The Gnotobiotic Animal Core (GNAC) at the University of Washington (UW) is a core facility started in 2014 and managed by the Department of Comparative Medicine. Located in the UW Health Sciences Center, the GNAC is open to investigators with research needs to create or maintain mice free of any microorganisms (germ-free), or with a known population of microorganisms (gnotobiotic). Our facility is available to all University of Washington investigators as well as outside institutions.

The Transgenic & Genome Engineering (TGE) Core in the Department of Comparative Medicine (DCM) provides comprehensive services for generating transgenic and gene-targeted mouse models. We also offer mouse rederivation and cryopreservation to preserve and restore valuable mouse lines. All services are available to academic, industry, and nonprofit investigators.

The In Vivo Services (IVS) Core in the Department of Comparative Medicine (DCM) at the University of Washington (UW) is a core facility that provides experimental study support, rodent colony management, and technical services to those in need of in vivo support. Services are available to researchers within as well as outside the UW.

Core provides targeted and untargeted measurements of small molecule metabolites utilizing LC-MS, high-field NMR and GC-MS analytical platforms. We also perform quantitative lipidomics and oxylipns metabolic flux analysis, statistical and pathway analysis, and biological interpretation

Core has resources available at Fred Hutch and UW in collaboration with multi-disciplinary imaging research groups specializing in respective imaging technologies. Provides services including: support for animal imaging; consultation for appropriate use of imaging; training and education; help with protocol development; infrastructural support; and strategic acquisition of new imaging equipment. Provides animal imaging equipment, including MRI, PET, US and optical to support scientific projects within the UW-FH Cancer Consortium

Magnetoencephalography facility focusing on children. Equipped with MEGIN TRIUX Neo system with helium recycler, MAGSTIM EEG data acquisition system, Tucker-Davis Technologies RZ6 for stimulus generation, Epson Home Cinema 3200 for video projection, custom video recording system with 4 cameras, Eyelink eyetracker, and Polhemus 3D digitizer.

The Histology and Imaging Core (HIC) provides histology, immunohistochemistry, imaging, quantitative image analysis, and pathology consultation services. We employ extensive experience, expertise and state of the art high-throughput instrumentation across all platforms in our facility. This core is open to all investigators, including; UW and their affiliates, commercial and not-for-profit biotechnology companies, and other academic institutions. Through our partnership with the Comparative Pathology Program (CPP) we have access to experienced comparative pathologists who are available for research consultation and collaboration.