Provides instruments and expertise needed to visualize molecules in preparations ranging from single cells to entire animals. All facility users receive individualized instrument training as well as project specific advice for optimal data acquisition. Consultation on sample preparation, image rendering, and data analysis are also available as our knowledge base permits.

Purdue Translational Pharmacology (PTP) facility provides in vivo pharmacological evaluation using porcine models. The facility is situated in the Purdue University School of Veterinary Medicine complex, which provides constant care and monitoring of the animals. The PTP uses unique penning systems to automate blood sampling and maintain a humane and stress free environment for test subjects. The PTP synergizes with the Metabolite Profiling Facility in the Bindley Bioscience Center, which facilitates the pharmacological analysis of blood samples collected.

We provide assistance in analyzing next generation sequencing data, including RNA-Seq, ChIP-Seq, single-cell genomics, de novo assembly, gene prediction, gene annotation, mapping to reference genome, SNP/InDel analysis, smallRNA, Metagenomic and Metatranscriptomic, Phylogenomic, Proteomics and Metabolomics analyses. We also assist in integrating multi-omics data through custom workflows.

Provides LCMS/MS analysis of proteins in clinical, environmental and other biological samples. As a shared facility of the Bindley Bioscience Center (BBC) in Discovery Park of Purdue University, the facility enables both targeted and global analysis of proteins, their post-translational modifications and analysis of protein complexes and protein-protein interactions. Coupled with different chromatographic separation techniques, modern mass spectrometric instrumentation, and advanced scientific and bioinformatics expertise, the facility provides unique opportunities for researchers at Purdue and beyond to perform quantitative analysis of proteins in complex biological samples using both global, as well as, targeted proteomic approaches.

The Metabolite Profiling Facility (MPF) provides state-of-the-art technologies that enable both qualitative (defining all components of a metabolome) and quantitative (determining differential concentrations of metabolites) metabolomics in complex biological systems. This facility employs highly sensitive mass spectrometry coupled with liquid chromatography and gas chromatography for precise sample analysis. Our scientists empower researchers with new technologies, methods development, sample analysis, expert training, and consultation.

A campus-wide core facility that supports electron microscopy in the life and materials sciences. We have 14 electron microscope and expert staff scientists to help with training and project support. There are 7 scanning electron microscopes/small dual-beams and 7 transmission electron microscopes.