Statistical Analysis

BioBanking+++Image Analysis (HALO/ HALO AI) Software License+++Ingenuity Pathway Analysis (IPA) Software License+++LIMS System (Freezerworks) License+++Sample Management+++Scanning 40X Brightfield+++Scanning 40X Fluorescent+++Whole Slide Scanning

CRISPR Reagent Design+++Embryo Cryopreservation & Recovery Services+++Embryo Microinjection+++Embryonic Stem (ES) Cell Injection+++Fresh/Frozen Mouse Sperm IVF+++Sperm Cryopreservation

Training And Support For The BILH I2b2 Website (https://cq2.bidmc.org)

Drug Sensitivity Testing+++Expansion And Biobanking Of Patient-derived Organoid Cultures+++Generation Of Patient-derived Organoid Cultures+++Grant Development And Grantsmanship Support+++Hands-on Training In Organoid Technology+++Protocol Development For Other Assays+++Sample Preparation For Histology

Confocal/ Super Resolution Microscope+++Dynamic Light Scattering+++Exosomes Characterisation+++FACS Cell Sorting+++Flow Cytometric Analysis+++Flow Cytometry Data Analysis+++Flow Cytometry Training +++Full Spectrum Flow Cytometry+++High Dimensional Flow Cytometry Analysis+++Imaging Flow Cytometry+++Interferometry And Immunofluorescence+++Microfluidic Pulse Sensing+++NanoFACS+++NanoFlow Cytometry Training Course+++Nanosight Nanoparticle Analysis+++Raman Spectroscopy+++RNA Flow Cytometry+++Single Particle Extracellular Vesicle Flow Cytometry+++Spectral Flow Cytometry+++UV-Vis Spectroscopy

10x Genomics Visium+++Akoya PhenoCycler Fusion+++CODEX+++Cryostat Sectioning+++Histology Stains+++Immunohistochemistry+++Multiplex Immunofluorescence+++Nanostring CosMX+++Processing & Embedding- Histology+++RNAscope+++Spatial Transcriptomics+++Tissue Clearing+++Tissue MicroArray+++Tissue Processing+++Tissue Sectioning

Biochemical Analysis+++Computational - Bioinformatics+++Data Analysis+++Gel Chromatography+++Lipidomics Profiling+++Mass Spectrometry+++Metabolomics+++Metabolomics Platform+++Protein Extraction/Purification+++Protein Post-translational Modification (PTM) Identification+++Proteomics+++Sequencing - Capillary Sequencing+++Sequencing - Protein Sequencing+++Shared Instrumentation Oversight & Maintenance+++Stable Isotope Tracing+++Western Blot

Clinical Research+++Clinical Research Coordination/Scheduling+++Clinical Trial Support+++Protocol Development/Clinical Trial Coordination

EConsent REDCap Projects+++QI/Admin REDCap Projects+++Research Electronic Data Capture (REDCap)

Biomolecular/Protein Structure Determination+++Cryo-Electron Microscopy+++Differential Scanning Fluorimetry (DSF)+++Isothermal Titration Calorimetry (ITC)+++Protein Crystallization+++Protein Design+++Protein Extraction/Purification+++Protein Interactions (IP/MS, AP/MS, Proximity Labeling, DNA-protein Interactions, Chemoproteomics)+++Protein Purification+++Recombinant Protein Production+++Thermal Protein Profiling - TPP

Clinical Registry/Repository+++Clinical Research+++Clinical Research Coordination/Scheduling+++Clinical Trial Support+++Protocol Development/Clinical Trial Coordination

Biological Photography/Photomicrography+++Confocal Microscopy+++Fluorescence TUNEL Staining-Paraffin Sections+++Fluorescence-multi-label Using Paraffin Sections+++Fluorescence-single Label Using Paraffin Sections+++Immunoperoxidase (IPOX) Using Frozen Sections+++IPOX-Paraffin Sections+++Labeling Of Frozen Sections Using A Single Fluorescence Label+++Labeling Of Frozen Sections Using Multiple Fluorescence Labels; +++Near Super-resolution Confocal Microscopy+++Pre-antibody Testing/optimization With New Antibodies.+++Pre-experiment Consultation And Consultation Prior To Antibody Purchase+++Widefield Microscopy

Contrast Staining+++Discussion Of Results (consultation) And Transfer Of Image Data Files (no Storage)+++Evaluation Of The Sample Using The JEOL 1400 Electron Microscope+++High Pressure Freezing+++Image Analysis+++Negative Staining For TEM+++Pre-experiment Consultation For Methods And For Proper Fixation Techniques+++Receipt Of Samples (sometimes Assisting With Sample Collection) Followed By Grossing And Processing Of Tissues, Suspended Cells, Bacteria, Cultured Cells, Organoids, Exosomes+++Review Of Sections For Tissue Orientation And Histopathology+++Thin Sectioning, Production And Use Of Formvar- And Carbon-coated Grids

Blank Slides Cut For Immunostaining And Passed-on (if Needed) To The Immunostaining Service +++Cassetting+++Consultation For Pre-experiment Methods, Post-processing Orientation, And/or Special Staining+++Grossing+++Labeling Of Slides+++Paraffin Or Frozen Block Sectioning+++Processing Of Tissues, Cells, Or Organoids For Frozen Sectioning+++Processing Of Tissues, Or Organoids For Paraffin Histology+++Sample Receipt+++Slides Are Boxed For Transport And Tissue Blocks Are Returned To The Investigator For Storage+++Special Processing For Specialized Project Aims Or Histology Stains Are Available +++Staining With Histology Stains Or Special Stains, Including Alcian Blue, Masson Trichrome, Oil-Red-O, PAS, Sirius Red, Toluidine Blue, And Alcian Blue/PAS

Behavioral Assessment+++Behavioral Phenotyping+++Clinical Research+++Consulting+++Data Analysis And Interpretation+++Data Visualization+++Research Design

Bioluminsecence Imaging+++Blood Cell Count+++Blood Chemistry+++Clinical Imaging - Small Animal (luminescence/fluorescence)

Consultation+++In Vivo Drug Evaluation+++In-vivo Imaging+++Xenograft / Xenotransplantation

Magnetic Resonance Imaging (MRI)

Magnetic Resonance Imaging (MRI)

Biomarker Analysis+++Digital Microscopic Assays+++Multiplexed Biomarker Assays+++Real Time Cellular Metabolism Assays+++Research Design

Computational - Bioinformatics+++Computational - Biostatistics+++Consultation+++Cytokine Assays+++Data Analysis+++Data Analysis And Interpretation+++Data Visualization+++Discovery Science+++ELISA+++Immunoassay+++Pathway Interpretation+++Proteomics+++Proteomics Analysis+++Sample Preparation+++SomaScan Proteomics

Glycolipid Analysis+++Glycomics+++Glycopeptide Mapping+++Glycoproteomics+++HPLC+++Mass Spectrometry+++Mass Spectrometry - Proteins And Peptides+++Protocol Development

Biochemical Analysis+++Consultation+++Data Processing+++Micro RNA Profiling