo Imaging
Multiphoton Microscopy
Multiphoton/ Harmonic Generation Microscope
Multiplex Fluorescence
Sample Preparation
Scanning Electron Microscopy
Tissue Embed
Microscopy (Electron, Fluorescence, Optical)
Tingting Gu
George Lynn Cross Hall 770 Van Vleet Oval University of Oklahoma
Norman, OK 73019-6131 - United States
RRID:SCR_022929
The Samuel Roberts Noble Microscopy Laboratory, the core imaging facility of the University of Oklahoma, is a central shared use facility offering access to instrumentation, training, and service using advanced light microscopy, scanning electron microscopy (SEM), and transmission electron microscopy (TEM).
Our mission is to provide effective and efficient access to core imaging and analytical characterization technologies. We welcome all OU-Norman, OUHSC, and OMRF student, faculty, and staff researchers at our centralized location the OU-Norman main campus. Clients from other universities, foundations and industry are welcome to use this equipment as well, and such work may be done on an invoice or contract basis.
In addition to instrument access, SRNML personnel offer advice, hands-on training, education, and research collaboration. The SRNML aims to promote, enable, and encourage cutting-edge education and research using the core’s instrumentation.
We have a range of sample preparation equipment available; our staff work with users and provide training. Please see our equipment and getting started pages for more information, and don’t hesitate to contact us.
This facility provides services outside its institution
This facility provides consulting outside its institution
10/27/2022
Genomics
Genotyping
Sequencing - DNA Sequencing
Sequencing - Next Generation Sequencing (NGS)
Genomics / Genome Analysis and Technologies
Graham Wiley
825 NE 13th St., MS 30
Oklahoma City, OK 73104 - United States of America
https://omrf.org/research-faculty/core-facilities/clinical-genomics-center/
RRID:SCR_025894
The Oklahoma Medical Research Foundation Clinical Genomics Center offers high-throughput sequencing and genotyping services utilizing cutting edge Illumina and Xoford Nanopore systems. Our services are available to all outside academic and corporate research entities.
This facility provides services outside its institution
This facility provides consulting outside its institution
10/14/2024
Monoclonal Antibody
Ken Smith, Ph.D.
825 NE 13th Street
Oklahoma City, OK 73104 - United States of America
http://omrf.org/research-faculty/core-facilities/human-antibody-core-facility/
RRID:SCR_017795
The mission of the Human Antibody Core Facility at OMRF is to:
•Successfully collaborate with OMRF, OUHSC and external investigators to define temporal human immune responses after vaccination and to generate human monoclonal antibodies to supplement their research.
•Develop novel methods to produce human monoclonal antibodies after acute infection and other immune events.
•Investigate new technologies for the characterization of human monoclonal antibodies produced by the core.
The Human Antibody Core Facility is one of the few laboratories in the world that produces fully-human, full-length, antigen-specific antibodies for use in studying human immune responses. The Core has achieved breakthroughs in antibody technology and has produced hundreds of high affinity protective antibodies to influenza, anthrax lethal toxin, and various S. pneumonia polysaccharides. The Core aims to support investigators by helping quantify the antibody secreting cell responses after vaccination and by generating human monoclonal antibodies to be characterized. Pathogen-specific human monoclonal antibodies are also available for licensing agreements and other forms of commercial development. The Core is expanding these services to aid additional clinical and basic science investigators inside and outside Oklahoma.
This facility provides services outside its institution
This facility does not consult outside its institution
06/27/2012
10x Genomics
Assay Development
Automated Liquid Handling
Bisulfite Conversion
Capillary Electrophoresis
CDNA Synthesis
Computational - Bioinformatics
Computational - Biostatistics
Computational - High Performance Computing
Confocal Microscopy
Genomics / Genome Analysis and Technologies
Courtney Montgomery,David Dyer
University of Oklahoma Health Sciences Center
975 NE 10th St., BRC1106
Oklahoma City, OK 73117 - United States of America
RRID:SCR_026422
Mission statement. The INBRE Data Science Core will provide state-of-the-art research data science analysis support for the Oklahoma scientific community, foster educational efforts to train Oklahoma scientists in the use of data science tools for research purposes, and promote data science education for undergraduate and high school students in the state of Oklahoma.
Summary. In pursuit of this mission, the INBRE Bioinformatics Core Facility provides support to biomedical research and educational institutions in the state of Oklahoma, other regional IDeA-participating states, and elsewhere. To date, research support has focused primarily in two areas. 1) Global analysis of gene expression data using custom spotted microarrays and commercial Affymetrix and Combimatrix arrays to examine gene expression patterns in mice, adenovirus-infected cells, and a variety of bacterial systems. Current work is transitioning to transcriptome analysis using RNA-seq methodology. 2) Genome annotation and comparative genomics analysis, including studies on several bacterial and viral pathogens important for human and agricultural disease. These studies have included informatics support for genome sequencing projects, annotation support, and post-sequence studies such as phylogenetic inference and recombination analyses. Other projects during the current funding period have focused on using bioinformatics-based strategies for developing hypotheses that are amenable to experimental testing. Bioinformatics educational support has developed a variety of resources used by INBRE network PUIs and CCs in Oklahoma, providing lecture and laboratory materials. Examples of these educational experiences include analysis of laboratory data for DNA barcoding, instructional materials for protein structure analyses and phylogenetic analyses, and microbial and viral genome sequence annotation and analysis. We have provided career counseling to undergraduate students, both individually and in large groups. We have supervised both undergraduate summer interns and high school interns to enhance interest in pursuing bioinformatics as a career path. Additionally, we have provided instructional materials for high school teachers interested in incorporating bioinformatics into their lesson plans.
This facility provides services outside its institution
This facility provides consulting outside its institution
02/12/2025
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Facility Details
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